Clinical trials
Symptom clinical trials
Below are recruiting symptom clinical trials, each written for real people, not researchers. We’re tracking 940 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06493825Recruiting
Mindfulness app for kids with severe tinnitus or misophonia
This trial tests whether a virtual reality mindfulness app can help children aged 10–18 with severe tinnitus or misophonia feel better mentally. It compares the mindfulness app to a placebo (sham) version.
Aurora, ColoradoAges 10–18 - NCT06494735Recruiting
French self-help book program for OCD symptoms
This study tests a French self-help book program designed to help people with OCD change how they think about their obsessions. If you have OCD and your medication has been stable for 3 months, you may be able to join.
NiceAges 18 years+ - NCT06511908RecruitingPhase 2
Testing a new ketamine-like drug for hard-to-treat depression
This study tests a new experimental drug (2R,6R)-HNK, a chemical related to ketamine, given by IV infusion to see if it can help people with depression that hasn't improved with other treatments. The goal is to find a new option for people who have not found relief from standard antidepressants.
Bethesda, MarylandAges 18–70 - NCT06515106Recruiting
Living with LGI1 encephalitis: a study on long-term symptoms
This study looks at symptoms, biomarkers, and mechanisms of the chronic phase of LGI1 antibody-mediated encephalitis. It aims to understand what happens after the acute stage and how to better manage long-term effects.
Barcelona, CataloniaAges Any age - NCT06532773RecruitingDurham, North CarolinaAges 18 years+
- NCT06537752Recruiting
Study on symptoms of ethanol in breast cancer patients
This trial checks how breast cancer patients react to ethanol (alcohol) during chemotherapy with docetaxel. It aims to understand side effects and safety for people getting this treatment.
SeoulAges 19 years+ - NCT06538311RecruitingEarly Phase 1
TMS treatment for early Alzheimer's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help people with early Alzheimer's disease or related memory problems. It's a safe, gentle way to stimulate brain cells using magnetic pulses.
Boston, MassachusettsAges 40–99 - NCT06547489RecruitingPhase 2
Testing zelquistinel for major depression
This study tests whether zelquistinel, an investigational drug, can reduce symptoms of major depressive disorder (a type of clinical depression). It is for people who are currently experiencing a moderate to severe depressive episode and are not taking other antidepressants.
Birmingham, AlabamaAges 18–64 - NCT06548256Recruiting
Probiotic for Parkinson's Symptoms
This trial tests whether a probiotic called Clostridium butyricum can help with both movement and non-movement symptoms of Parkinson's disease. It aims to see if improving gut health can ease symptoms.
Kaohsiung CityAges 20–90 - NCT06549777Recruiting
Body-focused therapy for childhood trauma survivors
This trial tests a therapy that uses body awareness and movement to help adults who experienced child maltreatment and have trauma-related symptoms. It may help you feel safer and more connected.
Stockholm, Stockholm CountyAges 18–100 - NCT06551974Recruiting
A mobile app to help with eating disorders
This study tests a mobile app that provides guided self-help for people with eating disorders. If you are an Italian-speaking adult with eating concerns—either recently in treatment or monitored by your doctor—this app might help you improve your recovery.
CatanzaroAges 18 years+ - NCT06553430Recruiting
Aerobic exercise for children with ADHD
This study tests whether regular aerobic exercise can improve ADHD symptoms, thinking skills, and quality of life in children. It offers a structured exercise program as an add-on to any current medication.
Guangzhou, ShenzhenAges 7–14 - NCT06555588Recruiting
Supportive talk therapy for advanced cancer symptoms
This study tests a supportive talk therapy program (called Engage) delivered via video calls. It aims to help people with advanced cancer manage tough symptoms like pain, fatigue, and distress and improve daily functioning.
Durham, North CarolinaAges 18 years+ - NCT06559306RecruitingPhase 3
Seltorexant for depression with insomnia symptoms
This trial tests if adding seltorexant to your current antidepressant can improve depression and sleep problems. It is for people with major depressive disorder who still have symptoms, especially insomnia, despite trying at least one antidepressant.
Birmingham, AlabamaAges 18–74 - NCT06562231Recruiting
Isthmocele symptom and quality of life scale
This study is developing a questionnaire to measure how much a isthmocele (a pocket or weakness in the scar from a C-section) affects your quality of life. If you have symptoms like pain or bleeding after your cesarean, your answers will help create a better way to understand and treat this condition.
SakaryaAges 18–45 - NCT06564415Recruiting
Laser treatment registry for enlarged prostate symptoms
This study is a European registry tracking how a laser treatment (TPLA) helps men with an enlarged prostate and bothersome urinary symptoms. It aims to see how safe and effective this new procedure is for daily life.
FlorenceAges 18 years+ - NCT06569173Recruiting
Comparing two types of ureteral stents for children with kidney stones
This study compares whether a special anti-reflux stent causes fewer symptoms than a standard DJ stent in children treated for kidney stones. The goal is to find which stent is more comfortable and has fewer side effects.
Hangzhou, ZhejiangAges birth–18 years - NCT06573320Recruiting
Exercise for schizophrenia patients on clozapine
This trial tests whether a regular exercise program can help improve symptoms, thinking, and quality of life for people with schizophrenia who take a specific medication called clozapine.
IstanbulAges 18–65 - NCT06574035Recruiting
Exercise and counseling for Black men with diabetes
This study tests whether a program combining physical activity with cognitive behavioral therapy (a type of talk therapy) helps African American men manage type 2 diabetes better. You would attend weekly exercise and counseling sessions for several months.
Ann Arbor, MichiganAges 18 years+ - NCT06577779RecruitingPhase 4
Testing Jornay PM for adult ADHD symptoms into the evening
This study tests if Jornay PM, a long-acting ADHD medication, helps control symptoms, focus, and emotions throughout the day and into the early evening in adults with ADHD. It is an open-label study, meaning everyone knows they are getting the medication, and then they are randomly assigned to different observation groups.
New York, New YorkAges 18–60 - NCT06579950Recruiting
Cool roofs and health study
This study tests whether a special cool roof coating can lower indoor temperatures and improve health. You may be eligible if you live in a home with a stable, safe roof.
OuagadougouAges 18 years+ - NCT06582212Recruiting
Managing Hormonal Triggers in Women with Parkinson's
This study helps women with Parkinson's disease who are still having periods learn how hormonal changes may affect their symptoms. You will be guided to identify and manage these triggers better.
Grenoble, GrenobleAges 18–56 - NCT06582784Recruiting
Using a phone app to help cancer survivors with depression
This study tests a mobile app to help cancer survivors who are feeling depressed. If you have a smartphone and are willing to use an app for mood support, you may be able to join.
Charleston, South CarolinaAges 18 years+ - NCT06586619Recruiting
Tai chi and qigong for older adults with HIV
This study tests whether a remotely taught tai chi and qigong program can improve mood and well-being in people aged 50–75 who are living with HIV. You can join from home using a smartphone.
Miami, FloridaAges 50–75
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Common questions
- Are there clinical trials for symptom?
- Yes. Clin2 currently lists 940 recruiting symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.