Clinical trials
Surgical clinical trials
Below are recruiting surgical clinical trials, each written for real people, not researchers. We’re tracking 1,180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06869122Recruiting
Microwave ablation for lung cancer in surgery candidates
This trial tests a minimally invasive procedure that uses microwave energy to destroy lung tumors. It is for people who are already candidates for surgery but may want a less invasive option.
MilanAges 18 years+ - NCT06861244RecruitingPhase 2
ETMR brain tumor trial for children
This trial is for children with a rare brain tumor (ETMR) who have not had radiation. Depending on how much tumor is left after surgery and if it has spread, the study compares giving radiation early versus high-dose chemotherapy.
Birmingham, AlabamaAges Any age - NCT06868433RecruitingPhase 1
TMV vaccine alone or with pembrolizumab for advanced HNSCC
This trial tests a vaccine made from your own tumor to help your immune system fight head and neck cancer that has returned or spread. It is given alone or with an immunotherapy drug (pembrolizumab) to see if it can shrink tumors or slow progression.
Atlanta, GeorgiaAges 18 years+ - NCT06861790Recruiting
How weight loss surgery affects brain function
This study looks at how weight-loss surgery affects brain function. You will have an MRI scan and give a small blood sample before and after surgery.
Gainesville, FloridaAges 20–75 - NCT06859255Recruiting
Comparing heart valves for small aortic openings
This trial compares different types of heart valves (surgical and less-invasive) used in people with a small heart valve opening. It aims to see which valves work best, and will follow up with patients who already had the procedure.
Bari, ApuliaAges Any age - NCT06868095Enrolling by invitation
Sarcopenia’s impact on early-onset colorectal cancer
This study looks at how muscle loss (sarcopenia) affects people diagnosed with colorectal cancer before age 50. It uses CT or MRI scans taken at diagnosis to measure muscle mass and see how it relates to treatment and outcomes.
Ages 18–49 - NCT06852248Recruiting
Green dye vs. ureter stent for endometriosis surgery
This trial compares two ways of protecting the ureter during deep endometriosis surgery: placing a small tube (stent) versus using a green dye (indocyanine green) to see the ureter. The goal is to see if the dye works just as well but causes less pain and fewer side effects afterward.
Stoke-on-Trent, StaffordshireAges 18–50 - NCT06857435Recruiting
Fat graft for scar release: a new approach
This trial tests if using your own fat cells during scar surgery helps heal better. If you need surgery to release a tight scar, you may be able to receive a fat graft from your own body.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06851052Enrolling by invitation
How do DNA changes happen in health and disease?
This study is looking at DNA changes (mutations) in healthy people and in people who may have DNA damage from things like the sun, smoking, past diseases, or treatments like radiation. The goal is to better understand how these changes happen and what they mean.
CambridgeAges 18 years+ - NCT06852313Recruiting
Saving the ovaries: surgery for simple cysts in kids
This study looks at surgery to remove simple ovarian cysts in children and teens while trying to save the ovary. It aims to find the best way to treat these cysts and keep the ovary working well.
BaselAges 1–18 - NCT06857448Recruiting
Fat grafting for recent wounds and burns
This trial tests whether using your own fat cells can help heal wounds or burns that need surgery. It is for adults who have had a fasciotomy, full-thickness skin loss, or burns, and are willing to receive a fat graft.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05382962Recruiting
Using an app to help teens cope with post-surgery pain
This trial tests whether a phone app (iCanCope) can help teens better manage pain after surgery for scoliosis or certain chest conditions (pectus carinatum/excavatum). If you’re having one of these surgeries soon, the app may help with coping and day-to-day comfort after the operation.
Boston, MassachusettsAges 12–18 - NCT06843980Recruiting
Knee implant trial for inner knee pain
This trial tests a knee implant for people with pain on the inner side of the knee that gets worse with activity. It may be an option if other non-surgical treatments haven't helped.
Davis, CaliforniaAges Any age - NCT01756365Recruiting
Stem cell eye treatment from your own cornea cells
This trial tests an eye treatment made from your own cornea surface cells, grown in a lab and put back into the eye. It may help people with limbal stem cell deficiency by improving the health of the eye surface after a cell biopsy.
Toronto, OntarioAges 1 year+ - NCT06829173RecruitingEarly Phase 1
Testing a new drug with radiation for aggressive brain tumors
This trial tests a new oral drug called XRD-0394 given together with radiation therapy for people with high-grade glioma, a type of aggressive brain tumor. The goal is to see if adding this drug makes radiation more effective.
New York, New YorkAges 18 years+ - NCT06830369Recruiting
Virtual reality for comfort after major surgery in the ICU
This study tests if using virtual reality can help you feel more comfortable while recovering in the intensive care unit (ICU) after major surgery. If you are having heart or major abdominal surgery and will stay in the ICU for at least 2 days, you may be able to try a VR program to see if it eases your stay.
AmiensAges 18 years+ - NCT06824688Recruiting
Comparing robotic surgery types for rectal cancer
This trial compares two robotic surgery methods for rectal cancer: using one small incision (single-port) versus several small incisions (multi-port). The goal is to see which approach offers better outcomes while preserving the sphincter (the muscle that controls bowel movements).
ChongqingAges 18 years+ - NCT06821997RecruitingPhase 2
Chemotherapy before surgery for borderline resectable pancreatic cancer
This trial tests a combination of chemotherapy drugs (NALIRIFOX) given before surgery to shrink the tumor in people with a specific type of pancreatic cancer. The goal is to make surgery more effective and improve outcomes.
Buffalo, New YorkAges 18 years+ - NCT06823440Recruiting
Preventing nerve damage from chemo with compressive therapy
This trial tests if wearing compressive therapy (like special sleeves or stockings) during weekly paclitaxel chemotherapy can prevent nerve damage (peripheral neuropathy) in breast cancer patients. It is for people who have not yet had nerve issues or diabetes.
BrnoAges 18–70 - NCT06241170Recruiting
Surgical margin study for Crohn's disease recurrence
This trial tests a specific way of cutting the bowel during surgery for Crohn's disease to see if it lowers the chance of the disease coming back. It is for people with Crohn's in the ileocecal area who are having their first surgery to remove that section.
Guangzhou, GuangdongAges 14–65 - NCT06807437RecruitingPhase 3
Testing lanreotide before pancreas surgery to prevent leaks
This trial tests if a medicine called lanreotide, given before surgery, can prevent a common complication (pancreatic leak) after removing part of the pancreas. It is for people with pancreatic cancer or a growth that could become cancer who are scheduled for a specific type of pancreas surgery.
Birmingham, AlabamaAges 18 years+ - NCT06809582Recruiting
Body position and kidney stone removal results
This study looks at how your body’s position during surgery affects how well kidney stones are cleared. If you have stones ≤2 cm and are having a scope-based kidney stone removal, you may be able to join.
SamsunAges 18 years+ - NCT06814821Recruiting
Web-based rehabilitation after wrist surgery for osteoarthritis
This study tests a web-based rehabilitation program after certain wrist surgeries for osteoarthritis. It aims to help you recover better at home after your operation.
StockholmAges 18 years+ - NCT06800339RecruitingPhase 1
Immunotherapy and radiation before surgery for lung cancer
This trial tests combining chemotherapy, immunotherapy, and a low dose of radiation before surgery for people with non-small cell lung cancer that is borderline resectable (can potentially be removed but is close to nearby structures). It aims to see if this approach can shrink the tumor enough to allow successful surgery.
Baltimore, MarylandAges 18 years+
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Common questions
- Are there clinical trials for surgical?
- Yes. Clin2 currently lists 1,180 recruiting surgical studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.