Clinical trials
Symptom clinical trials
Below are recruiting symptom clinical trials, each written for real people, not researchers. We’re tracking 912 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT06684470RecruitingEarly Phase 1
Combining a low-FODMAP diet with medication for IBS-D
This trial tests if a special diet (low-FODMAP) combined with a medication (mirtazapine) can improve IBS with diarrhea symptoms. It is for adults who have not tried these treatments before.
Jacksonville, FloridaAges 18–70 - NCT06683378RecruitingPhase 1
Parkinson's study: nerve implant during DBS surgery
This trial tests if implanting a small piece of your own leg nerve into the brain can improve Parkinson's symptoms. It is done at the same time as deep brain stimulation (DBS) surgery.
Lexington, KentuckyAges 45–75 - NCT06687603Recruiting
Detecting Barrett's esophagus in people without heartburn
This study aims to screen for Barrett's esophagus in people who are getting a routine colonoscopy but do not have chronic heartburn. It uses a simple, non-invasive cell collection device (EsoCheck) to see if you might have Barrett's esophagus, which can increase the risk of esophageal cancer.
Aurora, ColoradoAges 50 years+ - NCT06674252Recruiting
Herbal treatment for symptoms after lung cancer surgery
This study tests whether a modified herbal formula (Bufei Decoction) can help reduce symptoms like cough, fatigue, and shortness of breath in older adults after lung cancer surgery, and whether it improves survival.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT06390462Recruiting
Counseling for teens in school-based primary care
This study tests a brief counseling approach called Interpersonal Counseling for Adolescents (IPC-A) in school settings. It aims to help teens with emotional or social challenges before they become more serious, and it's designed for those who aren't already in mental health treatment.
HämeenlinnaAges 13–16 - NCT06650813Recruiting
Adapting a fatigue program for sickle cell disease
This trial adapts the FACETS program, a fatigue-management course, for people with sickle cell disease. It aims to help participants better cope with fatigue and improve daily life.
GrenobleAges 18 years+ - NCT06655337Recruiting
Testing a smartphone app for managing hospital discharge
This study tests whether a smartphone app called Medidux helps you manage your symptoms and discharge from the hospital if you came in with coughing, back pain, or belly discomfort. You'll use the app to report how you're feeling, and the care team can check in with you after you leave.
Horgen, Canton of ZurichAges 18 years+ - NCT06653426Recruiting
The effect of NaBu on menstrual symptoms
This study tests whether taking a supplement called NaBu can help reduce menstrual symptoms. It may be an option if you have bothersome period symptoms like cramps or bloating.
Chicago, IllinoisAges 18 years+ - NCT06642519Enrolling by invitation
Brain-computer interface for freezing of gait in Parkinson's
This study tests a brain-computer interface device to help people with Parkinson's disease who experience freezing of gait. The goal is to see if the device can reduce freezing episodes when medication isn't enough.
Toronto, OntarioAges Any age - NCT06633263Enrolling by invitation
Combined therapy for depression and insomnia
This trial tests a combination of two behavioral therapies to improve both depression symptoms and sleep problems. It may help you if you have moderate depression and insomnia and can participate in French-language sessions.
LiègeAges 18–67 - NCT06642454Enrolling by invitation
Breathing-guided nerve stimulation for Parkinson's disease
This study tests a type of nerve stimulation (vagus nerve) for Parkinson's disease. It compares a method that uses your breathing cycle to deliver stimulation versus standard stimulation. The goal is to see which works better for movement and non-movement symptoms.
Hefei, AnhuiAges 40–80 - NCT06642675Recruiting
Brain stimulation for negative symptoms in schizophrenia
This trial tests whether a non-invasive brain stimulation technique called nTMS (repetitive transcranial magnetic stimulation) can help reduce negative symptoms of schizophrenia, like lack of motivation or social withdrawal. It's a possible treatment option for people with stable schizophrenia who still struggle with these symptoms.
Changsha, HunanAges Up to 60 years - NCT05762952RecruitingPhase 1
Dapagliflozin study for heart micro-blood-flow symptoms in women
This early-phase study tests whether dapagliflozin can improve tiny blood-vessel function in women who have heart-ache-like symptoms but no major blockage on heart scans. If it works, it may help symptoms related to “microvascular” heart circulation problems.
Charlottesville, VirginiaAges 18–99 - NCT06631287RecruitingPhase 3
Testing baricitinib for persistent long COVID symptoms
This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.
Tucson, ArizonaAges 18 years+ - NCT06626425Recruiting
Well-being training for teens with depression
This study tests a 4-week well-being training program to see if it helps teens feel better and manage depression. You would use a smartphone app and answer surveys to track your mood and well-being.
Madison, WisconsinAges 14–19 - NCT06613438Recruiting
New wearable device for GERD symptoms
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
Chicago, IllinoisAges 22–75 - NCT06601998Recruiting
Heart health after severe pneumonia
This study looks at how heart health changes in people who have recovered from severe pneumonia, including COVID-19. It compares survivors to healthy people and those with heart risk factors.
AlexandroupoliAges 18 years+ - NCT06604520RecruitingPhase 2
Vortioxetine for mood and thinking in frontotemporal dementia
This trial tests if vortioxetine, an antidepressant, can improve mood symptoms (like depression or anxiety) and thinking abilities in people with frontotemporal dementia (FTD). It also includes healthy volunteers for comparison.
Baltimore, MarylandAges 45 years+ - NCT06607523Recruiting
Prebiotic treatment for brain injury recovery
This study tests whether a prebiotic (a type of fiber that feeds healthy gut bacteria) can improve recovery from a brain injury by helping the connection between the gut and the brain. Participants include people with a recent brain injury and their family members or staff, all of whom are part of the Moody Neurorehabilitation Institute community.
Galveston, TexasAges 18 years+ - NCT06608849Recruiting
Long-term health effects after COVID-19
This study looks at how COVID-19 may affect the lungs, heart, and kidneys in the months or years after the infection. It compares three groups: people who never had COVID, people who had COVID but recovered without organ problems, and people who had organ problems during COVID. The goal is to understand what long-term complications might arise.
AthensAges 18 years+ - NCT06612294Recruiting
Asthma symptom perception study for older adults
This study looks at how older adults with asthma perceive their symptoms. It aims to improve understanding of asthma symptoms in people over 60 with uncontrolled asthma.
New York, New YorkAges 60 years+ - NCT06615453Recruiting
Tixel treatment for dry eye disease and periorbital wrinkles
This study tests a device called Tixel that may help reduce wrinkles around the eyes and improve dry eye symptoms. If you have mild to moderate under-eye wrinkles and dry eyes that bother you a lot, this treatment might be an option.
BirminghamAges 18 years+
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Common questions
- Are there clinical trials for symptom?
- Yes. Clin2 currently lists 912 recruiting symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.