Clinical trials
Sciatica Pain clinical trials
Below are recruiting sciatica pain clinical trials, each written for real people, not researchers. We’re tracking 11 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07161323Recruiting
Trial of two exercises for leg pain from sciatica
This trial compares two simple exercises (SNAG and SNME) to see which works better for people with long-lasting sciatic leg pain. If you have had pain going down one leg for over 3 months and have not had treatment in the last month, this study may help find relief.
IstanbulAges 20–50 - NCT06696898Recruiting
Stretching with and without muscle release for sciatica
This study tests if adding myofascial release (a type of hands-on therapy for tight muscles) to a standard self-stretching program helps relieve sciatica pain and improve movement. It's for people with long-standing (chronic) one-sided sciatica.
Lahore, Punjab ProvinceAges 25–50 - NCT07632612Recruiting
Nerve-Stretching Techniques for Sciatica Pain Relief
This trial compares two hands-on physical therapy techniques—one that stretches the sciatic nerve and one that moves it gently—to see which works better for sciatica pain that has lasted several months. You'll receive one of these treatments to help reduce leg pain and improve your ability to walk and move.
Rawalpindi, Punjab ProvinceAges 20–50 - NCT07264270RecruitingPhase 1
A new injection for long-term sciatica pain
This trial tests a new medicine called C-1101, given as a shot into the spine, to see if it safely reduces pain from chronic sciatica. It is for people who have not gotten enough relief from standard treatments.
Broadmeadow, New South WalesAges 18–65 - NCT04982965RecruitingEarly Phase 1
Study brain changes behind cannabis pain relief
This early study looks at how the brain may respond to cannabis to reduce long-lasting lower back pain. You may be asked to follow strict rules about cannabis, opioids, and safety checks (including MRI) to help researchers understand the brain mechanisms.
La Jolla, CaliforniaAges 21–65 - NCT07373808Recruiting
Nerve stimulation and exercise for sciatica leg pain
This study tests whether combining a mild electrical stimulation of the sciatic nerve with specific exercises can reduce leg pain from sciatica. It is for people whose nerve-related leg pain has lasted over 6 months and is at least a 3 out of 10 in intensity.
Madrid, MadridAges 18–70 - NCT07377357Recruiting
Electrical stimulation for chronic back-related leg pain
This trial tests if a single session of electrical stimulation to the sciatic nerve can quickly reduce leg pain related to low back problems. It may help if you have had chronic sciatica (leg pain from your back) for more than 6 months and your pain has recently been interfering with daily life.
Madrid, MadridAges 18–70 - NCT07125027Recruiting
A mind-body program for leg pain from back issues
This trial tests a program called Move-MORE that combines movement and mindfulness to help people with long-lasting leg pain caused by a nerve problem in the lower back. It involves daily activities, weekly virtual group meetings, and tracking your progress with a wearable device.
Portland, OregonAges 18–66 - NCT07690449Recruiting
CT signs of nerve irritation in sciatica
This study looks at three specific signs on a CT scan that may show nerve-root irritation in people with sciatica. It only includes patients who are already scheduled for a CT-guided nerve injection to treat their pain.
Nice, Alpes MaritimesAges 18 years+ - NCT07762170RecruitingPhase 4
Steroid injections for back and pelvic pain
This study is testing how well and how safely steroid injections work for different types of back pain. If you join, you'll receive the injection as part of your care and fill out surveys about your pain and ability to do daily activities before and after.
Thornhill, OntarioAges 18 years+ - NCT07418944Recruiting
Surgery vs. non-surgery for leg pain from a slipped disc
This trial compares surgery to non-surgical treatments for people with leg pain caused by a lumbar disc herniation (slipped disc). It tests if surgery provides better relief after at least 6 weeks of symptoms.
HelsinkiAges 18–60
Hear when a new Sciatica Pain trial opens
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Common questions
- Are there clinical trials for sciatica pain?
- Yes. Clin2 currently lists 11 recruiting sciatica pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a sciatica pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a sciatica pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.