Clinical trials
Supplementation clinical trials
Below are recruiting supplementation clinical trials, each written for real people, not researchers. We’re tracking 675 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06507254Recruiting
Polyphenols and brain health in aging
This study tests whether eating more polyphenols (natural compounds in plants) can protect brain health in people at higher risk for Alzheimer's disease, especially if they currently eat a typical Western diet. Participants will be followed over time to see if changes in diet affect thinking and memory.
Los Angeles, CaliforniaAges 50 years+ - NCT06548048Recruiting
Dietary supplement for fat burning in overweight women
This study tests whether a dietary supplement can help your body burn fat more efficiently. It is for overweight women with regular menstrual cycles who are not using weight loss medications.
Addison, IllinoisAges 18–50 - NCT06559995RecruitingPhase 2/Phase 3
Ketone drink for alcohol withdrawal
This study tests whether a special ketone drink can ease alcohol withdrawal and help your brain heal. If you have been drinking heavily for at least 3 years and are having withdrawal symptoms now, this might be an option for you.
Philadelphia, PennsylvaniaAges 18–65 - NCT06655454RecruitingPhase 2
Numbing medicine after root canal for pain relief
This study tests whether a long-acting numbing medication (bupivacaine) given after a root canal can reduce pain better than a standard short-acting numbing medicine. It is for people who need a root canal for a tooth that is causing sharp, constant pain.
New York, New YorkAges 18 years+ - NCT06666660Recruiting
Multivitamin study for middle-aged adults
This trial tests whether taking a daily multivitamin and mineral supplement can slow or reverse biological aging in healthy middle-aged adults. It involves blood tests, wearing an OURA ring, and using a study app.
Singapore, SingaporeAges 40–60 - NCT06672952Recruiting
Citrus compound for exercise, blood flow, and stress in overweight adults
This study looks at whether a natural citrus compound called glucosyl-hesperidin (CitraPeak) can boost your exercise performance, improve blood flow, reduce stress, and sharpen thinking. Researchers want to see if it works differently for people who are moderately overweight or mildly obese.
Saint Charles, MissouriAges 18–50 - NCT06727292Recruiting
Test of a skin supplement versus placebo
This trial tests whether a food supplement can improve skin health in people with normal to dry skin. You would take the supplement or a placebo every day and have your skin checked over a few weeks.
Gdansk, GDANSKAges 45–65 - NCT06810440Recruiting
Preventing Anemia in Newly Married Women in Nepal
This study tests whether a program that combines group support and daily micronutrient supplements can help prevent anemia in newly married women in Nepal who are planning to become pregnant. It focuses on women living with their husbands and mothers-in-law.
KathmanduAges 18–25 - NCT06810466Recruiting
Dietary supplements for mild high cholesterol
This study tests two dietary supplements to see if they can improve cholesterol levels in people with mildly high cholesterol who are otherwise healthy and at low risk for heart disease.
Bologna, ItalyAges 18–69 - NCT06835816Recruiting
Amino acid supplements during dialysis
This trial tests whether adding amino acid supplements during dialysis helps people with kidney failure. It may be an option if your doctor decides you need these supplements.
StockholmAges 18 years+ - NCT06863194RecruitingPhase 1/Phase 2
Probiotics and kidney disease progression trial
This trial tests whether taking a probiotic supplement can slow down the decline of kidney function in people with moderate chronic kidney disease (CKD stages 3 and 4). If you have stable kidney disease and are not already taking probiotics, joining this study could help researchers find a new way to protect your kidneys.
Al Mansurah, DakahliyaAges 18 years+ - NCT06965426Recruiting
Eye vitamins and skin test: a crossover study
This study tests whether a supplement containing lutein, zeaxanthin, and meso-zeaxanthin can increase the amount of these nutrients in your skin. You will take the supplement and a placebo at different times to see if there is a difference.
Kansas City, MissouriAges 18 years+ - NCT06993103RecruitingPhase 4
Pasteurized donor milk for newborns of mothers with diabetes
This trial tests if giving pasteurized donor human milk to newborns of mothers with diabetes can help their health. It compares donor milk to regular baby formula as a supplement when extra feeding is needed soon after birth.
Brisbane, QueenslandAges birth–2 days - NCT07087561Recruiting
Nutrition and health education after colorectal cancer surgery
This trial tests whether a short-term nutritional supplement combined with health education can improve recovery after surgery for colorectal cancer. It is for people with stage IIa, IIb, or IIIa colon or rectal cancer who have completed surgery and are able to engage in follow-up.
Xi'an, ShaanxiAges 18 years+ - NCT07094035Recruiting
Green tea and probiotics for constipation-predominant IBS
This study tests whether a supplement containing green tea extract and probiotics can improve bowel function in people with irritable bowel syndrome (IBS) that mainly causes constipation. If you have chronic constipation and abdominal pain, this could help.
NaplesAges 18–70 - NCT07095244Recruiting
Iron supplements for kids recovering from hip surgery
This study looks at whether giving iron supplements before and after hip surgery helps children recover better. It includes children with or without neuromotor conditions.
Vancouver, British ColumbiaAges birth–18 years - NCT07120997Recruiting
Prunes to prevent bone loss during perimenopause
This study tests whether eating prunes every day can help prevent bone loss in women going through perimenopause. If you are between 44 and 55, not severely obese, and have irregular periods, you may be able to join.
University Park, PennsylvaniaAges 44–55 - NCT07135232Recruiting
Strength training and plant supplement for menopause symptoms
This 6-month study tests if strength training plus a plant-based supplement can help with perimenopause symptoms and muscle health. It's for women ages 40-55 who are not on hormone therapy and not already doing heavy resistance training.
Leeds, North HumbersideAges 40–55 - NCT07226674Recruiting
Study of gut health and plant nutrients for brain health
This trial tests whether a natural plant compound can help support memory and thinking in people at higher risk for Alzheimer's disease. You may qualify if you are over 50, overweight, eat a typical Western diet, and have a family history of Alzheimer's.
ColeraineAges 50 years+ - NCT07115563Recruiting
Amino acid supplement test for Parkinson's disease
This trial tests if taking daily amino acid supplements helps people with Parkinson's disease. You need to be on stable Parkinson's medication for at least 3 months.
Storrs, ConnecticutAges 50–80 - NCT07273630Recruiting
Protein supplement and drinking less fluid after pituitary surgery
This study tests whether a protein supplement combined with drinking less fluid can help keep sodium levels stable after pituitary surgery. It is designed for patients who are at risk of sodium imbalances after their operation.
BaselAges 18 years+ - NCT07281846Recruiting
TIPS with or without BCAA for cirrhosis and muscle wasting
This trial tests whether adding branched-chain amino acids (BCAA) to the standard TIPS procedure helps people with cirrhosis and muscle wasting. It aims to see if BCAA can improve outcomes after TIPS.
WuhanAges 18–80 - NCT07299851Recruiting
Fatty acid supplement for bone healing after a leg fracture
This trial tests whether a supplement made from cetylated fatty acids can help heal a simple leg bone fracture faster after surgery. You might be eligible if you have a specific type of leg fracture fixed with a metal rod inside the bone.
Deurne, AntwerpAges 18–85 - NCT07312409Recruiting
Taurine for long COVID vascular health
This study tests whether taking taurine supplements can improve blood vessel function and help with dizziness or fainting caused by long COVID.
Toronto, OntarioAges 18–65
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Common questions
- Are there clinical trials for supplementation?
- Yes. Clin2 currently lists 675 recruiting supplementation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a supplementation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a supplementation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.