Clinical trials
Stimulant Use Disorder clinical trials
Below are recruiting stimulant use disorder clinical trials, each written for real people, not researchers. We’re tracking 350 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06648642Recruiting
MRI-guided brain stimulation for alcohol use disorder
This study tests whether a new type of brain stimulation, guided by MRI and a robot, can help reduce heavy drinking in people with alcohol use disorder. The treatment is non-invasive and aims to improve brain function related to cravings.
San Antonio, TexasAges 18–65 - NCT06585709Recruiting
Brain stimulation for opioid use disorder treatment
This trial tests if brain stimulation can help people starting buprenorphine for opioid use disorder. It aims to improve treatment outcomes and support recovery.
Durham, North CarolinaAges 18 years+ - NCT06578429Recruiting
Deep TMS for methamphetamine use disorder
This study uses a type of brain stimulation called deep TMS to see if it can help people with methamphetamine use disorder reduce their cravings and use. You would receive daily magnetic pulses to specific brain areas over several weeks.
Palo Alto, CaliforniaAges 25–75 - NCT06444256RecruitingPhase 2
Testing a sleep medication for people with stimulant use
This trial tests whether a medication that blocks a brain chemical involved in wakefulness can help people with stimulant use disorder sleep better. If you use cocaine or methamphetamine and have trouble sleeping, this study may be an option.
Houston, TexasAges 18–65 - NCT06513156Recruiting
Care support for hospitalized patients with drug-related infections
This study is for people who are in the hospital with a serious infection caused by injection drug use. It aims to provide better care and support while you are in the hospital and after you leave.
Washington D.C., District of ColumbiaAges 18 years+ - NCT04296604Recruiting
tDCS brain stimulation to improve thinking and mood
This study tests whether a non-surgical brain stimulation called tDCS can improve “executive function,” which means skills like planning, focus, and decision-making. It is designed for people with several mental health and substance-use conditions, and it may help you if those skills are affected by your diagnosis.
Boston, MassachusettsAges 18–65 - NCT06474026Recruiting
Focused Ultrasound for Stimulant Use Disorder
This trial tests a non-invasive brain treatment called focused ultrasound for people with stimulant use disorder (like methamphetamine or cocaine). It aims to help reduce cravings and improve recovery by gently stimulating a brain area involved in addiction.
Seoul, SeoulAges 19–60 - NCT06457230Recruiting
Brain stimulation for methamphetamine use disorder
This study tests a new type of non-invasive brain stimulation (transcranial magnetic stimulation) that targets the cerebellum and prefrontal cortex to help people with methamphetamine use disorder. It aims to see if this treatment can reduce cravings and improve outcomes.
Shanghai, Shanghai MunicipalityAges 18–60 - NCT06424184Recruiting
Fast brain stimulation for addiction and depression
This study tests a quick, non-invasive brain stimulation method (rTMS) to help people who use stimulants like cocaine or methamphetamine and also feel depressed. The goal is to see if it can reduce cravings and improve mood.
Dallas, TexasAges 18–65 - NCT06399653Recruiting
Nerve stimulation for alcohol use disorder in veterans
This study tests a non-invasive device that gently stimulates a nerve in your neck (the vagus nerve) to see if it can help reduce alcohol cravings and improve daily functioning. It is designed for veterans who struggle with heavy drinking and want to explore a new treatment option.
San Diego, CaliforniaAges 21–65 - NCT06370481Recruiting
HIV and addiction training program for Alabama clinics
This study tests a program to help people living with HIV in Alabama who also struggle with opioid or stimulant use. It takes place at your HIV clinic and checks whether a new approach to addiction care can improve your health.
Birmingham, AlabamaAges 18 years+ - NCT06323837RecruitingPhase 2
Testing mirtazapine for methamphetamine use in people on opioid treatment
This trial tests whether the antidepressant mirtazapine can help reduce methamphetamine use in people who are already receiving medication for opioid use disorder. It aims to see if adding this medication improves outcomes for those struggling with both conditions.
