Clinical trials
Splenectomy clinical trials
Below are recruiting splenectomy clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07205471Recruiting
Partial spleen removal via laparoscopy for cirrhosis-related hypersplenism
This study is testing a keyhole surgery to remove part of an enlarged spleen in people with cirrhosis. It aims to improve low blood counts and reduce the risk of further bleeding from stomach or esophagus veins.
Yangzhou, JiangsuAges 18 years+ - NCT03998059Recruiting
Immune testing before and after spleen removal for ITP
This study checks how your immune system is doing before and after a spleen removal surgery (splenectomy) for immune thrombocytopenia (ITP). It may help doctors better understand what changes happen in the body and how to improve care for people with ITP.
Tianjin, Tianjin MunicipalityAges 18–60 - NCT05325424Recruiting
Laparoscopic spleen surgery for people with cirrhosis
This study looks at whether removing the spleen using keyhole surgery can improve “liver reserve function” in people with cirrhosis. It may be considered for patients who have an enlarged spleen and very low platelets, but it also has several safety exclusions.
Yangzhou, JiangsuAges 18 years+ - NCT05325437Recruiting
Laparoscopic spleen surgery to protect liver function in cirrhosis
This trial looks at whether a minimally invasive spleen surgery (with a specific vein-disconnection procedure) can better protect liver function in people with cirrhosis who have had variceal bleeding. It may help reduce stress on the liver after treatment, but you must meet several safety criteria.
Yangzhou, JiangsuAges 18 years+ - NCT05338294Recruiting
Tested surgery to help immune function in cirrhosis
This study looks at whether a type of keyhole spleen surgery plus cutting a large vein can improve immune function in people with cirrhosis. It may help reduce immune problems that can happen after complications like bleeding from varices (enlarged veins in the esophagus/stomach).
Yangzhou, JiangsuAges 18 years+ - NCT06280313Recruiting
Splenectomy with targeted therapy and immunotherapy for liver cancer
This trial tests whether removing the spleen (splenectomy) can improve the effectiveness of targeted therapy and immunotherapy for people with advanced liver cancer (HCC) who also have enlarged spleens due to portal hypertension. It aims to see if this combination can help control the cancer better.
Wuhan, HubeiAges 18–75 - NCT07354893Recruiting
Teaching program after spleen removal
This study tests whether a simple teaching program helps people who had their spleen removed understand their health needs better. It may help you take better care of yourself after surgery and get the right vaccinations.
Rome, LazioAges 18 years+ - NCT07080697Recruiting
Spleen removal during pancreas surgery for severe pancreatitis
This trial tests whether removing the spleen during open surgery for infected dead pancreas tissue helps people with a specific type of high blood pressure around the spleen caused by severe pancreatitis. It may lower bleeding risk and improve recovery.
Hangzhou, ZhejiangAges 18–75 - NCT07462091Recruiting
Nerve-guided surgery for enlarged spleen and bleeding risk
This study tests a special surgery using a nerve-guided technique to remove the enlarged spleen and reduce bleeding risk in people with cirrhosis and portal hypertension. It may help if you have an enlarged spleen and have had bleeding related to liver disease.
Yangzhou, JiangsuAges 18 years+ - NCT05718726Recruiting
Study of infections after spleen removal surgery
This trial looks at what happens after surgery to remove the spleen in people who also have major cancer surgery through the belly. It may help reduce or better manage serious infections after this kind of operation.
Basingstoke, HampshireAges 18–79 - NCT07428005Recruiting
Italian questionnaire development for splenectomized patients
This study aims to create a questionnaire for patients who have had their spleen removed (splenectomy). The questionnaire will help doctors better understand and manage these patients' health needs.
Rome, LazioAges 18 years+ - NCT04166656RecruitingPhase 3
Meningococcal B vaccine testing for people without a spleen
This Phase 3 trial tests how safe and how well the immune system responds to three different meningococcal B vaccine approaches in people who do not have a spleen. It may help future adults like you choose a safer, more effective prevention strategy against meningococcal B infection.
ParisAges 18–75 - NCT06025487RecruitingPhase 2
Meningococcal B vaccine study for asplenia
This study tests a meningococcal B vaccine in adults who have had their spleen removed or have a spleen that doesn't work well (asplenia). It will compare how well the vaccine works in these patients versus healthy adults to see if it provides good protection.
Vienna, State of ViennaAges 18–60 - NCT06418256Recruiting
Study of Spleen Function Using Surgical Samples
This study collects the spleen and blood from people having surgery to remove their spleen. By studying these samples, researchers hope to learn more about how the spleen works and what happens when it doesn't function properly.
ClichyAges 18 years+ - NCT06671639Recruiting
Stanford program to speed up robotic surgery for children
This trial tests a faster, robotic-assisted surgery for children ages 6 to 21. It aims to see if completing part of the operation using a robot can be as safe and effective as traditional open surgery, possibly leading to quicker recovery and less pain.
Stanford, CaliforniaAges 6–21 - NCT07461532Recruiting
Apixaban for late portal vein clot after spleen surgery
This trial is testing whether a blood thinner called apixaban can treat a blood clot in the main vein to the liver (portal vein) that appeared more than a year after spleen surgery in people with cirrhosis. It compares apixaban to a low-dose aspirin to see if one works better with fewer side effects.
Yangzhou, JiangsuAges 18 years+ - NCT07461545Recruiting
Apixaban for late portal vein clot after spleen surgery
This trial tests if apixaban, a blood thinner, is more effective than aspirin at treating blood clots in the portal vein that form more than a year after laparoscopic spleen removal in people with cirrhosis and an enlarged spleen.
Yangzhou, JiangsuAges 18 years+
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Common questions
- Are there clinical trials for splenectomy?
- Yes. Clin2 currently lists 17 recruiting splenectomy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a splenectomy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a splenectomy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.