Clinical trials
Trust clinical trials
Below are recruiting trust clinical trials, each written for real people, not researchers. We’re tracking 471 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05118555Recruiting
Tests new MRI scan methods during routine scans
This study checks whether new MRI scan techniques work and add useful information. It may help your care by improving MRI methods, but you would need extra scan time/data for the test.
Sutton, SurreyAges 18 years+ - NCT05123443Recruiting
Study tracks iron changes in MS brain spots over time
This study looks at how “iron rims” in brain MRI scans change over time in people with multiple sclerosis (MS). It may help researchers understand MS activity better and how iron changes relate to disease progression.
NottinghamAges 16 years+ - NCT05189600Recruiting
Testing breathing wave signals to improve airway treatment
This trial studies whether special breathing recordings taken during assisted air “insufflation–exsufflation” can show how your larynx (voice box) responds. The goal is to use those signals to fine-tune the best treatment settings for people with neuromuscular conditions.
LondonAges 18 years+ - NCT05191680RecruitingPhase 2
Testing apalutamide in early prostate cancer active surveillance
This Phase 2 trial tests whether apalutamide can help people with early prostate cancer who choose active surveillance. It uses MRI and biopsy results to confirm the cancer type and location, then checks if treatment is safe and potentially helpful.
Cambridge, CambridgeshireAges 18 years+ - NCT05219058Recruiting
Rebuilding after major pelvic cancer surgery
This study looks at reconstruction (how tissue is rebuilt) after very large pelvic cancer surgeries. It may help teams improve the options and support for people having these operations and recovery experiences.
Southampton, HampshireAges 18 years+ - NCT05224193Recruiting
Study of exercise and sleep in kids with inflammatory bowel disease
This study looks at how physical activity and sleep habits affect children and teens with inflammatory bowel disease. It may help doctors understand which routines could support better day-to-day health and disease management.
Southampton, HampshireAges 6–18 - NCT05231655Recruiting
Study testing fresh tumor tissue from cancer surgery or biopsy
This study collects fresh samples of tumor tissue during procedures like surgery, biopsy, or TURBT to test a cancer therapy outside the body. It may help researchers learn which treatments work better for different solid cancers.
Sheffield, South YorkshireAges 16 years+ - NCT05298436Recruiting
South London stroke registry using health data
This study collects information about people who have had a stroke to learn how to improve care and support. It mainly uses existing medical and health records rather than testing a new medicine.
LondonAges 18 years+ - NCT05331066Recruiting
Tracking side effects from immunotherapy using multiple tests
This study looks at how side effects happen in people receiving immune checkpoint inhibitor immunotherapy for solid cancers. It uses multiple types of tests to better understand these toxicities and may help improve safety and care in the future.
Chelsea, LondonAges 18 years+ - NCT05344209RecruitingPhase 2
Pembrolizumab plus or minus vaccine for advanced lung cancer
This Phase 2 trial studies pembrolizumab (an immune-boosting cancer medicine) alone or with an added investigational UV1 vaccine in people with advanced non-small cell lung cancer. It aims to see whether adding the vaccine improves safety and effectiveness, especially in tumors with high PD-L1 levels.
Drammen, AkershusAges 18 years+ - NCT05364788Recruiting
Study of tumor tissue in appendiceal cancer after surgery
This study looks at stored tumor samples to better understand appendiceal cancer that has spread to the lining of the abdomen (peritoneal metastases). Your tumor tissue from past procedures may help researchers learn more about the cancer and how it behaves.
ManchesterAges 18 years+ - NCT05375591Recruiting
AI study to sort lung nodules after past cancer treatment
This study uses computer tools (AI) and detailed scan patterns to better classify new lung nodules in people who previously had curative-intent cancer treatment. It may help doctors decide whether a nodule is likely benign or cancer, using your CT scan and related medical history.