Spokane, WashingtonAges 18 years+ - NCT05974202Recruiting
Brain stimulation and therapy for cocaine use
This study tests a combination of brain stimulation (rTMS) and talk therapy (CBT) to help people reduce cocaine use. It's for adults who want treatment and use cocaine at least once a week.
New York, New YorkAges 22–65 - NCT05958017Recruiting
ReSET program to help stimulant use in HIV clinics
This study tests a care-support program called ReSET to improve adherence to treatment and reduce stimulant use for people living with HIV who are not currently in drug treatment. You may be offered support through HIV clinic care to help you stay on track, especially if you have access to a smartphone and stable housing.
Miami, FloridaAges 18–90 - NCT05943171Recruiting
App-based CBT for substance dependence and relationship aggression
This study tests an app-guided version of CBT (a structured talk-therapy approach) against standard CBT to help people with substance dependence and recent verbal aggression in an intimate relationship. You may be screened to see if you fit both the substance use and relationship aggression parts of the trial.
Rochester, New YorkAges 18–65 - NCT05859347Recruiting
Brain stimulation study for cannabis use disorder
This trial tests whether a treatment called repetitive transcranial magnetic stimulation (a non-surgical magnetic stimulation to the brain) can help people reduce or stop cannabis use. You may be eligible if you have cannabis use disorder and meet specific safety and symptom criteria.
Toronto, OntarioAges 18–65 - NCT05834478RecruitingPhase 3
Noninvasive vagus nerve stimulation for opioid use disorder
This trial tests whether noninvasive vagus nerve stimulation can help people with opioid use disorder during supervised withdrawal and treatment afterward. It may be considered if you can safely move to medication or behavioral care after withdrawal.
Atlanta, GeorgiaAges 18–75 - NCT05732207Recruiting
Study of brain changes in alcohol use disorder
This study looks at whether alcohol use disorder affects the cerebellum, a part of the brain involved in movement and balance. It may help researchers understand brain impacts and guide better treatments.
Baltimore, MarylandAges 25–55 - NCT04998916Recruiting
Brain stimulation to reduce heavy drinking in alcohol use disorder
This trial tests a type of noninvasive brain stimulation to see if it can reduce drinking and related “wanting” to drink. It may help people with alcohol use disorder who are currently drinking heavily.
Charleston, South CarolinaAges 21–65 - NCT04354077Recruiting
Deep brain stimulation for opioid addiction
This study tests whether deep brain stimulation (DBS), a surgical treatment that uses electrical pulses to target specific brain areas, can help reduce cravings and relapse in people with opioid use disorder who haven't found relief from other treatments.
Pittsburgh, PennsylvaniaAges 22–65 - NCT04197921Recruiting
Brain-focused ultrasound for opioid addiction-related substance use
This trial studies Exablate, a non-surgical brain treatment that aims to change activity in a specific brain area involved in cravings and substance use. It is meant for people in structured opioid or substance use treatment who are currently abstaining from opioids and other illicit drugs.
Tampa, FloridaAges 18–60 - NCT03470480Recruiting
Brain stimulation for methamphetamine cravings
This study tests whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can help reduce cravings for methamphetamine in people who have stopped using it for at least 4 weeks. If you are trying to stay off methamphetamine and struggling with cravings, this treatment might help.
Portland, OregonAges 18–65 - NCT07056894Recruiting
Cognitive training for substance use in early psychosis
This study tests a computer-based cognitive training program to help people with early psychosis reduce their alcohol and cannabis use. The program is designed to improve thinking skills and may make it easier to cut back on substance use.
St. John's, Newfoundland and LabradorAges 16–30 - NCT06795581RecruitingPhase 1
Brain imaging study for alcohol use disorder
This study uses a special brain scan (PET) to look at a protein called PDE4B in people with alcohol use disorder. The goal is to better understand how alcohol affects the brain, which may lead to new treatments.
Bethesda, MarylandAges 18–70
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Common questions
- Are there clinical trials for stimulant use disorder?
- Yes. Clin2 currently lists 350 recruiting stimulant use disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stimulant use disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stimulant use disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.