Clinical trials
Tolerance clinical trials
Below are recruiting tolerance clinical trials, each written for real people, not researchers. We’re tracking 946 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07125183RecruitingPhase 2
Weekly chemo for advanced leiomyosarcoma in older adults
This trial tests whether weekly doxorubicin is effective and tolerable for people aged 65 and older with advanced or metastatic leiomyosarcoma. It may be a good option if you have not had this type of chemo before.
Aurora, ColoradoAges 65–100 - NCT07126873RecruitingPhase 1/Phase 2
Study of E-islet 01 for type 1 diabetes with severe low blood sugar
This study tests a new treatment called E-islet 01, which may help people with type 1 diabetes who have very low natural insulin production and have had dangerous low blood sugar events. The goal is to see if it is safe and can reduce those episodes.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07128797RecruitingPhase 1
Safety and tolerability of B1344 injections for NAFLD
This trial tests whether multiple injections of B1344 are safe and tolerable in people with nonalcoholic fatty liver disease (NAFLD). It aims to find the right dose and check how the drug works in the body.
Beijing, Beijing MunicipalityAges 18–75 - NCT07138144RecruitingPhase 4
Switching to a two-drug HIV pill vs. staying on three drugs
This study tests whether switching to a simpler, two-drug HIV pill (dolutegravir/lamivudine) is as safe and effective as staying on a three-drug regimen. It is for people whose HIV is already well-controlled and who are currently taking Biktarvy or Triumeq.
Mexico City, Mexico CityAges 18–70 - NCT07140900RecruitingPhase 1
Study of xaluritamig combined with hormone therapy for advanced prostate cancer
This trial tests a new drug, xaluritamig, given with standard hormone therapy for men with prostate cancer that has spread to other parts of the body (metastatic) and is still sensitive to hormone therapy. It aims to see if the combination is safe and works better than hormone therapy alone.
San Francisco, CaliforniaAges 18 years+ - NCT07142707RecruitingPhase 1
Testing a new obesity drug for safety and effects
This study tests an investigational medication called MBX 4291 for adults with obesity. It aims to see if the drug is safe and how it works in the body, which could lead to a new weight-loss treatment option.
Doral, FloridaAges 18–65 - NCT07143539Recruiting
Early exercise rehab after hospital stay for pulmonary embolism
This study tests if starting a supervised exercise program early after a hospital stay for a blood clot in the lungs (pulmonary embolism) helps patients recover better and feel less breathless. It is for people at higher risk of ongoing symptoms after their clot.
AarauAges 18 years+ - NCT07148128RecruitingPhase 1/Phase 2
Testing the safety of WEF-001 for KRAS-mutant cancers
This trial studies a new drug called WEF-001 for people with advanced cancers that have a KRAS mutation. It aims to see if the drug is safe and shrinks tumors when used alone.
Dallas, TexasAges 18 years+ - NCT07149831RecruitingPhase 1
Safety study of a diagnostic injection in healthy Chinese adults
This trial tests a new imaging agent called flotufolastat F-18 in healthy volunteers to see how it travels through the body and how safe it is. The results will help doctors use this agent for imaging in future patients.
Beijing, Beijing MunicipalityAges 18–60 - NCT07155252Recruiting
Home glucose test for type 1 diabetes screening
This study looks at whether you can do an oral glucose tolerance test at home instead of at a clinic. It is for people who have certain antibodies linked to type 1 diabetes or who were recently diagnosed with type 1 diabetes.
New Haven, ConnecticutAges 8–45 - NCT07166081RecruitingPhase 1
Study of BGM0504 tablets in overweight or obese adults
This study tests an investigational tablet called BGM0504 for weight management in adults with overweight or obesity but without diabetes. It looks at how the drug works in your body and how safe it is over time.
Baltimore, MarylandAges 18–65 - NCT07169318RecruitingPhase 1
Safety study of VNT-101 in healthy adults
This first-in-human study tests the safety of a new medicine called VNT-101. Healthy adults aged 18 to 59 who do not smoke and have no major health problems may be able to join. The goal is to see how the body handles the drug and if it is safe.
