Clinical trials
Symptom clinical trials
Below are recruiting symptom clinical trials, each written for real people, not researchers. We’re tracking 909 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06575712Recruiting
Coping skills training to manage symptoms and daily steps
This study tests a coping skills training program to help people who have had a stem cell transplant or CAR-T cell therapy for blood cancer manage fatigue, pain, and stress. It may help you feel better and be more active in daily life.
Durham, North CarolinaAges 18–99 - NCT06582212Recruiting
Managing Hormonal Triggers in Women with Parkinson's
This study helps women with Parkinson's disease who are still having periods learn how hormonal changes may affect their symptoms. You will be guided to identify and manage these triggers better.
GrenobleAges 18–56 - NCT06577779RecruitingPhase 4
Testing Jornay PM for adult ADHD symptoms into the evening
This study tests if Jornay PM, a long-acting ADHD medication, helps control symptoms, focus, and emotions throughout the day and into the early evening in adults with ADHD. It is an open-label study, meaning everyone knows they are getting the medication, and then they are randomly assigned to different observation groups.
New York, New YorkAges 18–60 - NCT06582784Recruiting
Using a phone app to help cancer survivors with depression
This study tests a mobile app to help cancer survivors who are feeling depressed. If you have a smartphone and are willing to use an app for mood support, you may be able to join.
Charleston, South CarolinaAges 18 years+ - NCT06579950Recruiting
Cool roofs and health study
This study tests whether a special cool roof coating can lower indoor temperatures and improve health. You may be eligible if you live in a home with a stable, safe roof.
OuagadougouAges 18 years+ - NCT06559306RecruitingPhase 3
Seltorexant for depression with insomnia symptoms
This trial tests if adding seltorexant to your current antidepressant can improve depression and sleep problems. It is for people with major depressive disorder who still have symptoms, especially insomnia, despite trying at least one antidepressant.
Birmingham, AlabamaAges 18–74 - NCT06562777Recruiting
How symptoms differ between men and women during immunotherapy
This study looks at how symptoms during immunotherapy (a cancer treatment that boosts your immune system) may differ between men and women. Researchers will follow people with cancer who are starting immunotherapy to see if men and women report different side effects.
Portland, OregonAges 18 years+ - NCT06555588Recruiting
Supportive talk therapy for advanced cancer symptoms
This study tests a supportive talk therapy program (called Engage) delivered via video calls. It aims to help people with advanced cancer manage tough symptoms like pain, fatigue, and distress and improve daily functioning.
Durham, North CarolinaAges 18 years+ - NCT06547489RecruitingPhase 2
Testing zelquistinel for major depression
This study tests whether zelquistinel, an investigational drug, can reduce symptoms of major depressive disorder (a type of clinical depression). It is for people who are currently experiencing a moderate to severe depressive episode and are not taking other antidepressants.
Birmingham, AlabamaAges 18–64 - NCT06537752Recruiting
Study on symptoms of ethanol in breast cancer patients
This trial checks how breast cancer patients react to ethanol (alcohol) during chemotherapy with docetaxel. It aims to understand side effects and safety for people getting this treatment.
SeoulAges 19 years+ - NCT06538311RecruitingEarly Phase 1
TMS treatment for early Alzheimer's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help people with early Alzheimer's disease or related memory problems. It's a safe, gentle way to stimulate brain cells using magnetic pulses.
Boston, MassachusettsAges 40–99 - NCT06532773Recruiting
Mindfulness for better sleep during blood cancer treatment
This study tests whether learning mindfulness (a way of focusing attention and calming the mind) can help improve sleep and manage symptoms for people with blood cancers who are in the hospital. It may give you coping skills to feel better during and after your treatment.
Durham, North CarolinaAges 18 years+ - NCT06511908RecruitingPhase 2
Testing a new ketamine-like drug for hard-to-treat depression
This study tests a new experimental drug (2R,6R)-HNK, a chemical related to ketamine, given by IV infusion to see if it can help people with depression that hasn't improved with other treatments. The goal is to find a new option for people who have not found relief from standard antidepressants.
Bethesda, MarylandAges 18–70 - NCT06487533Recruiting
Sensing opioid withdrawal and cravings with wearable sensors
This study uses wearable sensors to track physical signs of opioid withdrawal and cravings over 14 days. It aims to better understand these symptoms in people currently taking or planning to start medication for opioid use disorder.
Center City, MinnesotaAges 18–50 - NCT06480019Recruiting
Group talk therapy for depression in young adults
This study tests if a group therapy program led by non-professionals can help reduce depressive symptoms in young adults aged 18-24 who live, work, or study in Porto Alegre, Brazil. You may benefit if you have mild to moderate depression but no risk of suicide.
Porto Alegre, Rio Grande do SulAges 18–24 - NCT06460116Recruiting
Helping Teens in Southeast Kansas Attend School More
This study tests a program that uses community health workers to help teens in Southeast Kansas who have missed a lot of school. The goal is to improve attendance and health.
Kansas City, KansasAges 12 years+ - NCT06467695Recruiting
Low voltage brain stimulation for depression in Parkinson's
This study tests whether a gentle, low-voltage electrical stimulation (tDCS) can help improve depression in people with Parkinson's disease. It involves coming to the lab for sessions where a small device sends a mild current to your brain, and you'll also have an EEG (a non-invasive brain wave recording).
Mobile, AlabamaAges 19–65 - NCT06465511Recruiting
Supportive clinic for advanced or metastatic cancer
This study offers a supportive care clinic for people with advanced or metastatic cancer. The goal is to help manage symptoms and improve quality of life during treatment.
Hong KongAges 18 years+ - NCT06454903Recruiting
Smartphone app support for veterans treating opioid use disorder
This study tests a smartphone app to support Veterans in their recovery from opioid use disorder. The app aims to improve daily functioning alongside medication treatment.
West Haven, ConnecticutAges 18 years+ - NCT06449326Recruiting
Brain imaging and stimulation study for PTSD in veterans
This study uses brain scans and a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to help reduce PTSD symptoms in veterans. You may be eligible if you have ongoing PTSD symptoms and are on stable medication.
Albuquerque, New MexicoAges 18–80 - NCT06442423RecruitingPhase 1
Psilocybin study for people with psychiatric symptoms
This trial tests if psilocybin, a substance found in certain mushrooms, can help people with various mental health symptoms that affect daily life. You would take a single dose in a supervised setting and be monitored for changes in your mood and well-being.
New Haven, ConnecticutAges 18 years+ - NCT06450431Recruiting
Parathyroid symptom assessment study
This study looks at how your parathyroid condition affects your symptoms and quality of life. You will fill out a simple questionnaire about your health.
Nantes, Loire-AtlantiqueAges 18 years+ - NCT06446869Recruiting
Probiotic for menopause symptoms
This study tests whether a probiotic supplement can help reduce hot flashes and other menopause symptoms. It is for women who are in early menopause and have frequent hot flashes.
Glasgow, GlasgowAges 42–60 - NCT06452095Recruiting
Hyperbaric oxygen therapy for long COVID brain fog
This trial tests if hyperbaric oxygen therapy (breathing pure oxygen in a pressurized chamber) helps with long COVID symptoms, especially brain fog and thinking problems. It may be an option if you have had lingering symptoms for at least 2 months and can travel to one of the study sites.
Toronto, OntarioAges 18 years+
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Common questions
- Are there clinical trials for symptom?
- Yes. Clin2 currently lists 909 recruiting symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.