Clinical trials
Stimulant Use Disorder clinical trials
Below are recruiting stimulant use disorder clinical trials, each written for real people, not researchers. We’re tracking 350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06538558RecruitingPhase 1
Study of tezampanel for opioid withdrawal
This trial tests if tezampanel can help relieve withdrawal symptoms in people with opioid use disorder who are seeking treatment. Participants must already be in an outpatient addiction program.
Indianapolis, IndianaAges 18–65 - NCT06788587RecruitingPhase 2
Long-term stimulant for methamphetamine recovery
This study tests whether a high dose of a stimulant medication (lisdexamfetamine, an ADHD medicine) taken over many weeks can help people who have already completed a methamphetamine treatment program to stay off meth, reduce use, or avoid relapse.
Montreal, QuebecAges 18–55 - NCT06795581RecruitingPhase 1
Brain imaging study for alcohol use disorder
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with alcohol use disorder. The goal is to better understand how alcohol affects the brain, which may lead to new treatments.
Bethesda, MarylandAges 18–70 - NCT07056894Recruiting
Cognitive training for substance use in early psychosis
This study tests a computer-based cognitive training program to help people with early psychosis reduce their alcohol and cannabis use. The program is designed to improve thinking skills and may make it easier to cut back on substance use.
St. John's, Newfoundland and LabradorAges 16–30 - NCT05015881Enrolling by invitationPhase 2/Phase 3
Brain and heart scans in alcohol use disorder
This study uses special brain and heart scans to see how sugar (glucose) is used in people with alcohol use disorder compared with people without it. It may help researchers understand the brain–heart connection in alcohol use disorder.
Philadelphia, PennsylvaniaAges 21–65 - NCT06474026Recruiting
Focused Ultrasound for Stimulant Use Disorder
This trial tests a non-invasive brain treatment called focused ultrasound for people with stimulant use disorder (like methamphetamine or cocaine). It aims to help reduce cravings and improve recovery by gently stimulating a brain area involved in addiction.
Seoul, SeoulAges 19–60 - NCT05872750Recruiting
Brain stimulation to reduce urges in gambling disorder
This trial tests a non-invasive brain stimulation technique (theta burst stimulation) to help reduce symptoms of gambling disorder. If you meet the criteria and can safely complete the sessions, you may be able to see whether this approach lowers gambling urges or related problems.
Taipei, Taipei CITYAges 18–65 - NCT07136363Recruiting
RESTORE study: support for stimulant users leaving jail or prison
This trial tests a smartphone app (DynamiCare) to help people recovering from stimulant use (methamphetamine or cocaine) stay healthy after leaving jail or prison. It also focuses on those at risk for or living with HIV.
New Haven, ConnecticutAges 18 years+ - NCT07559500RecruitingPhase 1
Study of tirzepatide for alcohol use disorder
This trial tests if tirzepatide, a diabetes drug, affects brain chemistry linked to alcohol use. Researchers want to see if it can help people with mild-to-moderate alcohol use disorder who also have tried stimulants.
Bethesda, MarylandAges 21–65 - NCT07216872Recruiting
Deep TMS to reduce heavy drinking in alcohol use disorder
This trial tests a non-invasive brain stimulation device (Deep TMS) to help people with alcohol use disorder reduce or stop heavy drinking. It uses magnetic pulses to target brain areas linked to addiction.
Tuscaloosa, AlabamaAges 18–86 - NCT05677321Recruiting
Study how taste and smell differ in alcohol use disorder
This study compares how people with alcohol use disorder and people without it experience taste and smell. It also checks brain activity during taste/smell testing to understand individual differences that may be linked to alcohol use.
Bethesda, MarylandAges 18–65 - NCT07684976Recruiting
Safety of a helmet device using ultrasound for substance use disorder
This study tests a special helmet that uses focused ultrasound to stimulate parts of the brain involved in addiction. It aims to see if the treatment is safe and works for people with moderate to severe substance use disorder who have not gotten enough help from standard medication treatments.
