Clinical trials
Surgical clinical trials
Below are recruiting surgical clinical trials, each written for real people, not researchers. We’re tracking 1,180 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06504381RecruitingPhase 1/Phase 2
DB107 and radiation therapy for high-grade glioma
This trial tests a new two-part treatment (DB107-RRV and DB107-FC) combined with radiation, with or without the chemotherapy drug temozolomide, for people with newly diagnosed high-grade glioma. It aims to see if this approach is safe and effective.
Los Angeles, CaliforniaAges 18 years+ - NCT06503406Recruiting
Testing a new dressing for deep wounds to speed healing
This trial tests a special wound dressing (SupraSDRM®) to help deep, full-thickness wounds heal faster and reduce the time needed before a skin graft can be placed. It may be an option for people with a large, deep wound from an injury, surgery, or burn that isn't ready for a graft yet.
Fort Sam Houston, TexasAges 18–85 - NCT06487507Recruiting
Mediterranean diets for men before prostate surgery
This study tests whether a medically designed Mediterranean diet can help men before prostate cancer surgery. You would eat special foods and be monitored closely to see how the diet affects your health and recovery.
Miami, FloridaAges 18–80 - NCT06492954RecruitingPhase 1
Testing atezolizumab with radiation and surgery for lung-only osteosarcoma
This trial tests whether combining an immunotherapy drug (atezolizumab) with focused radiation and surgery can help people whose osteosarcoma has come back only in the lungs. It aims to see if this approach is safe and may improve outcomes.
Atlanta, GeorgiaAges Up to 50 years - NCT06484374Recruiting
AI-robot guided surgery for large basal ganglia bleeding
This trial tests a new, less invasive brain surgery using a robotic arm guided by artificial intelligence (AI) to remove a large blood clot caused by a hemorrhagic stroke in the basal ganglia. It may be an option for people who can have surgery soon after the stroke and were previously independent.
NanjingAges 18 years+ - NCT06483256Recruiting
Outcomes after surgery for biceps tendon injury
This study looks at how well patients do after surgery for a biceps tendon injury, using a specific surgical technique. It may help you understand what results to expect if you have had this type of surgery.
BolognaAges 18 years+ - NCT06484660Recruiting
Less invasive surgery for complex anal fistula
This study tests a less invasive surgical method (a mucosal advancement flap) for treating complex anal fistulas. It aims to see if this approach works well for people who have a single fistula tunnel and haven't had this type of operation before.
Palma de Mallorca, Balearic IslandsAges 18 years+ - NCT06460922Recruiting
3D printed wrist models to plan Kienböck's surgery
This study uses 3D printed models of your wrist to help doctors plan surgery for Kienböck's disease (a condition where a wrist bone loses blood supply and breaks down). The goal is to see if these models improve surgical results.
Barcelona, BarcelonaAges 18–85 - NCT06456554Recruiting
Dermal matrix study in breast reconstruction
This trial tests a special supportive material called acellular dermal matrix in women having two-stage breast reconstruction after mastectomy. The goal is to learn how well it works when the implant is placed directly under the skin, over the chest muscle.
Little Rock, ArkansasAges 22 years+ - NCT04319848RecruitingPhase 1
Tissue-engineered cornea transplant for specific eye swelling conditions
This Phase 1 trial tests a new, lab-made tissue transplant to improve corneal clarity in people with certain types of corneal endothelium failure (eye swelling) caused by specific conditions. The main goal is to check safety and see if vision and corneal health improve.
SingaporeAges 21–80 - NCT05114876Recruiting
Tested a new plan to support older adults after surgery
This study looks at a redesigned surgical care plan to better support older adults who may have memory or thinking changes after major planned surgery. If you qualify, you would be assessed before surgery and followed after to see whether this approach helps.
Toronto, OntarioAges 60 years+ - NCT06443138Recruiting
Preparing older cancer patients for procedures
This trial is for people aged 70 or older who have cancer and are scheduled for surgery. It tests a program to help you prepare for surgery or other medical procedures, like special exercises or support, to make recovery easier.