LondonAges 18 years+ - NCT05389410Recruiting
PICO dressings compared during repeat hip or knee surgery
This study compares two types of wound dressings (PICO 7 vs PICO 14) in people having a repeat (revision) hip or knee operation. It aims to see which dressing works better to help the surgical wound heal after surgery.
Oswestry, ShropshireAges 18 years+ - NCT05389774Recruiting
Testing an AI tool that predicts lung cancer risk from CT scans
This study tests whether Optellum’s AI prediction tool can better identify which lung nodules found on CT scans are more likely to be cancer. You may be asked to provide specific types of CT images so the tool can be evaluated.
BangorAges 35 years+ - NCT05392894RecruitingPhase 3
Transplant using a half-matched donor for severe sickle cell
This trial tests whether a half-matched (haploidentical) blood stem cell transplant can treat adults with severe sickle cell disease. It may help reduce serious complications and improve survival, but it requires a fit health status and specific donor and medical conditions.
LondonAges 18 years+ - NCT05432739Recruiting
Test a lung nodule blood/scan marker to find early cancer
This study looks at whether a new test can better identify early lung cancer in people who are being watched for an incidental lung nodule. It may help doctors decide which nodules need closer follow-up or treatment.
Goodmayes, EssexAges 18 years+ - NCT05434104Recruiting
Trial tests vaginal lactoferrin instead of medicines for BV or thrush
This study checks whether using lactoferrin vaginal pessaries can work for bacterial vaginosis (BV) or thrush, compared with standard antibiotic or antifungal tablets. It’s a feasibility study, meaning the main goal is to see if the approach and home sample collection are practical.
LondonAges 16–50 - NCT05449691Recruiting
Compare natural tissue samples with synthetic mesh in breast reconstruction
This study looks at how “biological” materials compare with synthetic mesh during immediate, one-stage breast reconstruction after mastectomy. It may help doctors choose the best support material to improve reconstruction outcomes for women undergoing this surgery.
DerbyAges 18 years+ - NCT05450991Recruiting
Study outcomes in children with Hirschsprung’s disease
This study looks at long-term health and development outcomes in children who were diagnosed and treated for Hirschsprung’s disease or anorectal malformations. It uses both numbers and interviews to understand what happens over time after treatment, helping families and clinicians plan better care.
Liverpool, MerseysideAges Any age - NCT05457725Recruiting
Study how aging affects learning to trust and distrust
This study looks at how thinking and learning processes change with age, especially around deciding what to trust. You may be asked to complete computer tasks and brief memory/thinking tests to understand these changes.
Gainesville, FloridaAges 18–100 - NCT05521451Recruiting
Study for adults with heart rhythm problems
This trial is a “clinical cohort” study, meaning it follows adults with certain heart rhythm issues to understand them better. Your participation may help researchers learn what to expect and how best to support people over time.
HamburgAges 18 years+ - NCT05553899Recruiting
PET-MRI scans for monitoring children’s brain tumor return
This study checks whether a special scan called PET-MRI can better tell if a child’s brain tumor has come back after treatment. It may help doctors decide faster and more accurately when changes seen on regular MRI are true tumor recurrence.
Sheffield, South YorkshireAges 8–18 - NCT05568069Recruiting
Study of defibrillator implants for non-ischemic weak heart
This study looks at whether implantable defibrillators can reduce dangerous heart rhythms in people with non-ischemic cardiomyopathy (heart weakness not caused by blocked heart arteries), a heart scar, and very low pumping strength despite best treatment. It compares different approaches to choosing which patients should receive these devices.
High Wycombe, BuckinghamshireAges 18 years+ - NCT05633303Recruiting
Personalized ablation plan for persistent atrial fibrillation
This trial looks at whether tailoring an ablation procedure to you can work better for people with persistent atrial fibrillation. It’s for patients getting their first left atrial ablation and who have had AF for less than 24 months.
LondonAges 18 years+
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Common questions
- Are there clinical trials for trust?
- Yes. Clin2 currently lists 471 recruiting trust studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a trust trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a trust trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.