Toronto, OntarioAges 18–70 - NCT06796062RecruitingPhase 2
Psilocybin for opioid use disorder
This study tests whether psilocybin can help people who want to stop using opioids and are already in treatment. Eligible participants receive a single dose of psilocybin in a supervised setting and are followed to see if it reduces opioid use.
Albuquerque, New MexicoAges 18–65 - NCT06853912RecruitingPhase 2
Psilocybin therapy for PTSD and alcohol use in veterans and first responders
This trial tests whether psilocybin, given along with psychological support, can help military veterans and first responders who have both PTSD and alcohol use disorder. If you're a veteran or first responder looking to reduce or stop drinking, you may be able to participate.
Seattle, WashingtonAges 21–65 - NCT06214065Recruiting
Brain stimulation for social thinking in autism
This trial tests whether mild brain stimulation (TMS) over the temporoparietal junction can improve a social thinking skill called 'mentalizing' in adults with autism. You would have MRI scans, cognitive tasks, and several TMS sessions.
Hartford, ConnecticutAges 18–35 - NCT05161819Recruiting
Repetitive brain magnetic treatment for somatic symptom disorder
This trial tests whether repetitive transcranial magnetic stimulation (a non-surgical treatment that uses magnets on the scalp) can help people with somatic symptom disorder. If you qualify, you would be evaluated for symptom improvement and for safety during the treatment period.
Douliu, YunlinAges 20–70 - NCT04616781RecruitingPhase 2/Phase 3
Ketone drink study for alcohol use disorder brain function
This study tests whether a ketone-based treatment (a ketone ester) can change brain activity in people with alcohol use disorder who are not currently seeking treatment. You may also have brain scans, so the study is looking for safe MRI eligibility and certain health factors.
Philadelphia, PennsylvaniaAges 21–65 - NCT06800703Recruiting
Opioid use, pain, and the brain
This study uses brain scans (MRI) to understand how pain affects people with opioid use disorder or regular opioid use, compared to healthy volunteers. It aims to find better ways to treat both pain and opioid addiction.
New Haven, ConnecticutAges 21–60 - NCT07079826Recruiting
Sparrow Link device for opioid withdrawal in hospital
This trial tests a device placed on the ear to help manage opioid withdrawal symptoms in hospitalized adults. It's for people still having withdrawal despite standard medications or those who've chosen not to take methadone or buprenorphine.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03935646RecruitingPhase 2
Test of Adderall’s short-term effects in college students with ADHD
This study measures how stimulant medication (Adderall) affects college students with ADHD in the short term. It compares people with ADHD to students without ADHD to see what changes you may notice during the study.
Laramie, WyomingAges 18–29 - NCT07469384Recruiting
Brain stimulation study for schizophrenia using tDCS
This study tests whether a mild form of brain stimulation called tDCS (transcranial direct current stimulation) can help improve symptoms of schizophrenia or schizoaffective disorder. tDCS uses small electrodes on the scalp to gently stimulate brain areas involved in vision and thinking.
Orangeburg, New YorkAges 18–55 - NCT07050862Recruiting
Personalized brain stimulation to help veterans quit smoking
This study tests a personalized brain stimulation treatment to help veterans quit smoking. It uses magnetic pulses to target brain areas involved in addiction, which may reduce cravings and make it easier to stop.
Charleston, South CarolinaAges 18–70 - NCT05702021Recruiting
Using counseling incentives to reduce stimulant use in opioid clinics
This trial tests a counseling approach called “contingency management,” which uses structured incentives to reduce stimulant use. It’s meant for people receiving treatment in specialty addiction programs and/or newly starting opioid-use medication who also use stimulants.
Chicago, IllinoisAges 18 years+ - NCT06770556Recruiting
TMS and brain scans for alcohol use disorder
This study tests whether transcranial magnetic stimulation (TMS) affects brain activity in people with and without alcohol use disorder. You'll have TMS and a brain scan (MEG) to see how your brain responds.
Winston-Salem, North CarolinaAges 21–65
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Common questions
- Are there clinical trials for stimulant use disorder?
- Yes. Clin2 currently lists 350 recruiting stimulant use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stimulant use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stimulant use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.