Clinical trials
Subjective Cognitive Impairment clinical trials
Below are recruiting subjective cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 195 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06179680Recruiting
White matter changes in memory problems or Alzheimer's
This study uses brain MRI scans to look at white matter changes in people with memory problems (amnestic mild cognitive impairment) or Alzheimer's disease. It aims to understand how these changes relate to memory loss.
San Donato Milanese, MilanoAges 65 years+ - NCT07145294RecruitingPhase 1/Phase 2
Stem cell therapy to improve thinking after stroke
This trial tests whether tiny particles from stem cells can help people recover thinking and memory after a recent stroke. Doctors will check if the treatment is safe and if it boosts brain function.
ShanghaiAges 18 years+ - NCT04635657Recruiting
Testing brain function after meningioma surgery
This study measures how thinking and memory change after surgery to remove a meningioma near the front or side of the brain. It may help doctors better understand what to expect and how cognitive recovery can differ from person to person.
Columbus, OhioAges 18–89 - NCT06733714Recruiting
Brain stimulation plus memory training for older adults
This study tests whether a gentle, non-invasive electrical current applied to the scalp (tACS) combined with computer-based brain exercises can improve memory and thinking in older adults who have concerns about their cognitive health.
Rio de Janeiro, Rio de JaneiroAges 50 years+ - NCT06484244Recruiting
Walking and balance in memory loss
This study looks at how older adults with mild cognitive impairment or Alzheimer's disease adapt their walking. It aims to understand walking and balance to help people stay mobile and safe longer.
Atlanta, GeorgiaAges 50–90 - NCT02290834Recruiting
Studying brain and thinking changes after chemotherapy in older breast cancer patients
This study looks at how chemotherapy may affect memory and thinking, using thinking tests and possibly brain imaging. It compares older breast cancer patients who do and do not get chemotherapy, plus a group of healthy older adults.
Boston, MassachusettsAges 60 years+ - NCT05448768Enrolling by invitation
Testing brain stimulation in people with mild memory problems
This study tests a brain stimulation approach (TBS) to see if it can improve thinking and memory in people with mild cognitive impairment. It may also explore why it works by looking at brain-related measurements after TBS.
TaoyuanAges 50–90 - NCT06826157Enrolling by invitation
Brain Wave Patterns in Early Memory Loss and Dementia
This study uses an advanced EEG (electroencephalogram) to measure brain wave activity in people with early Alzheimer's, frontotemporal dementia, or Lewy body dementia. It aims to find patterns that could help doctors better understand the disease and predict how it might progress.
Milan, ItalyAges 50–85 - NCT03860857RecruitingPhase 3
Study biomarkers in memory aging and brain health
This Phase 3 study looks for blood/brain “biomarkers” linked to aging, memory changes, and early brain degeneration. It may help researchers better identify who is at risk and how biology relates to thinking and memory, using brain scans and thinking tests.
Irvine, CaliforniaAges 60 years+ - NCT06429215Recruiting
Virtual reality and telemedicine to lower dementia risk
This trial tests whether a program using virtual reality and telemedicine can help lower the risk of memory decline and dementia in people who feel their thinking is slipping but don't have a diagnosed memory problem.
Rome, LazioAges 55–80 - NCT07146412Recruiting
Lifestyle changes to lower dementia risk for older adults
This research study tests whether a program of healthy eating, exercise, and other lifestyle changes can lower your risk for dementia. It is designed for people aged 65–75 with a family history of dementia who want to take steps to keep their brain healthy.
Huntsville, AlabamaAges 65–75 - NCT06852209Recruiting
Brain training with neurofeedback after a stroke
This study tests a brain-training technique called neurofeedback to see if it can improve thinking skills after a stroke. If you have ongoing memory or attention problems despite recovery, this trial may help you train your brain using real-time feedback from your own brain activity.
BordeauxAges 18–75 - NCT07547319Recruiting
Accelerated rTMS to improve cognitive function
This study tests whether repeated magnetic pulses to the brain (called rTMS) can help improve thinking and memory in older adults with mild to moderate cognitive decline. The treatment is non-invasive and may help slow cognitive changes.
San Francisco, CaliforniaAges 50–90 - NCT04184375Recruiting
Memory training for older adults with bipolar disorder
This study tests whether structured memory and thinking exercises (cognitive stimulation) help older adults with bipolar disorder who have mild to moderate thinking and memory problems. You may be offered guided sessions designed to improve everyday thinking skills while checking safety and fit for the program.
La RochelleAges 65 years+ - NCT04360200Recruiting
Study of thinking changes in older adults
This trial looks at people over age 50 who have mild thinking or memory problems but do not have dementia by standard clinical criteria. It tests how these early changes are characterized and measured using exams such as blood tests and brain scans, which may help improve understanding and future care.
Guangzhou, GuangdongAges 50 years+ - NCT07027072RecruitingPhase 2
Testing KDS2010 for early Alzheimer's memory loss
This study tests a new drug called KDS2010 for people with early Alzheimer's or mild memory loss. It aims to see if the drug can slow thinking and memory decline. You will need a caregiver to help with visits and must have a special brain scan showing amyloid plaques.
Gwangju, GwangjuAges 50–85 - NCT06520878RecruitingPhase 2
Nano-PSO for memory loss in older adults
This trial tests a supplement called NANO-PSO to see if it can help thinking and memory in older adults with mild to moderate memory problems. It may be an option for people with early Alzheimer's disease.
Miguel Hidalgo, Mexico CityAges 60 years+ - NCT04123314RecruitingEarly Phase 1
Psilocybin study for depression in mild memory or early Alzheimer’s
This early-phase study tests whether psilocybin (a psychedelic substance) can help with depression in people who have mild memory problems or early Alzheimer’s. The trial also closely monitors safety, thinking changes, mood, and blood pressure before and after dosing.
Baltimore, MarylandAges 18–85 - NCT06223672Recruiting
Healthy fats for better thinking in older adults
This study tests whether healthy fats can help improve thinking and memory in people with mild memory concerns. It is for people with overweight and normal blood sugar.
Columbus, OhioAges 40–75 - NCT06809725Enrolling by invitation
Study of a headband device for cognitive health check
This study tests a new way to check cognitive (thinking and memory) health using a simple headband that measures electrical signals on your scalp. It is looking for people 65 to 90 years old, with or without memory concerns, and a family member or friend who can also take part.
Miami, FloridaAges 65–90 - NCT06640673Recruiting
Brain Wave Study for Mild Memory Problems and Parkinson's Disease
This study uses a special brain wave test (high-density EEG) to learn more about mild memory problems and how they might be linked to Parkinson's disease. If you join, you'll help researchers understand brain activity patterns that could lead to better diagnosis and care.
Lido, ItalyAges 50–90 - NCT07168824Enrolling by invitation
Can a probiotic improve memory in adults with mild cognitive decline?
This trial tests whether a daily probiotic called Lacticaseibacillus paracasei PS23 can help improve thinking and memory in adults aged 50 to 85 who feel their memory is slipping but do not have dementia or Alzheimer's disease.
TaoyuanAges 50–85 - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05791994Recruiting
Study tests visual stimulation to improve attention in mild memory issues
This study looks at whether repeated visual stimulation exercises can improve attention in people age 60+ with a specific type of mild cognitive impairment. A study team will also want you to have an informal caregiver to support participation.
AngersAges 60 years+
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Common questions
- Are there clinical trials for subjective cognitive impairment?
- Yes. Clin2 currently lists 195 recruiting subjective cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a subjective cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a subjective cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.