Clinical trials
Therapy clinical trials
Below are recruiting therapy clinical trials, each written for real people, not researchers. We’re tracking 7,177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05498792RecruitingEarly Phase 1
Trial testing CBL0137 with two immunotherapy drugs for melanoma
This early trial tests CBL0137 along with ipilimumab and nivolumab (two immune-based cancer medicines) in people with stage III or possibly stage IV melanoma that can be biopsied. It may help shrink melanoma and improve immune control, while also learning how safe and effective this combination is.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05495633Recruiting
Tracking outcomes after Rezum treatment for prostate blockage
This trial is collecting information about how well Rezum water-vapor treatment works for men with prostate blockage and urinary symptoms. It’s mainly focused on whether different kinds of patients do well, using surveys and clinic follow-up, not on changing your treatment plan.
GrazAges 18 years+ - NCT05464888Recruiting
Animal-assisted therapy for kids’ dental visits
This study tests whether working with a trained animal can make dental checkups and cleanings easier for children ages 4 to 8. It may help reduce fear and improve how kids tolerate routine dental care.
Chapel Hill, North CarolinaAges 4–8 - NCT03567889RecruitingPhase 3
Injectable treatment before surgery for advanced melanoma
This trial tests whether an injected medicine placed directly into melanoma tumors before surgery can improve outcomes for melanoma that has spread to nearby lymph nodes/skin but can still be fully removed. It aims to shrink the cancer and reduce the chance it comes back after surgery.
Phoenix, ArizonaAges 18 years+ - NCT05440617Recruiting
Biobank for people having testicle-protecting cancer treatment
This study collects and stores biological samples from people who are planning to undergo OTC, a treatment used to help protect fertility during cancer therapy that can harm reproductive cells. It may help future research by providing researchers with tissue/blood samples linked to this treatment.
Bethesda, MarylandAges 4–35 - NCT05440214Recruiting
Therapy to reduce suicide risk in people with psychosis
This trial tests an approach aimed at emotional ups-and-downs to help lower suicide risk in people who have psychosis and are at higher risk for suicidal thoughts or behaviors. If you qualify, you would get outpatient mental health care while participating in the study.
Baltimore, MarylandAges 18 years+ - NCT05458947Recruiting
Physical therapy wound treatments for spinal cord injury sores
This study tests different physical therapy approaches to help heal pressure sores on the sacrum or ischium in people with a spinal cord injury. You may be able to join if you’re already in inpatient rehabilitation and your wound severity score fits the study criteria.
Charlotte, North CarolinaAges 18 years+ - NCT05448547RecruitingPhase 3
Tested curative vs conservative treatment for older men with high-risk prostate cancer
This Phase 3 study compares an immediate curative treatment plan versus a more conservative approach in men age 75 and older with newly diagnosed, high-risk prostate cancer. The goal is to see which strategy controls the cancer while better protecting quality of life.
CopenhagenAges 75 years+ - NCT05457049Recruiting
Skip extra treatment for early lung cancer after surgery if no cancer found
This study checks if people with early-stage non-small cell lung cancer can safely skip chemotherapy or radiation after surgery when repeated blood tests show no sign of cancer left. You would only be watched with regular scans and blood tests to make sure the cancer doesn't come back.
Foshan, GuangdongAges 18 years+ - NCT05429970Recruiting
Reducing stress before ovarian cancer surgery with two medicines
This study tests whether giving two commonly used medicines before surgery—one that can lower stress on the body (a beta-blocker) and one that reduces inflammation (a COX-2 inhibitor)—can improve outcomes compared with standard care. It’s for people with advanced ovarian, fallopian tube, or primary peritoneal cancer who are having open surgery.
Basking Ridge, New JerseyAges 18 years+ - NCT05443087Recruiting
Checking blood levels of targeted drugs for digestive cancers
This trial monitors how your prescribed targeted cancer medicine moves through your body by doing extra blood tests. The goal is to understand the drug’s levels and dosing in people with advanced digestive cancers, so treatment can be better managed.
AmiensAges 18 years+ - NCT05423444Recruiting
Therapy for PTSD in teens using brain connectivity imaging
This study looks at how well PTSD-focused therapy changes brain “connectivity” patterns in adolescents. It may help your care team understand which teens benefit most from therapy.
