Clinical trials
Stress Disorder clinical trials
Below are recruiting stress disorder clinical trials, each written for real people, not researchers. We’re tracking 396 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05786066RecruitingPhase 2
Test whether blocking AMPA changes ketamine’s suicide relief
This study looks at whether an “AMPA receptor blocker” changes how ketamine affects suicidal thoughts in people with depression that hasn’t improved with usual treatments. If you qualify, you may receive ketamine and the study medicine, while continuing your regular mental health care.
West Haven, ConnecticutAges 21–65 - NCT06937892Recruiting
Metacognitive therapy vs. Cognitive therapy for anxiety
This study compares two different types of therapy for anxiety disorders: metacognitive therapy (which focuses on how you think about your thoughts) versus cognitive-behavioral therapy (which works on changing thoughts and behaviors). It may help you find which approach works best for you.
StockholmAges 18 years+ - NCT06746818Enrolling by invitation
Building resilience in older adults with PTSD
This trial tests if a HeartMath-based program can help older adults improve resilience, reduce posttraumatic stress, and boost spiritual and psychosocial well-being. It may be an option if you are 60 or older and have experienced trauma.
Al MansurahAges 60 years+ - NCT07118839RecruitingPhase 2/Phase 3
MDMA therapy for veterans with PTSD and alcohol use
This study tests whether MDMA-assisted therapy can help veterans who have both PTSD and alcohol use disorder. If you have tried a standard therapy before and want to reduce or stop drinking, this treatment may offer a new option.
West Haven, ConnecticutAges 18 years+ - NCT07851090Recruiting
Anger and social skills in french veterans with PTSD
This study looks at how anger and social cognition (how you read others' emotions) relate to post-traumatic stress disorder (PTSD) in former French military members. By joining, you help researchers understand these connections, which could lead to better support for veterans.
DraguignanAges 18–45 - NCT04426448Recruiting
Test a short PTSD talk therapy for people in Botswana
This study tests a brief counseling intervention for people who have PTSD symptoms. It aims to see if a short, structured approach can help reduce PTSD symptoms for adults in Botswana.
LobatseAges 18 years+ - NCT05961306Recruiting
Testing a stepped screening plan during pregnancy and after birth
This study checks how well a step-by-step screening approach and its tools work for identifying issues during pregnancy (weeks 20–24) or in early postpartum (6–10 weeks after delivery). It may help doctors use more accurate screening to decide who needs further care.
Ghent, Oost-VlaanderenAges 18 years+ - NCT02443636Recruiting
Join a depression and mental health research registry in Atlantic Canada
This trial is a “registry,” meaning you can share your health information to help researchers study depression and other mental health needs in Atlantic Canada. Being part of the registry may help researchers understand patterns and improve future support and treatments.
Halifax, Nova ScotiaAges Any age - NCT05959434RecruitingPhase 2
Therapy program to reduce drinking relapse and PTSD symptoms
This Phase 2 study tests a combined therapy approach for people who have both alcohol use disorder and post-traumatic stress disorder (PTSD). It aims to help you process stressful memories and lower the chances of relapse back to heavy drinking.
Charleston, South CarolinaAges 18 years+ - NCT02695953Enrolling by invitation
Study brain changes after trauma-focused therapy for PTSD
This study looks at how the brain works and how it changes after Cognitive Processing Therapy (CPT) for people with PTSD. You might help researchers learn why this therapy helps and who may benefit most.
Belmont, MassachusettsAges 18–55 - NCT06804525Recruiting
Adapting a mental health survey in Hong Kong
This study adapts a mental health survey for Hong Kong adults. It is open to adults aged 25 and older who live in randomly selected households and can speak Chinese or English.
Hong KongAges 25 years+ - NCT07573488Recruiting
Sleep, Stress, and Migraine: Observation and Training Study
This study explores how sleep and stress affect migraine headaches and tests whether improving sleep habits can help reduce migraines. You'll be observed and taught strategies over several months while researchers track your headaches and sleep patterns.