NiceAges 70 years+ - NCT06449313RecruitingPhase 2
Immunotherapy before lung cancer surgery for stage 3 disease
This trial tests whether giving chemotherapy plus immunotherapy before surgery can help shrink stage 3 lung cancer and improve outcomes. The goal is to make the tumor easier to remove and possibly lower the chance of it coming back.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06459427Recruiting
Robot-assisted surgery for brainstem hemorrhage
This trial tests a new, less invasive surgery using a robot to help guide the doctor to drain blood from a brainstem bleed. It may be an option for people who can have surgery soon after the bleed and who have a certain level of consciousness.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05757817Recruiting
New flap surgery for mouth or throat cancer reconstruction
This trial studies whether a new surgical reconstruction method can improve outcomes for people with oral cavity or oropharyngeal squamous cell carcinoma (a type of head and neck cancer). The goal is to rebuild the area using a tissue flap while reducing problems where the tissue is taken from.
MontpellierAges 18 years+ - NCT04029363Recruiting
Transcatheter mitral valve procedure for high-surgery-risk patients
This trial studies a newer, catheter-based mitral valve treatment in people with moderate-severe to severe mitral valve leaking who are at high risk for open-heart surgery. It may help improve symptoms and heart function without traditional surgery, but you must meet key heart, anatomy, and safety requirements.
Darlinghurst, New South WalesAges 18 years+ - NCT04515459RecruitingPhase 2
Pre-surgery exercise and care program for limb sarcoma
This Phase 2 trial tests a “prehabilitation” program done before surgery to help people with arm or leg (limb) sarcoma be better prepared for their operation. It may help improve how well patients tolerate treatment and recover by planning supportive care around the weeks before surgery.
ToulouseAges 16 years+ - NCT06439953Recruiting
Irrigation solution for spinal surgery instrumentation
This trial tests a solution used to clean the surgical site during spine surgeries to see if it helps prevent infections. It is for patients having certain types of spine surgery for conditions like deformity, cancer, or trauma.
Providence, Rhode IslandAges 18 years+ - NCT06422273Enrolling by invitationPhase 3
TXA vs Saline to Prevent Bleeding After Lung Transplant Biopsy
This trial tests whether a medication called tranexamic acid (TXA) can help prevent bleeding after a lung transplant biopsy. It compares TXA to a saltwater solution (saline) to see if it reduces the need for procedures to stop bleeding.
Grand Rapids, MichiganAges 18 years+ - NCT06423326RecruitingPhase 2
Chemotherapy before surgery for pancreatic cancer
This trial tests a combination of three chemotherapy drugs given before surgery for pancreatic cancer that is removable or borderline removable. The goal is to shrink the tumor to make surgery more successful.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06408116RecruitingPhase 2
FAPI-PET Scan for Esophageal Cancer Surgery Planning
This trial tests whether a special PET scan called FAPI-PET can better show the edges of esophageal tumors before surgery. It may help doctors plan more precise surgery.
HeidelbergAges 18 years+ - NCT06418243Recruiting
3D modeling for surgery on children's pelvic and retroperitoneal tumors
This trial uses 3D computer models of children's tumors to help surgeons plan and perform safer operations. It is for children with tumors in the pelvic area (lower belly) or retroperitoneal area (deep in the back of the belly) who need an MRI or CT scan before surgery.
Paris, Île-de-France RegionAges 3 months–17 years - NCT06384183Enrolling by invitation
Real-world fish skin graft registry study
This study tracks how well a fish skin graft (Kerecis) heals wounds in real patients. It helps doctors learn more about who benefits most from this treatment.
Sarasota, FloridaAges Any age - NCT06394908Enrolling by invitation
Registry of Mini-Invasive Stone Surgery (MIUS)
This registry collects information on people being treated for kidney stones (urolithiasis) to help doctors learn which treatments work best. It includes patients of any age who have a medical reason for treatment and who allow their records to be used.
IstanbulAges Any age
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Common questions
- Are there clinical trials for surgical?
- Yes. Clin2 currently lists 1,180 recruiting surgical studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a surgical trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a surgical trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.