Clinical trials
Tobacco Smoking clinical trials
Below are recruiting tobacco smoking clinical trials, each written for real people, not researchers. We’re tracking 125 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07489443Recruiting
Helping pregnant women reduce tobacco and cannabis use
This study is testing a program to help pregnant women and new mothers cut back on or quit using tobacco and cannabis. It’s designed to see if the program is easy to use and helps improve health for both mom and baby.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07568483Recruiting
Web-based smoking cessation support program
This study tests TUBSIS 2.0, a digital program designed to help you quit or cut back on smoking. You'll use it on your computer, tablet, or phone, and researchers will track how it affects your smoking habits over time.
ZurichAges 18 years+ - NCT07236580Recruiting
Breathing exercises for teens with ear problems and smoke exposure
This study tests whether special breathing exercises can help teenagers with a blocked eustachian tube (the tube that connects the ear to the throat) whose parents smoke. It aims to improve ear and lung function.
Giza, DokkiAges 13–17 - NCT05852860Enrolling by invitation
Mentoring program for HIV clinicians on tobacco cessation
This study tests a mentoring program to help clinicians who care for HIV patients learn more about helping patients quit smoking. It aims to improve how doctors and nurses support tobacco cessation in HIV care.
Philadelphia, PennsylvaniaAges Any age - NCT07162935Recruiting
Cigarillo use study for young adults
This study looks at how young adults use cigarillos. You will smoke research cigarillos in a lab and answer questions. The goal is to understand cigarillo use to help with future regulation.
Oklahoma City, OklahomaAges 18–24 - NCT07441603Recruiting
Lifestyle support program for hospital patients
This trial tests a proactive lifestyle program for patients admitted to the hospital. It aims to help you improve your health habits during your stay.
GreifswaldAges 18–64 - NCT06930547Recruiting
Smoking cessation education for recovery
This study tests whether education classes can help people who are in recovery from mental health issues quit smoking. It is for people registered with a Community Mental Health Center who smoke daily.
Erzurum, ErzurumAges 18 years+ - NCT05999383RecruitingPhase 2
Marijuana and tobacco use study
This trial looks at how marijuana and tobacco work together in your body. If you regularly use both cannabis and tobacco, you may help researchers understand their combined effects.
San Francisco, CaliforniaAges 21–65 - NCT06762210Recruiting
Quit smoking with AI and dental health checks
This trial tests whether a smartphone app that uses artificial intelligence (AI) can help you quit smoking by looking at how it affects your dental health. If you smoke at least 5 cigarettes a day and want to quit, you may be able to join.
Fayoum, Alexandria GovernorateAges 21–65 - NCT06983678Recruiting
Quitting smoking and pain sensitivity study
This study looks at how quitting smoking affects pain sensitivity in people who smoke, especially those with chronic low back pain. Researchers will use brain scans and daily surveys to understand these changes.
Durham, North CarolinaAges 21–65 - NCT07198971Recruiting
Music therapy to help cancer patients quit smoking
This study tests whether adding music therapy sessions can help people with cancer quit smoking more easily. You'll work with a tobacco addiction nurse and a music therapist to see if the music part makes it easier to stick with quitting.
Montpellier, HeraultAges 18 years+ - NCT03495024RecruitingPhase 4
Varenicline for quitting smoking in people with schizophrenia
This trial tests whether varenicline helps people with schizophrenia or schizoaffective disorder stop smoking. It also looks at related nervous-system side effects that can happen with some anti-psychotic medicines.
Philadelphia, PennsylvaniaAges 18–75 - NCT07001930RecruitingPhase 1
Cannabidiol effects on stress and nicotine withdrawal
This trial tests whether a cannabis-derived compound called cannabidiol (CBD) can help people who smoke cigarettes cope with stress and withdrawal symptoms when they stop smoking. CBD is not the part of cannabis that makes you high.
Baltimore, MarylandAges 21–70 - NCT06444971Recruiting
Muscle relaxation for better lung function in smokers
This study tests a simple muscle relaxation technique to see if it improves how well your lungs work and how easily you breathe. If you are a smoker, this may help you understand more about your lung health.
Rawalpindi, Punjab ProvinceAges 18–60 - NCT06630728RecruitingPhase 4
How Addictive Are Very Low Nicotine Little Cigars?
This study is testing whether little cigars with very low nicotine are less addictive than regular ones. Researchers want to see how smoking these affects your mood, cravings, and smoking behavior.
Columbus, OhioAges 21–75 - NCT07027956Recruiting
Smoking and lung function study
This study measures how well your lungs work and how much oxygen is in your blood. It compares smokers and non-smokers to see if smoking affects breathing.
KırşehirAges 18–65 - NCT07598136Recruiting
How e-cigarette flavors affect smoking habits
This study looks at whether different flavors in e-cigarettes help smokers quit or reduce regular cigarettes. You'll use e-cigarettes with different flavors while researchers track your smoking habits through a smartphone app.
Maitland, FloridaAges 21–65 - NCT07419425RecruitingPhase 4
Help for Black adults to quit smoking
This study tests a program to help Black adults who smoke quit. It offers support and medication to help you stop smoking.
Phoenix, ArizonaAges 21 years+ - NCT04715568RecruitingPhase 4
Testing how smoke exposure affects heart health
This study looks at whether being exposed to secondhand tobacco smoke at work affects heart and blood vessel health. It may help researchers understand which people are at higher risk and how the body responds to that exposure.
San Francisco, CaliforniaAges 40 years+ - NCT04722835Recruiting
Study lung immune cells in people at risk for COPD
This study looks at different lung immune cell patterns and how they work in smokers who are not yet diagnosed with COPD or asthma. It may help researchers understand why some people are more likely to develop COPD, which could guide future prevention or early treatments.
San Francisco, CaliforniaAges 40–75 - NCT05992272Recruiting
How cues affect drinking and smoking habits
This study looks at how certain cues (like seeing a drink or a cigarette) trigger cravings and behavior in people who drink alcohol or smoke. Understanding this may help improve addiction treatments.
BerlinAges 16–65 - NCT06673225Recruiting
INSPIRE respiratory health program in Botucatu
This study tests a respiratory health program for adults with breathing symptoms and a history of smoking. It aims to see if the program improves lung health and quality of life.
Botucatu, São PauloAges 18 years+ - NCT06922617Recruiting
E-cigarettes vs. Nicotine Replacement for Smoking in Substance Use Treatment
This study compares e-cigarettes to nicotine replacement therapy (like patches or gum) to help people who are in treatment for substance use disorder (like drugs or alcohol) quit or reduce smoking. It aims to find a safer way to cut back on cigarettes.
Charleston, South CarolinaAges 21 years+ - NCT07039175RecruitingPhase 3
Helping veterans with chronic disease change smoking or drinking habits
This study tests a program to help veterans with diabetes, heart disease, or related conditions who are thinking about cutting back on smoking or alcohol. The goal is to see if the program can motivate positive changes in these habits.
Buffalo, New YorkAges 18 years+
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Common questions
- Are there clinical trials for tobacco smoking?
- Yes. Clin2 currently lists 125 recruiting tobacco smoking studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tobacco smoking trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tobacco smoking trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.