Clinical trials
Therapy clinical trials
Below are recruiting therapy clinical trials, each written for real people, not researchers. We’re tracking 7,177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03522064RecruitingPhase 2
HRD-positive advanced prostate cancer trial with androgen therapy and chemo
This Phase 2 study tests whether blocking male hormones (androgen therapy) plus the chemotherapy drug carboplatin can shrink advanced prostate cancer in men with specific DNA repair problems. It is for cases where prostate-specific antigen (PSA) is rising even though testosterone is already kept very low.
Sydney, New South WalesAges 18 years+ - NCT03680677Recruiting
Checking frailty to guide treatment in older blood cancer patients
This study checks “frailty” (how strong and able you are to function) to help choose better treatment for people age 60+ with certain blood cancers like acute leukemia or MDS. It may help clinicians tailor care before major treatments like transplant or CAR T-cell therapy.
Philadelphia, PennsylvaniaAges 60 years+ - NCT03713203Recruiting
Light-based treatment for vulvar Paget’s disease
This study tests a special light treatment (photodynamic therapy) for non-invasive Paget’s disease on the vulva that has come back after surgery. It may help by treating remaining abnormal skin cells where surgery may not remove everything.
LilleAges 18 years+ - NCT03516708RecruitingPhase 1/Phase 2
Epacadostat with pre-op radiation for locally advanced rectal cancer
This trial studies whether adding epacadostat (a cancer drug) to standard pre-operative chemoradiation can improve outcomes for people with locally advanced rectal cancer. It’s designed to see if the added treatment is safe and potentially more effective before surgery.
Orange, CaliforniaAges 18 years+ - NCT03321045RecruitingEarly Phase 1
PET scan to predict benefit from HER2-targeted breast cancer therapy
This early-phase study uses a special PET scan with a drug tagged for imaging to predict how well HER2-targeted treatments will work. It may help doctors choose the most effective therapy for HER2-positive breast cancer.
Birmingham, AlabamaAges 18 years+ - NCT03435796RecruitingPhase 2/Phase 3
Follow-up for people treated with gene-modified T cells
This study is a long-term check-in for people who previously received gene-modified T-cell infusions in a related Celgene/Juno/BMS trial. It helps researchers track safety and long-term effects over time.
Birmingham, AlabamaAges Any age - NCT03463954Recruiting
Laser treatment trial for small breast tumors
This trial tests a focused laser treatment (Novilase®) to destroy small, cancerous breast tumors while aiming to work with standard care. It may help people who have an early, localized tumor that can be clearly seen on imaging so doctors can guide the laser safely.
Duarte, CaliforniaAges 18 years+ - NCT03369353Enrolling by invitation
Personalized immune testing study for bowel and transplant patients
This study looks at whether a precise lab test can help understand inflammatory bowel disease, functional gut disorders, and immune changes after stem cell transplant or cell therapy. It may help doctors choose better monitoring and treatments based on your immune and gut test results.
Boston, MassachusettsAges Any age - NCT03509558Recruiting
Tapping a device on the back plus leg exercise for walking
This study tests whether a device placed on the back can help improve leg movement and walking ability after a spinal cord injury. It combines the device with supervised physical therapy over many weeks to see if it helps with daily mobility.
Seattle, WashingtonAges 21–70 - NCT03340129RecruitingPhase 2
Nivolumab plus focused brain radiation for melanoma spread
This trial studies whether giving the immunotherapy drug nivolumab together with targeted brain radiation (not whole-brain radiation) helps people with melanoma that has spread to the brain. It aims to improve brain control while keeping side effects manageable.
Sydney, New South WalesAges 18–120 - NCT03378102RecruitingEarly Phase 1
AdV-targeted T cells for adenovirus after bone marrow transplant
This trial tests a custom immune cell treatment (T cells made to recognize adenovirus) for people whose adenovirus infection is not improving or who cannot tolerate standard antiviral medicines after a bone marrow transplant. It aims to help your body control the virus and prevent organ complications.
Cleveland, OhioAges 3 months+ - NCT03472157Recruiting
Bariatric surgery for severe NASH with advanced liver scarring
This study tests whether bariatric surgery (either sleeve gastrectomy or Roux-en-Y gastric bypass) improves severe nonalcoholic steatohepatitis (NASH) with advanced liver scarring in people who are obese. You may also need liver biopsies to confirm your liver disease before and after treatment.
