Clinical trials
Tonsillitis clinical trials
Below are recruiting tonsillitis clinical trials, each written for real people, not researchers. We’re tracking 20 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05459935Recruiting
Light treatment for enlarged tonsils in children
This trial studies whether a light-based treatment (called photobiomodulation) can help children with very enlarged tonsils. It may improve breathing and sleep symptoms, and you’d have before-and-after checkups, including sleep testing.
Edmonton, AlbertaAges 6–12 - NCT05575401Recruiting
Track surgery results in kids getting tonsil removal
This trial looks at how well a specific throat surgery technique works in children who are having their tonsils removed (with or without removing adenoids). It may help improve how doctors choose and perform surgery for safer, better recovery.
Murrieta, CaliforniaAges 3–17 - NCT05656365Recruiting
Study of genes and immunity in PFAPA and other tonsil problems
This study looks at genetic markers and immune system patterns in people with PFAPA (periodic fevers with mouth sores and throat/neck gland symptoms) or similar tonsil problems. It may help researchers understand why these conditions happen and how they might be better diagnosed or treated.
Washington D.C., District of ColumbiaAges 1 month–99 years - NCT06606262Recruiting
Tonsil removal surgery: total vs partial for recurrent tonsillitis
This study compares two different surgeries for treating frequent tonsillitis (sore throats that come back often): removing the entire tonsils versus removing only part of them. It aims to see which approach works better and has fewer side effects.
AalborgAges 15 years+ - NCT06543823Recruiting
New bandage for throat surgery pain relief
This trial tests a special wound dressing (SUPRATHEL 250) placed inside the throat after tonsil removal. It aims to see if it helps throat wounds heal faster with less pain.
Stuttgart, Baden-WurttembergAges 18 years+ - NCT03829033Recruiting
Photon vs proton radiation for early tonsil cancer
This trial compares two types of radiation—photon therapy and proton therapy—for early-stage tonsil cancer. The goal is to see which approach works well for cure while affecting surrounding tissues differently.
GävleAges 18 years+ - NCT07035314Recruiting
Comparing medicines for pain after tonsil removal in children
This study compares two ways to manage pain after tonsil removal in children: a medication given by mouth or injection versus a medication applied directly to the surgical site. The goal is to find which approach works better for pain control.
CairoAges 4–10 - NCT06915038Recruiting
Measuring tumor DNA in blood for HPV-positive throat cancer
This study looks at a blood test that finds DNA from HPV-related throat tumors. It may help doctors decide on surgery and check if the cancer is completely removed.
Carmel, IndianaAges 18 years+ - NCT07569939Recruiting
Treatment options for sore throat from viral infection
This study tests different treatments to help ease sore throat pain and symptoms caused by viral throat infections. It aims to find the best way to relieve discomfort when you have pharyngitis, tonsillitis, or a viral sore throat that started recently.
Clermont-FerrandAges 18–70 - NCT03556228RecruitingPhase 1/Phase 2
Tested medicine for tumors with TrkA changes, alone or with pembrolizumab
This early-phase study tests VMD-928, a targeted cancer medicine, for cancers that have TrkA-related tumor changes. It may be given by itself or with pembrolizumab to see if it can shrink tumors when standard treatments have not worked.
Santa Rosa, CaliforniaAges 18–80 - NCT03625011RecruitingPhase 4
Gabapentin before tonsil surgery to reduce pain
This trial tests whether giving gabapentin before pediatric tonsil (and possibly adenoid) removal can reduce postoperative pain. It may help children feel more comfortable after surgery while still being safe to use in the right patients.
Atlanta, GeorgiaAges 3–18 - NCT04083417RecruitingPhase 4
Sore throat study comparing antibiotics versus no antibiotics
This trial looks at whether phenoxymethylpenicillin (an antibiotic) helps people with a certain type of sore throat more than not using antibiotics. You may qualify if your symptoms match a likely bacterial cause and a rapid test for strep is negative.
JönköpingAges 15 years+ - NCT04277858RecruitingPhase 2
Pre-surgery chemo plus robotic surgery for p16-positive throat cancer
This trial tests whether giving chemotherapy before robotic surgery works well for certain p16-positive oropharyngeal (throat) cancers. It aims to shrink or control the cancer and allow the surgeon to remove the tumor with clean margins while avoiding cancer spread beyond the neck.
Montreal, QuebecAges 18–80 - NCT06258837Recruiting
Personalized surgery for sleep apnea in children with small tonsils
This study tests a personalized surgical approach for children with moderate to severe obstructive sleep apnea who have small tonsils. The goal is to see if tailored surgery improves their breathing during sleep and overall health.
Ann Arbor, MichiganAges 2–17 - NCT06576830RecruitingPhase 4
Pain relief study for kids having tonsil surgery
This study tests different ways to manage pain after tonsillectomy in children. The goal is to find better pain relief options.
Durham, North CarolinaAges 3–17 - NCT06851988Recruiting
Can exercise boost immunity and reduce head and neck cancer relapse?
This study tests whether a supervised exercise program can boost your immune system and lower the chances of cancer coming back after chemoradiation for head and neck cancer.
New Taipei CityAges 20–80 - NCT06902623Recruiting
Less intense radiation for early HPV throat cancer
This study tries to see if less intense radiation can still work well for certain throat cancers linked to HPV. It is looking for people with early stage HPV-positive oropharynx cancer who may benefit from a lighter treatment plan.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07093749Recruiting
Antibiotics and symptom tracking in children
This study looks at how children with common infections feel while taking antibiotics. The goal is to better understand symptom patterns during treatment.
Melbourne, VictoriaAges 4–17 - NCT07332780Recruiting
Tonsil and adenoid surgery for kids with mild breathing troubles during sleep
This study looks at whether removing tonsils and adenoids can help improve spine curves in children who have mild sleep-disordered breathing. It may help prevent scoliosis from getting worse.
Wenzhou, ZhejiangAges 6–15 - NCT07577232Recruiting
Ultrasound imaging for diagnosing throat abscesses
This trial tests whether using ultrasound (sound wave imaging) through the mouth helps doctors better diagnose a throat abscess—a pocket of infection near the tonsil. The goal is to see if this imaging method improves diagnosis accuracy and treatment decisions.
CopenhagenAges 18 years+
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Common questions
- Are there clinical trials for tonsillitis?
- Yes. Clin2 currently lists 20 recruiting tonsillitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tonsillitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tonsillitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.