Clinical trials
Toxicity clinical trials
Below are recruiting toxicity clinical trials, each written for real people, not researchers. We’re tracking 216 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05301101Recruiting
Re-irradiation planning for tumors near previously treated organs
This study tests a more personalized way to plan “re-irradiation,” meaning giving radiation again in an area that was already treated before. It aims to better calculate organ risk to reduce harmful side effects while treating cancer.
Milwaukee, WisconsinAges 18 years+ - NCT06657846Recruiting
Quality of life and costs for people with VEXAS
This study looks at how VEXAS syndrome affects your daily life and finances. It aims to understand the challenges you face so doctors can better support you.
AnconaAges 18–99 - NCT05832606Recruiting
Food changes to reduce side effects from immunotherapy
This trial tests whether a specific food plan can reduce side effects (toxicity) from standard immunotherapy that targets PD-1 and/or CTLA-4. It may help people tolerate treatment better while staying on their usual cancer care.
JetteAges 18 years+ - NCT04871542Recruiting
Predicting risk of immune therapy side effects
This study tries to predict who is more likely to get serious side effects from immune checkpoint medicines used for solid tumors. You may help researchers by answering questionnaires before treatment and during follow-up, and by possibly storing sample specimens.
Anchorage, AlaskaAges 18 years+ - NCT07473271Enrolling by invitation
Vaginal therapy devices after pelvic radiation
This trial tests special exerciser and irrigation devices to help with vaginal recovery after pelvic radiation. It may help reduce side effects like narrowing or dryness.
Beijing, Beijing MunicipalityAges 18–70 - NCT07485608Recruiting
Reducing lead dust in older homes
This study tests whether cleaning and other methods can lower lead dust in homes built before 1978. It may help protect your child from lead exposure.
East Lansing, MichiganAges Up to 7 years - NCT07456592Recruiting
A test to detect toxic herbs in urine for aconite poisoning
This trial is testing a new device that can quickly detect poisonous Chinese herbs, like aconite, in a person's urine. It may help doctors diagnose poisoning faster and more easily.
Hong KongAges 18 years+ - NCT07388407Recruiting
Genetics of leflunomide for rheumatoid arthritis
This study looks at how your genes might affect how well leflunomide works for rheumatoid arthritis. It is for Pakistani adults who are starting or recently started leflunomide, and will help doctors understand who might respond best.
Islamabad, Punjab ProvinceAges 20–65 - NCT07227792Recruiting
Tongue-out radiation therapy for head and neck cancer
This trial tests if sticking your tongue out during radiation therapy can reduce side effects. It is for people with certain types of head and neck cancer who are getting radiation to the main tumor.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT03417336Recruiting
Radiation for prostate cancer using smaller, targeted doses
This trial studies a specific radiation schedule for prostate cancer (with an extra “boost” dose) and checks whether it works well and is tolerable. It may help people with higher-risk, localized prostate cancer by aiming at the cancer while limiting side effects to surrounding tissues.
DijonAges 18–85 - NCT06826534Recruiting
At-home heart rehab for teens with heart failure risk
This study tests if a home-based exercise program using a Fitbit can help teens who had chemotherapy improve their heart and lung fitness. You would exercise at home, track your activity, and have monthly virtual check-ins for 6 months.
Los Angeles, CaliforniaAges birth–21 years - NCT07217262Recruiting
Proactive Costs of Care Study
This study looks at the costs and challenges of cancer care for people with gynecologic cancers and their caregivers. By joining, you'll help researchers understand how to better support patients and families during treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT06830863RecruitingPhase 1/Phase 2
Cream for EGFR inhibitor skin rash
This trial tests a new cream called ATR04-484 to see if it can help with the painful rash that often appears on the face and chest during EGFR inhibitor cancer treatment. The cream is applied to the skin, with the goal of reducing redness, bumps, and discomfort.
Hot Springs, ArkansasAges 18 years+ - NCT03514368Recruiting
Testing immune markers to track cancer treatment safety and benefit
This study collects blood and tumor samples to understand how well cancer immunotherapy works and what side effects may happen. It mainly helps researchers by checking “immune markers” before treatment starts, while you receive planned immune checkpoint therapy.
ToulouseAges 18 years+ - NCT06863324Recruiting
Impact of radiation sensitivity on late side effects of facial pain radiosurgery
This study looks at whether how sensitive people are to radiation affects late side effects after radiosurgery for trigeminal neuralgia. It may help doctors better predict and prevent long-term problems.
Nice, Alpes-maritimesAges 18 years+ - NCT07018622RecruitingPhase 2
Protecting kidneys from platinum chemotherapy damage
This trial tests a way to protect your kidneys while you receive platinum-based chemotherapy (cisplatin or carboplatin) for a solid tumor. It may help reduce the risk of kidney damage so you can complete your treatment more safely.
México, TlalpanAges 18 years+ - NCT05978024Recruiting
Predicting how sarcoma responds and side effects from limb radiotherapy
This study collects information to predict how soft tissue sarcoma in an arm or leg will respond to radiotherapy and what side effects may happen. It may help doctors improve planning and follow-up for people like you.
CambridgeAges 16 years+ - NCT06709404Recruiting
Telehealth support for caregivers of HIPEC patients
This study tests a telehealth program to help caregivers manage distress and financial stress while caring for someone receiving a special surgery (CS+HIPEC). It aims to see if the program improves caregivers' well-being.
Winston-Salem, North CarolinaAges 18 years+ - NCT06679387RecruitingPhase 2
Memantine to prevent paclitaxel nerve damage in breast cancer
This trial tests whether the drug memantine can help prevent or reduce nerve pain and other side effects caused by the chemotherapy drug paclitaxel in breast cancer patients. If you are about to start weekly paclitaxel, this study may offer extra protection to your nerves.
CairoAges 18 years+ - NCT06382649RecruitingPhase 2
Rivastigmine for drug-induced confusion
This study tests whether the drug rivastigmine can help people who are very agitated and confused due to certain drug side effects. If it works, it could calm them down and improve their confusion.
St Louis, MissouriAges 10 years+ - NCT07064330Recruiting
Blood test for immune markers in skin cancer patients on cemiplimab
This trial is testing whether a new blood test can predict how well the drug cemiplimab works for skin cancer and if it causes side effects. It may help doctors better match treatments to patients.
Salamanca, SalamancaAges 18 years+ - NCT07167225Recruiting
E-cigarette and cannabis co-use in young adults
This study looks at how using e-cigarettes and cannabis together affects exposure to harmful chemicals in young adults aged 18-25. It aims to understand the risks of co-use to help guide healthier choices.
Buffalo, New YorkAges 18–25 - NCT07381634RecruitingPhase 2
Testing ondansetron to reduce immunotherapy side effects in liver cancer
This study tests whether adding ondansetron (a common anti-nausea drug) can reduce side effects from immunotherapy in people with liver cancer. If you are starting a specific combination treatment for liver cancer, you may be eligible.
Wenzhou, ZhejiangAges 18–80 - NCT06627595Recruiting
Exercise and immunotherapy side effects in melanoma
This study looks at whether physical activity can help reduce side effects from immunotherapy in people with melanoma. You may join if you are starting a certain type of immunotherapy for melanoma.
MontpellierAges 18 years+
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Common questions
- Are there clinical trials for toxicity?
- Yes. Clin2 currently lists 216 recruiting toxicity studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a toxicity trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a toxicity trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.