ZurichAges 18–65 - NCT06641115Recruiting
Integrated treatment for opioid use disorder and PTSD
This study tests a combined therapy for people with both opioid use disorder and PTSD. It aims to help you manage both conditions together, rather than treating them separately.
Charleston, South CarolinaAges 18–70 - NCT07604753Recruiting
Comparing two mental health screening questionnaires
This study compares two different questionnaires that doctors use to diagnose mental health conditions. Researchers want to check if a newer, shorter questionnaire works just as well as the longer standard one.
Hong KongAges 18 years+ - NCT07540585Recruiting
Mental health support for pregnant patients with pregnancy complications
This study tests whether providing mental health care while you're in the hospital for pregnancy-related complications can help you feel better and have better outcomes. It's designed for patients who've had difficulties with past pregnancies.
Indianapolis, IndianaAges 18–100 - NCT07473362Recruiting
Oxygen therapy in a high pressure chamber for PTSD
This trial tests whether breathing pure oxygen in a high-pressure chamber can help reduce symptoms of post-traumatic stress disorder (PTSD) in military veterans. It involves 60 daily sessions over 12 weeks, and aims to include both men and women.
Ramat Gan, Tel AvivAges 18–80 - NCT06723834Enrolling by invitation
Service Dogs and PTSD Therapy for Military Members
This study tests if pairing a psychiatric service dog with a type of talk therapy helps military-connected people with PTSD. It’s for those who have been approved to get a service dog and are not already in the same therapy.
Tucson, ArizonaAges 18 years+ - NCT07707765Recruiting
Early help after sepsis in the ICU to prevent PTSD
This study tests whether early psychological support after sepsis in the ICU can reduce the chance of developing posttraumatic stress disorder (PTSD). If you recently left the ICU after sepsis, you may be able to join.
AshkelonAges 18–120 - NCT06691347Recruiting
Trauma treatment for adults with PTSD in Norway
This study tests if a type of therapy for trauma (EMDR or trauma-focused therapy) helps people with PTSD. It is for adults in Norway who have not had these treatments before.
Drammen, AkershusAges 18 years+ - NCT06096740Recruiting
Talking therapy for PTSD and its effects on the brain
This study looks at how a specific type of talk therapy affects the way your brain processes rewards. You'd join a group that either starts therapy right away or waits a bit before starting. Your brain activity will be scanned with an MRI to see changes.
Austin, TexasAges 18–65 - NCT07015567Recruiting
Treating complex PTSD in displaced people
This study tests a psychotherapy for people with complex PTSD who are refugees or asylum seekers. It aims to help reduce trauma symptoms using culturally adapted talk therapy.
Hamburg, Free and Hanseatic City of HamburgAges 17 years+ - NCT05751473Recruiting
Reducing PTSD symptoms for first responders and frontline health workers
This study tests a way to help reduce PTSD symptoms in first responders and frontline healthcare workers. You may join a main treatment study, and some participants may also take part in follow-up questions to learn what helped.
San Diego, CaliforniaAges 18 years+ - NCT03667846RecruitingPhase 2
Biomarker-guided treatment for drinking and PTSD symptoms
This Phase 2 study tests whether blood/brain “biomarkers” can help choose a treatment plan for people who have alcohol use disorder and PTSD. The goal is to improve outcomes related to drinking and PTSD symptoms compared with a standard approach.
New York, New YorkAges 18–70 - NCT06636786RecruitingPhase 2
Medication to reduce stress symptoms after a car accident
This study tests whether a medication placed under the tongue can help prevent or reduce stress-related symptoms, like anxiety or post-traumatic stress, after a motor vehicle crash. It may help you feel better in the weeks following the accident.
Birmingham, AlabamaAges 18–55
Hear when a new Stress Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for stress disorder?
- Yes. Clin2 currently lists 396 recruiting stress disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a stress disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a stress disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.