Clinical trials
Symptom clinical trials
Below are recruiting symptom clinical trials, each written for real people, not researchers. We’re tracking 929 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05641116Recruiting
Exercise plus education program for long-lasting Lyme-related symptoms
This trial tests whether a combined program of adapted exercise and therapeutic education can improve long-lasting symptoms that are thought to be related to Lyme disease. It may help people who have symptoms for over 6 months and are not very active currently.
Clermont-FerrandAges 18 years+ - NCT05658796Recruiting
Program to reduce opioid use after hip or knee replacement
This trial tests a support program called RXWell to help people use less opioid pain medicine after elective hip or knee replacement surgery. It may help by addressing anxiety and depression symptoms that can affect pain and recovery.
Monroeville, PennsylvaniaAges 18–100 - NCT05671185Recruiting
Brain stimulation for schizophrenia symptoms and depression
This study tests repeated brain stimulation (rTMS) to see if it can improve symptoms of schizophrenia and related depression, and measure body/brain changes. You may be considered if you have schizophrenia or schizoaffective disorder with enough depressive symptoms, and if recent treatments and medical safety factors fit the rules.
Douliu, YunlinAges 20 years+ - NCT05686525Recruiting
TUMT vs PAE to ease severe urinary symptoms from an enlarged prostate
This trial compares two catheter-based treatments—TUMT and PAE—to see which better reduces severe urinary symptoms caused by an enlarged prostate (BPH). It may help you choose a treatment option if medicines are not suitable or you still have significant symptoms.
Copenhagen, Copenhagen NAges 40 years+ - NCT05714917Recruiting
Studying recovery after nerve damage from NOS use
This study looks at how neurological symptoms (like numbness, weakness, unsteadiness, or walking problems) recover after damage caused by NOS use. It may help researchers understand what recovery looks like and what support or treatments could work best.
BirminghamAges 16–40 - NCT05726721Recruiting
Study of treatment targets for binge eating disorder
This trial studies how binge eating disorder behaves during treatment and compares patterns over time. It may help by improving future treatment approaches for people with binge eating disorder.
Aarhus, Central JutlandAges 18 years+ - NCT05733091Recruiting
Study of symptoms and function after certain head and neck cancers
This study looks at how symptoms and everyday functioning change for people with cancers of the nose/sinuses, the throat behind the nose (nasopharynx), or nearby skull-base areas. It may help doctors understand what survivors experience and improve long-term care.
Houston, TexasAges 18 years+ - NCT05733520Recruiting
Telehealth coaching for Alzheimer’s caregivers using a phone
This trial tests a mobile telehealth program designed to help unpaid caregivers reduce Alzheimer’s-related symptoms in the people they care for. If you’re a primary caregiver, you may get study sessions using a smartphone or similar device.
Indianapolis, IndianaAges 18 years+ - NCT05734547Recruiting
Support for children after trauma through parent-and-child sessions
This trial offers a structured program for children who have ongoing trauma symptoms after a scary or harmful event, with work involving both the child and a parent/caregiver. It aims to reduce post-trauma stress symptoms and help the child feel safe again.
AskerAges 7–12 - NCT05741775RecruitingPhase 3
Physiotherapy program for migraine symptoms
This trial tests whether a physiotherapy treatment can reduce migraine symptoms. You may be eligible if you have likely migraine headaches and meet the trial’s symptom screening rules.
Kajang, SelangorAges 18–40 - NCT05748028Recruiting
Testing treatment for pain and nerve symptoms in Parkinson’s
This study looks at pain and “autonomic” (automatic body) symptoms in people with Parkinson’s disease or a related condition called multiple system atrophy. It aims to understand what helps and to learn more about these symptoms in different types of Parkinson-like illnesses.
Telese Terme, BeneventoAges 18 years+ - NCT05752448Recruiting
Care plan support for women after ovarian cancer treatment
This trial looks at survivorship care—how to help women after ovarian cancer treatment. It may improve follow-up planning and support during the first months after treatment ends.
Dallas, TexasAges 18 years+ - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT05757687Recruiting
Omega System for urinary symptoms from enlarged prostate
This trial studies a device called the Omega System to see if it is safe and effective for urinary problems caused by an enlarged prostate (BPH). You may be a better fit if you have moderate-to-severe symptoms and prostate measurements that match the study plan, and if you are scheduled for prostate surgery or need evaluation for BPH.
TbilisiAges 50 years+ - NCT05762952RecruitingPhase 1
Dapagliflozin study for heart micro-blood-flow symptoms in women
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
Charlottesville, VirginiaAges 18–99 - NCT05765864Recruiting
Study of self-harm in at-risk teens
This study looks at self-harm and thoughts/behaviors related to safety in teenagers who are considered at higher risk. It may help researchers better understand what supports are needed for teens who self-harm without wanting to die.
LjubljanaAges 13–18 - NCT05776251Recruiting
Noninvasive nerve stimulation for ongoing Lyme symptoms
This trial tests whether taVNS (a noninvasive nerve stimulation done through the skin near the ear) can reduce long-lasting symptoms after Lyme disease. It targets people whose symptoms have stayed for months after standard antibiotic treatment.
New York, New YorkAges 18–65 - NCT05799001Recruiting
Dance workshops for seniors with dementia behavior changes
This trial tests whether structured dance sessions can help improve behavioral and emotional symptoms in people with dementia living in care facilities. It may help by offering a gentle, guided activity while keeping medications stable.
Craponne-sur-ArzonAges 65 years+ - NCT05802004Recruiting
Sound stimulation to improve sleep and emotions in young adults
This study tests whether gentle sound stimulation during sleep can improve sleep and how you think and feel in daily life when you have anxiety or depression symptoms. You’ll also do sleep testing in a lab and complete questionnaires to measure changes.
Pittsburgh, PennsylvaniaAges 18–25 - NCT05803993Recruiting
Fecal transplant to ease constipation in irritable bowel syndrome
This trial tests whether transferring stool bacteria to the gut (fecal microbiota transplantation) can reduce symptoms of irritable bowel syndrome with constipation. It may help by changing the gut microbiome, but you must meet safety and health requirements.
RomaAges 18 years+ - NCT05803980Recruiting
Fecal transplant to ease IBS diarrhea symptoms
This study tests whether fecal microbiota transplantation (a stool-based treatment to change gut bacteria) can reduce symptoms of irritable bowel syndrome (IBS) that comes with diarrhea. You may be eligible if you’re an adult with diarrhea-predominant IBS and recent colonoscopy results that rule out other intestinal diseases.
RomaAges 18 years+ - NCT05827406Recruiting
Support system for psychiatric checkups in adults
This study looks at a helpful support system to improve how psychiatric symptoms are diagnosed and followed over time. It may help patients and clinicians by making checkups and next steps more organized.
StockholmAges 18 years+ - NCT05832489RecruitingPhase 3
EEG-MRI test of methylphenidate in adult attention symptoms
This Phase 3 study tests how methylphenidate affects brain signals and attention in adults with ADHD, and in adults with mood-related attention problems. It also includes healthy volunteers to compare brain responses during brain scanning.
StrasbourgAges 18–60 - NCT05834478RecruitingPhase 3
Noninvasive vagus nerve stimulation for opioid use disorder
This trial tests whether noninvasive vagus nerve stimulation can help people with opioid use disorder during supervised withdrawal and treatment afterward. It may be considered if you can safely move to medication or behavioral care after withdrawal.
Atlanta, GeorgiaAges 18–75
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Common questions
- Are there clinical trials for symptom?
- Yes. Clin2 currently lists 929 recruiting symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.