Clinical trials
Severe Acute Pancreatitis clinical trials
Below are recruiting severe acute pancreatitis clinical trials, each written for real people, not researchers. We’re tracking 36 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07308392RecruitingPhase 2
Testing HRS-7249 and SHR-1918 for severe high triglycerides at risk of pancreatitis
This trial tests two experimental drugs, HRS-7249 and SHR-1918, to lower very high triglyceride levels in people who are at high risk for pancreatitis. It aims to see if these drugs can reduce the risk of pancreatitis attacks.
Nanjing, JiangsuAges 18–80 - NCT06880770RecruitingPhase 3
Study of plozasiran for severe high triglycerides with pancreatitis
This study tests an investigational drug called plozasiran for people with severely high triglycerides that have already caused pancreatitis (inflammation of the pancreas). The goal is to see if the drug can lower triglycerides and help prevent future attacks.
Los Angeles, CaliforniaAges 18 years+ - NCT07720232RecruitingPhase 4
Probiotic plus lipid-lowering for pancreatitis from high triglycerides
This trial tests if adding a probiotic (Bacillus subtilis and Enterococcus faecium) to standard lipid-lowering therapy helps people with mild pancreatitis caused by very high triglycerides. It aims to see if the combination reduces inflammation and speeds recovery.
Xiamen, FujianAges 18–65 - NCT04647097Recruiting
Quit smoking and alcohol to prevent pancreatitis coming back
This trial is studying whether stopping alcohol and quitting smoking can help keep acute pancreatitis from returning. It’s for people whose pancreatitis happened because of alcohol, and who smoke every day.
PécsAges 18–80 - NCT04924868RecruitingPhase 3
Ursodeoxycholic acid to prevent gallstone pancreatitis returning
This trial tests whether ursodeoxycholic acid (a bile medicine) can help prevent complications from gallstone-related acute pancreatitis from coming back after you leave the hospital. It may help reduce repeat problems linked to gallstones, especially after an initial pancreatitis episode.
Santiago de Compostela, A coruñaAges 18 years+ - NCT05350371RecruitingPhase 1/Phase 2
Testing pirfenidone to treat severe acute pancreatitis
This early-stage hospital study tests whether pirfenidone is safe and tolerable for people with acute pancreatitis that may become severe. It may help by reducing the risk of complications, while researchers carefully track side effects.
Birmingham, AlabamaAges 18–85 - NCT05694988Recruiting
Filter blood to reduce inflammation in acute pancreatitis
This trial tests whether using blood “filters” plus high-volume fluid filtration can improve outcomes in adults with acute pancreatitis without infection. It aims to remove inflammatory substances from the blood early, while ensuring you’re stable enough for several hours of treatment.
MoscowAges 18–75 - NCT06080789RecruitingPhase 2
Study of a single injection of RABI-767 for severe acute pancreatitis
This trial tests a single injection of a new drug called RABI-767, given through a thin tube during an endoscopic ultrasound (EUS), to see if it can help people with severe acute pancreatitis. The drug is meant to reduce inflammation and prevent complications.
Little Rock, ArkansasAges 18–85 - NCT06113419Recruiting
Timing of gallbladder surgery after severe pancreatitis
This study looks at the best time to remove the gallbladder in people who have had a severe bout of pancreatitis caused by gallstones. It aims to see if removing the gallbladder earlier or later after recovery helps patients heal better.
Bogota, CundinamarcaAges 18 years+ - NCT06508502Recruiting
Pancreatitis Severity and Gut Bacteria Study
This study looks at how the bacteria in your gut (microbiome) might affect the severity of a first-time acute pancreatitis attack. It aims to see if certain gut bacteria can predict how serious the illness will be, which could help doctors treat patients better.
Göttingen, Lower SaxonyAges 18 years+ - NCT06835023Recruiting
Dextran and Ringer's Lactate vs. Ringer's Lactate Alone for Pancreatitis
This trial compares standard fluids (Ringer's lactate) to a combination of dextran 40 and Ringer's lactate for treating mild or moderate acute pancreatitis. It aims to see which works better for rehydration and recovery.
Satu Mare, Satu Mare CountyAges 18 years+ - NCT06867120Recruiting
Predicting pancreatitis severity with bowel sounds
This study uses a special device to listen to bowel sounds to help predict how severe acute pancreatitis will be. The goal is to find a simple, non-invasive way to guide treatment.