LilleAges 18–65 - NCT03353584Recruiting
Virtual reality for pain relief during sickle cell pain crises
This trial tests whether a virtual reality (VR) experience can help reduce pain during a sickle cell “vaso-occlusive crisis,” which is an episode of sudden, severe pain. It’s offered alongside the care team’s usual pain management to see if VR makes pain feel better.
Memphis, TennesseeAges 6–25 - NCT03425526RecruitingPhase 1
Donor T-cell treatment for adenovirus illness in immune-weakened people
This early-phase study tests donor immune cells (T cells) to treat people who have adenovirus infection or adenovirus-related disease but have a weakened immune system. It may help your body fight the virus, especially in cases where other treatments may not be enough.
Houston, TexasAges Any age - NCT03109288RecruitingPhase 1/Phase 2
Biomarker-guided combination treatment for residual multiple sclerosis activity
This early-phase study tests combination treatments for multiple sclerosis (MS) based on lab “biomarkers” found in the spinal fluid. It aims to reduce ongoing MS activity and help determine which treatment combinations may work best for different people.
Bethesda, MarylandAges 18–120 - NCT03226704Enrolling by invitation
Leukapheresis to prepare CAR cell therapy
This trial collects white blood cells through a procedure called leukapheresis to help make CAR or other adoptive cell therapies. It’s for people with certain cancers who are not in remission (or are at high risk of relapse) and can meet health and lab requirements.
Bethesda, MarylandAges 3–65 - NCT03167437RecruitingPhase 1/Phase 2
Vorinostat for uncontrolled Crohn’s or ulcerative colitis
This early-phase study tests vorinostat to reduce gut inflammation in people with moderate-to-severe Crohn’s disease, ulcerative colitis, or certain colitis patterns linked to chronic granulomatous disease (CGD). It also looks at whether the study’s consent process is clear and understood before starting treatment.
Bethesda, MarylandAges 18–65 - NCT03206060RecruitingPhase 2
Lu-177 DOTATATE for hard-to-remove pheochromocytoma or paraganglioma
This trial studies Lu-177 DOTATATE (Lutathera), a targeted radiation medicine, for tumors that cannot be safely removed with surgery. It aims to shrink or control pheochromocytoma/paraganglioma that is showing recent growth and has a specific target signal on a special PET scan.
Bethesda, MarylandAges 18–100 - NCT03254667Enrolling by invitation
Track outcomes in adults with moderate-to-severe psoriasis
This study keeps track of how people with moderate-to-severe psoriasis do over time while using Siliq or other approved treatments. It may help researchers understand how treatments compare in real life.
Bridgewater, New JerseyAges 18–99 - NCT03167203Enrolling by invitationPhase 1/Phase 2
Safety check after stem-cell eye treatment
This study follows people who previously received an embryonic stem-cell–derived treatment for macular (central) vision loss. Its goal is to watch for long-term side effects and better understand how safe the treatment is over time.
Kansas City, MissouriAges 18 years+ - NCT03209583Recruiting
Test of fast-pacing therapy for congenital heart rhythm issues
This trial studies whether a device-based fast pacing therapy (called ATP) can better treat certain rapid heart rhythm problems in people born with a heart condition. It may help prevent or reduce episodes of atrial (upper-chamber) arrhythmias that occur despite having a pacing/defibrillator device.
Los Angeles, CaliforniaAges Any age - NCT03161522RecruitingPhase 2
Chemo alone versus with radiation or surgery for limited spread
This study tests whether adding radiation or surgery to chemotherapy can improve outcomes for people whose esophageal or stomach cancer has spread to only a few places. If your cancer is “oligometastatic” (up to 3 spots), the trial helps doctors see which approach gives the best control.
Houston, TexasAges 18–79 - NCT03184038Recruiting
Testing brain function in people with brain metastases after radiosurgery
This study looks at how well your thinking and memory work after treatment with radiosurgery for brain metastases. It may help researchers understand which patients benefit best and how to monitor side effects on brain function.
Sewell, New JerseyAges 18 years+ - NCT03279094RecruitingPhase 1
Testing a half-matched bone marrow transplant for sickle cell
This early-phase study tests whether a “half-matched” donor bone marrow transplant, with special medicines to calm the immune system before transplant, can improve outcomes for people with sickle cell disease. It may help high-risk patients who have frequent complications and don’t have a fully matched donor.
Duarte, CaliforniaAges 1–30
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Common questions
- Are there clinical trials for therapy?
- Yes. Clin2 currently lists 7,177 recruiting therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.