Clinical trials
Syncope clinical trials
Below are recruiting syncope clinical trials, each written for real people, not researchers. We’re tracking 35 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05755737RecruitingPhase 2
Ondansetron to prevent fainting episodes from vasovagal syncope
This Phase 2 study tests whether ondansetron can help prevent future fainting (vasovagal syncope) in adults who have had recent episodes. If it works, it may reduce how often you faint and improve safety in everyday situations.
Calgary, AlbertaAges 18–100 - NCT06356207Recruiting
Measuring heart pause time in fainting during tilt table test
This study tests a new way to measure how long it takes for your heart to pause during a tilt table test, in people with reflex fainting spells. The results may help doctors decide if a pacemaker is right for you.
BolzanoAges 18 years+ - NCT07775976Enrolling by invitation
Whole-heart checkup with a wearable heart monitor
This study looks at how well a wearable heart monitor and special software can check the health of your whole heart and assess your risk of future heart problems. It may help doctors create more personalized care plans.
Pasadena, CaliforniaAges 18 years+ - NCT05776810Recruiting
Check why fainting happens using tilt tests or heart tracing
This study looks at people who have had repeated fainting spells and still don’t know the cause. It tests whether different types of heart monitoring (like tilt testing or an ECG/heart tracing) can better explain what’s triggering syncope and guide prevention.
Calgary, AlbertaAges 50–110 - NCT04755101Recruiting
Right-sided ablation for fainting caused by heart nerve signals
This trial studies a procedure that targets a specific heart nerve area on the right side to reduce neurally mediated fainting (syncope). You may be a candidate if your fainting is linked to heart rhythm/nerve reflexes and you meet several heart-function and heart-rhythm test criteria.
BonheidenAges 14 years+ - NCT05855603Recruiting
Pacemaker versus nerve ablation for fainting due to slow heart rate
This trial studies treatments for a type of fainting caused by the body’s reflex slowing the heart. It compares a permanent pacemaker with a procedure called cardiac nerve ablation to see which helps prevent fainting and improves quality of life.
Sant Joan d'Alacant, AlicanteAges 40 years+ - NCT05159687RecruitingPhase 3
Atomoxetine to help prevent fainting from vasovagal episodes
This Phase 3 study tests whether atomoxetine can reduce how often vasovagal fainting happens. It may help people who have frequent fainting episodes with triggers like stress or standing for long periods.
Calgary, AlbertaAges 18 years+ - NCT07502599Recruiting
Fainting detection and early warning in syncope study
This study tests a new way to detect and warn about fainting in people with certain types of syncope (temporary loss of consciousness). It may help those who have already had a specific fainting evaluation called an ARS assessment.
Rochester, MinnesotaAges 18 years+ - NCT07459478Recruiting
Tilt-table test for vasovagal fainting
This study looks at whether using a tilt-table (a special table that tilts you upright to trigger fainting) helps doctors better understand and treat fainting caused by vasovagal syncope. If you have this type of fainting, this study could help find better ways to manage it.
AmsterdamAges 18 years+ - NCT04972071Recruiting
Using a heart-related fainting risk score in emergency care
This trial helps emergency departments use a simple risk score to guide care for adults who faint. It looks at whether using these recommended steps improves how syncope (fainting) is assessed and managed in the ER.
Calgary, AlbertaAges 18 years+ - NCT06159764Recruiting
Registry of nerve-targeting heart treatment for fainting
This registry tracks people who receive a heart procedure called cardioneuroablation to stop severe fainting spells. The procedure targets nerve signals that cause the heart to pause, and researchers want to learn how well it works in real-world patients.
BronAges 18–100 - NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT06472375Recruiting
24-hour observation after fainting in the hospital
This study looks at whether people who come to the hospital after a fainting spell can be safely watched for 24 hours inside the hospital, instead of being admitted for a longer stay. It may help doctors decide the best way to monitor low- and intermediate-risk fainting.
AmsterdamAges 18 years+ - NCT06166277Recruiting
Ablation for fainting and slow heartbeat registry
This study tests a procedure called cardioneuroablation for people whose fainting or very slow heartbeat doesn't improve with other treatments. If you are under 60, have no other major heart conditions, and have not had ablation before, it might be an option to reduce or stop your fainting spells.
Chicago, IllinoisAges 18–60 - NCT05633693Recruiting
Exercises to help children with fainting and blood-pressure drops
This study tests whether teaching special standing/balance movements can reduce fainting episodes in children who have recurring vasovagal fainting or certain forms of POTS. It may help your child feel more stable when standing and improve symptoms, while researchers measure balance and “counterpressure” responses during the tests.
Burnaby, British ColumbiaAges 6–18 - NCT05621460Recruiting
Water carbonation and how well you tolerate standing up
This study tests whether drinking carbonated (fizzy) water changes how well your body handles standing up without feeling faint. If you are healthy and don’t have certain heart or nerve problems, you may be able to take part.
Burnaby, British ColumbiaAges 19–50 - NCT05555771Recruiting
Kids with fainting episodes after arriving at the emergency room
This study looks at children and teens (ages 6–18) who recently fainted but are now back to normal, using a survey. It aims to better understand fainting episodes that happen before the emergency visit and how to evaluate them safely.
Vancouver, British ColumbiaAges 6–18 - NCT05066347Recruiting
Remote heart monitoring after fainting discharge from the ER
This trial studies whether remote heart monitoring after an ER visit for fainting (syncope) can help identify dangerous heart problems. You may be enrolled only if your fainting episode seems medium- to high-risk and you’re being sent home from the ER.
Ottawa, OntarioAges 18 years+ - NCT03360227Recruiting
Registry after heart device implantation planning
This is a registry study that records information from people before they get a heart-related device implanted. It may help doctors understand how the team’s tests and planning relate to the procedure and outcomes later on.
DüsseldorfAges 18–80 - NCT05752682Recruiting
Check care for fainting or falls in adults over 40
This trial tests a “global” approach to assessing episodes of fainting or falling in people age 40 and older. It may help doctors find the right cause and safer next steps after an episode.
Milan, MIAges 40 years+ - NCT05896592Recruiting
Ablation versus changing pacing settings for slow heartbeats
This study compares a procedure called cardioneuroablation with staying on permanent pacing in people who have symptoms from a slow heart rate. It aims to see which approach works better and is safer for reducing symptoms related to sinus node or heart conduction problems.
Radom, Masovian VoivodeshipAges 18–65 - NCT06288633Recruiting
Heart nerve ablation for slow heart rhythm
This test uses a procedure to ablate (destroy) specific nerves in the heart that may be causing your heart to beat too slowly. The goal is to help your heart speed up naturally when needed, so you may avoid needing a permanent pacemaker.
Saint PetersburgAges 18–65 - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT07671898Recruiting
Freezing vs. Radiofrequency for Slow Heart Rate
This trial compares two procedures to treat very slow heart rates without needing a pacemaker. One uses freezing (cryoablation) and the other uses radiofrequency energy to target nerves that control heart rate.
Tomsk, Tomsk OblastAges 18–60
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Common questions
- Are there clinical trials for syncope?
- Yes. Clin2 currently lists 35 recruiting syncope studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a syncope trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a syncope trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.