Beijing, Beijing MunicipalityAges 18–85 - NCT07153809Recruiting
Fecal transplant for severe acute pancreatitis recovery
This trial tests whether a fecal transplant (transferring healthy gut bacteria from a donor) can help people with severe acute pancreatitis. It is for adults who are about 2 weeks past the onset of the disease and have started to recover but still have fluid buildup in the pancreas.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT07267169Recruiting
Blood filtering for acute pancreatitis
This trial tests whether a special blood filter (Efferon LPS) can help people with moderate to severe acute pancreatitis by removing harmful substances. It is for those who have been sick for 5 days or less and have certain signs of inflammation or organ stress.
Kazan'Ages 18–75 - NCT07322978Recruiting
Blood Clots in Veins of the Gut During Pancreatitis
This study looks at how often blood clots form in veins near the gut (called splanchnic venous thrombosis) in people with acute pancreatitis. It also checks if the clots are linked to how severe the pancreatitis is. The goal is to help doctors better understand and possibly prevent these clots.
Hyderabad, TelanganaAges 18–85 - NCT07418593RecruitingPhase 4
Blood test for pancreas function in chronic pancreatitis
This trial tests a new blood test to measure how well your pancreas works. It may help people with chronic pancreatitis understand their condition and quality of life.
Baltimore, MarylandAges 18 years+ - NCT07464392Recruiting
Fecal transplant to prevent infections in severe pancreatitis
This trial tests whether a fecal microbiota transplant (FMT) can help prevent infections in people with moderately severe or severe acute pancreatitis. You may qualify if you are between 18 and 75, have had pancreatitis for 15 to 21 days, and already have a feeding tube in place.
Fuzhou, FujianAges 18–75 - NCT07583342Enrolling by invitationPhase 4
RELiZORB for feeding problems in severe pancreatitis
This study tests whether a medication called RELiZORB can help adults with moderate to severe acute pancreatitis (sudden, severe pancreas inflammation) tolerate nutrition delivered through a feeding tube. If your body is struggling to accept enough nutrition during acute pancreatitis, this trial may help you receive adequate nutrition while you recover.
Bay Shore, New YorkAges 18 years+ - NCT06976099Enrolling by invitation
Studying pancreatitis caused by high triglycerides
This study looks at people with acute pancreatitis caused by very high blood fat levels (triglycerides). It aims to collect information to better understand and treat this condition.
Beijing, Beijing MunicipalityAges 18–80 - NCT06253117RecruitingPhase 2
Testing pirfenidone to prevent repeat pancreatitis attacks
This trial tests if pirfenidone, an anti-scarring drug, can reduce the number of repeat episodes of acute pancreatitis. You may be eligible if you've had two or more pancreatitis attacks at least three months apart and are not having an active attack right now.
Birmingham, AlabamaAges 18–85 - NCT03547232RecruitingPhase 4
Indomethacin given early to treat acute pancreatitis
This trial tests whether taking indomethacin (an anti-inflammatory medicine) early can improve outcomes in people with acute pancreatitis. You might be eligible if your pancreatitis is diagnosed soon and you meet specific lab, imaging, and safety requirements.
Beijing, Beijing MunicipalityAges 18–80 - NCT04195347RecruitingPhase 1/Phase 2
CM4620 to lessen pancreatitis after asparaginase
This study tests CM4620 to reduce how severe pancreatitis becomes in children and young people with leukemia/lymphoma who develop pancreatitis after receiving a drug called asparaginase. It aims to improve outcomes by calming the inflammation of the pancreas.
Charlotte, North CarolinaAges Up to 21 years - NCT07202559Recruiting
Preventing Pancreatitis After Shock Wave Therapy for Pancreatic Stones
This study tests whether a combination of an NSAID (indomethacin) given rectally plus extra fluids through an IV can prevent pancreatitis after shock wave therapy for pancreatic stones. It may help reduce inflammation and protect your pancreas during treatment.
BaotouAges 18–85 - NCT06159244Recruiting
Gut bacteria in severe alcoholic hepatitis
This trial looks at the gut bacteria (microbiome) in people with severe alcoholic hepatitis to understand how it affects the illness. It may help doctors find better ways to treat this condition.
Amiens, PicardieAges 18–75
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Common questions
- Are there clinical trials for severe acute pancreatitis?
- Yes. Clin2 currently lists 36 recruiting severe acute pancreatitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a severe acute pancreatitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a severe acute pancreatitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.