San Antonio, TexasAges 12–17 - NCT05423210RecruitingEarly Phase 1
Atezolizumab with pre-surgery brain radiation for glioblastoma
This early-phase study tests atezolizumab (an immune therapy) together with radiation before brain surgery for glioblastoma. It aims to make the treatment safer and more effective before the tumor is removed.
Stony Brook, New YorkAges 18 years+ - NCT05418556RecruitingPhase 4
Comparing antiplatelet strategies after heart stent
This study compares two ways of choosing blood thinners after a heart stent procedure. It aims to see if using an imaging-guided strategy leads to better outcomes than usual care.
Bucheon-siAges 19 years+ - NCT05443425RecruitingPhase 1
Leflunomide plus steroids for acute graft-versus-host disease
This early-phase trial tests whether adding leflunomide to standard steroid treatment can better control acute graft-versus-host disease (aGvHD) after a stem cell transplant. It may help reduce the immune reaction that damages the body while keeping treatment safe and manageable.
Duarte, CaliforniaAges 18 years+ - NCT05431010Recruiting
Electroacupuncture for walking problems in older people with muscle loss
This study tests whether electroacupuncture (a type of acupuncture that uses a mild electric current) can improve walking ability in older adults with sarcopenia, which means age-related loss of muscle. If it helps, it could make it easier to walk and complete daily activities.
Hangzhou, ZhejiangAges 60–95 - NCT05430698RecruitingPhase 2
PD-1 antibody after surgery for bile duct cancer
This Phase 2 trial studies whether adding a PD-1 antibody plus gemcitabine/oxaliplatin (GEMOX) after surgery can lower the chance of the cancer coming back in perihilar cholangiocarcinoma. It’s for people who have had surgery with no tumor left at the cut edges, but lymph nodes showed cancer under the microscope.
Guangzhou, GuangdongAges 18–75 - NCT05429983Recruiting
Predicts results from Inspire tongue-stimulation for sleep apnea
This study looks at how breathing mechanics during a sleep-related test (DISE) can help predict how well Inspire tongue (hypoglossal nerve) stimulation will work. It may help your care team choose the best approach and set expectations for improvement.
Baltimore, MarylandAges 18 years+ - NCT05435495Recruiting
Study why PSMA radioligand therapy stops working
This study looks at tissue samples from tumors to understand how and why PSMA radioligand therapy may become less effective. If you have PSMA-avid cancer lesions that can be biopsied, the trial may help researchers find ways to improve treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT04146376Recruiting
Study of medicines for Von Willebrand disease during pregnancy
This study looks at how well a Von Willebrand disease treatment plan works during pregnancy, and whether some patients need extra “adjusting” of medicine. It may help prevent bleeding problems by matching treatment to each person’s lab results later in pregnancy.
Aurora, ColoradoAges 18 years+ - NCT04966663RecruitingPhase 2
Using blood DNA tests to guide lung cancer treatment
This study uses a blood test called ctDNA to look for leftover lung cancer after surgery. Based on that result, the trial will help decide which treatment approach is best for you and may catch cancer returning earlier.
Toronto, OntarioAges 18 years+ - NCT05134779Recruiting
Study aims to tailor cancer treatment to your biology
This study looks at how genes, the cancer environment, and your immune system interact to develop treatments that work better for people with breast cancer. It may help researchers learn why some treatments work for certain people and not others.
New York, New YorkAges 18–90 - NCT05371808Recruiting
Early vs delayed treatment for high-risk CLL: cost study
This study compares early treatment versus delaying treatment in newly diagnosed people with high-risk CLL/SLL who feel well. It mainly looks at the overall “costs and value” of each approach and asks patients to complete short health and quality-of-life questionnaires.
Vancouver, British ColumbiaAges 18 years+ - NCT05382338RecruitingPhase 3
Sodium thiosulfate to protect hearing in medulloblastoma
This Phase 3 study tests whether adding sodium thiosulfate during treatment for newly diagnosed medulloblastoma can reduce the risk of hearing loss. It is designed for children and teens whose cancer meets specific low-risk or average-risk tumor and lab features.
Birmingham, AlabamaAges 4–21
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Common questions
- Are there clinical trials for therapy?
- Yes. Clin2 currently lists 7,177 recruiting therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.