Clinical trials
Syncope clinical trials
Below are recruiting syncope clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05755737RecruitingPhase 2
Ondansetron to prevent fainting episodes from vasovagal syncope
This Phase 2 study tests whether ondansetron can help prevent future fainting (vasovagal syncope) in adults who have had recent episodes. If it works, it may reduce how often you faint and improve safety in everyday situations.
Calgary, AlbertaAges 18–100 - NCT04755101Recruiting
Right-sided ablation for fainting caused by heart nerve signals
This trial studies a procedure that targets a specific heart nerve area on the right side to reduce neurally mediated fainting (syncope). You may be a candidate if your fainting is linked to heart rhythm/nerve reflexes and you meet several heart-function and heart-rhythm test criteria.
BonheidenAges 14 years+ - NCT05776810Recruiting
Check why fainting happens using tilt tests or heart tracing
This study looks at people who have had repeated fainting spells and still don’t know the cause. It tests whether different types of heart monitoring (like tilt testing or an ECG/heart tracing) can better explain what’s triggering syncope and guide prevention.
Calgary, AlbertaAges 50–110 - NCT06356207Recruiting
Measuring heart pause time in fainting during tilt table test
This study tests a new way to measure how long it takes for your heart to pause during a tilt table test, in people with reflex fainting spells. The results may help doctors decide if a pacemaker is right for you.
BolzanoAges 18 years+ - NCT07502599Recruiting
Fainting detection and early warning in syncope study
This study tests a new way to detect and warn about fainting in people with certain types of syncope (temporary loss of consciousness). It may help those who have already had a specific fainting evaluation called an ARS assessment.
Rochester, MinnesotaAges 18 years+ - NCT04972071Recruiting
Using a heart-related fainting risk score in emergency care
This trial helps emergency departments use a simple risk score to guide care for adults who faint. It looks at whether using these recommended steps improves how syncope (fainting) is assessed and managed in the ER.
Calgary, AlbertaAges 18 years+ - NCT05066347Recruiting
Remote heart monitoring after fainting discharge from the ER
This trial studies whether remote heart monitoring after an ER visit for fainting (syncope) can help identify dangerous heart problems. You may be enrolled only if your fainting episode seems medium- to high-risk and you’re being sent home from the ER.
Ottawa, OntarioAges 18 years+ - NCT05159687RecruitingPhase 3
Atomoxetine to help prevent fainting from vasovagal episodes
This Phase 3 study tests whether atomoxetine can reduce how often vasovagal fainting happens. It may help people who have frequent fainting episodes with triggers like stress or standing for long periods.
Calgary, AlbertaAges 18 years+ - NCT05555771Recruiting
Kids with fainting episodes after arriving at the emergency room
This study looks at children and teens (ages 6–18) who recently fainted but are now back to normal, using a survey. It aims to better understand fainting episodes that happen before the emergency visit and how to evaluate them safely.
Vancouver, British ColumbiaAges 6–18 - NCT05621460Recruiting
Water carbonation and how well you tolerate standing up
This study tests whether drinking carbonated (fizzy) water changes how well your body handles standing up without feeling faint. If you are healthy and don’t have certain heart or nerve problems, you may be able to take part.
Burnaby, British ColumbiaAges 19–50 - NCT05633693Recruiting
Exercises to help children with fainting and blood-pressure drops
This study tests whether teaching special standing/balance movements can reduce fainting episodes in children who have recurring vasovagal fainting or certain forms of POTS. It may help your child feel more stable when standing and improve symptoms, while researchers measure balance and “counterpressure” responses during the tests.
Burnaby, British ColumbiaAges 6–18 - NCT05855603Recruiting
Pacemaker versus nerve ablation for fainting due to slow heart rate
This trial studies treatments for a type of fainting caused by the body’s reflex slowing the heart. It compares a permanent pacemaker with a procedure called cardiac nerve ablation to see which helps prevent fainting and improves quality of life.
Sant Joan d'Alacant, AlicanteAges 40 years+ - NCT06159764Recruiting
Registry of nerve-targeting heart treatment for fainting
This registry tracks people who receive a heart procedure called cardioneuroablation to stop severe fainting spells. The procedure targets nerve signals that cause the heart to pause, and researchers want to learn how well it works in real-world patients.
BronAges 18–100 - NCT06166277Recruiting
Ablation for fainting and slow heartbeat registry
This study tests a procedure called cardioneuroablation for people whose fainting or very slow heartbeat doesn't improve with other treatments. If you are under 60, have no other major heart conditions, and have not had ablation before, it might be an option to reduce or stop your fainting spells.
Chicago, IllinoisAges 18–60 - NCT06440291Recruiting
Nerve treatment for fainting and exercise ability
This study tests if a procedure called cardioneuroablation can help people who faint or feel like they're about to faint due to a slow heart rate. The treatment targets the nerves around the heart to improve heart rate control and exercise capacity.
WarsawAges Any age - NCT06472375Recruiting
24-hour observation after fainting in the hospital
This study looks at whether people who come to the hospital after a fainting spell can be safely watched for 24 hours inside the hospital, instead of being admitted for a longer stay. It may help doctors decide the best way to monitor low- and intermediate-risk fainting.
AmsterdamAges 18 years+ - NCT06513650Recruiting
Treating fainting caused by low blood pressure
This trial tests if adjusting blood pressure medicines or adding a new medicine (fludrocortisone) can reduce fainting episodes in people who have severe reflex syncope that hasn't improved with lifestyle changes.
MarseilleAges 18 years+ - NCT07459478Recruiting
Tilt-table test for vasovagal fainting
This study looks at whether using a tilt-table (a special table that tilts you upright to trigger fainting) helps doctors better understand and treat fainting caused by vasovagal syncope. If you have this type of fainting, this study could help find better ways to manage it.
AmsterdamAges 18 years+ - NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT03446326Recruiting
Check how your pacemaker changes heart pumping
This study measures how well the heart pumps at different heart rates in people with pacemakers or defibrillators. It may help doctors understand how pacing settings affect heart function.
Calgary, AlbertaAges 18–70 - NCT04075084Recruiting
Watching outcomes of routine home monitoring after a heart monitor implant
This registry study follows people who get a BIOTRONIK implantable heart monitor and use home monitoring. It looks at how routine care and at-home check-ins work in real life, which may help improve support and tracking over time.
AdelaideAges 18 years+ - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT05493605Recruiting
MRI study of heart involvement in Wilson disease
This study looks at whether Wilson disease affects the heart, using MRI scans (and possibly contrast dye). Your results may help doctors better understand cardiac (heart) involvement and how it progresses in Wilson disease.
ParisAges 18 years+ - NCT05752682Recruiting
Check care for fainting or falls in adults over 40
This trial tests a “global” approach to assessing episodes of fainting or falling in people age 40 and older. It may help doctors find the right cause and safer next steps after an episode.
Milan, MIAges 40 years+
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Common questions
- Are there clinical trials for syncope?
- Yes. Clin2 currently lists 37 recruiting syncope studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a syncope trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a syncope trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.