Overland Park, KansasAges 18–59 - NCT07169591Recruiting
How birth control affects blood sugar after meals
This study looks at how your body handles blood sugar after a meal if you use a specific type of birth control (certain birth control pills or IUDs) or no hormonal birth control. It may help researchers understand how hormones affect energy and sugar levels.
Hamilton, OntarioAges 18–45 - NCT07171983RecruitingPhase 1
Testing a new drug for rheumatoid arthritis
This trial tests a new medication (BMS-986454) for people with rheumatoid arthritis who haven't responded well enough to methotrexate. It aims to see if the drug is safe and how it works in the body.
Hyderabad, Andhra PradeshAges 18–65 - NCT07182656RecruitingPhase 1
Safety of CIGB-814 in healthy Chinese volunteers
This is a first-in-human study in China testing a new drug called CIGB-814 in healthy volunteers. The goal is to check how safe the drug is, how well it is tolerated, and how the body processes it.
Beijing, Beijing MunicipalityAges 18–45 - NCT07185256RecruitingPhase 1/Phase 2
Gene therapy for Best disease retinal trial
This trial tests a gene therapy called OPGx-BEST1 injected under the retina to treat vision loss from Best vitelliform macular dystrophy or a related condition. It may help people with advanced disease who have a specific genetic change in the BEST1 gene.
Los Angeles, CaliforniaAges 18 years+ - NCT07185815RecruitingPhase 1/Phase 2
Study of a long-acting cariprazine shot for mood and schizophrenia
This trial tests a monthly injection of cariprazine (a medication for mental health conditions) in people who could benefit from it. It aims to see if the shot is safe, tolerable, and effective compared to taking pills every day.
AhmedabadAges 18–64 - NCT07185880RecruitingPhase 1/Phase 2
Testing MT-125 for newly diagnosed glioblastoma
This trial tests a new drug called MT-125 for people with a specific type of brain cancer called glioblastoma (GBM) that is IDH wildtype and MGMT unmethylated. The study will see if MT-125 is safe and tolerable, and how well it works.
Phoenix, ArizonaAges 18 years+ - NCT07190209RecruitingPhase 3
Testing lunsekimig for COPD with frequent flare-ups
This trial tests a new medicine called lunsekimig for people with COPD that still causes flare-ups despite standard treatment. It focuses on people with higher blood eosinophils (a type of white blood cell). If you smoke or used to smoke and have had at least 2 moderate or 1 severe flare-up in the past year, this study may be an option.
Chandler, ArizonaAges 40–80 - NCT07190222RecruitingPhase 3
New medicine for COPD with frequent flare-ups
This study tests a new medicine called Lunsekimig for people with COPD that has frequent flare-ups and high eosinophil levels (a sign of inflammation). It aims to see if it can help control symptoms better than a placebo (a dummy treatment).
Birmingham, AlabamaAges 40–80 - NCT07197814Recruiting
Tolerance of a rice protein formula in children with cow's milk allergy
This study tests a new formula made from rice protein in children who have a cow's milk allergy. It checks if the rice formula is well-tolerated without causing allergic reactions.
NaplesAges 1 month–3 years - NCT07198100Recruiting
Ear stimulation, motivation, and insulin sensitivity in depression
This study explores how a gentle electrical stimulation of the ear might affect mood, motivation, and insulin sensitivity in people with and without depression. It aims to see if this non-invasive technique could offer new ways to help with depression.
BonnAges 18–60 - NCT07198555RecruitingPhase 1
Study of BBM-A101 for knee osteoarthritis
This trial tests a new medicine called BBM-A101 for people with moderate knee osteoarthritis. It aims to see if it is safe and helps reduce pain and improve function.
Shenzhen, GuangdongAges 40–75 - NCT07210658Recruiting
Nutritional supplement tolerance study in children
This study is testing a new nutritional drink or powder to see if children like it, tolerate it well, and can stick with it. It replaces your child's current supplement with a new one, and researchers will check how it affects their digestion and overall health.
NottinghamAges 1–16
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Common questions
- Are there clinical trials for tolerance?
- Yes. Clin2 currently lists 946 recruiting tolerance studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tolerance trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tolerance trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.