Clinical trials
Tuberculosis clinical trials
Below are recruiting tuberculosis clinical trials, each written for real people, not researchers. We’re tracking 150 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04145258RecruitingPhase 3
Stronger TB treatment for meningitis to reduce deaths
This trial tests if giving a stronger combination of TB drugs for meningitis can save more lives. It's for patients who have been diagnosed with tuberculosis meningitis and have not yet started more than 5 days of TB treatment.
AbidjanAges 15 years+ - NCT04923958Recruiting
Testing new TB screening and diagnostic tests
This study tests rapid TB screening and lab-style diagnostic methods to see how well they find TB disease and TB that is resistant to rifampin (a key TB drug). It may help doctors diagnose TB faster and more accurately, especially in people at higher risk.
TbilisiAges 12 years+ - NCT04975178RecruitingPhase 3
Test of a TB vaccine for newborns in sub-Saharan Africa
This Phase 3 study tests whether MTBVAC can safely protect newborn babies from tuberculosis and whether it helps the baby’s immune system learn to fight TB. If you enroll, the goal is to see safety and immune response in real newborn settings in sub-Saharan Africa.
Worcester, Western CapeAges 5 minutes–1 week - NCT05317247Recruiting
Cough sound test to quickly triage possible tuberculosis
This trial checks whether listening to your cough on an audio recording can help triage—meaning sort—people who may have tuberculosis (TB). If you have had a cough for at least two weeks, the study may help doctors decide who needs further TB testing.
Cape Town, Western CapeAges 12 years+ - NCT05426720Recruiting
Looking for TB lung damage risk factors and blood markers
This study looks at what increases the risk of long-term lung damage after active pulmonary tuberculosis (TB). It also tests whether certain blood or other markers can predict who is more likely to have lung problems later.
BeijingAges 25–60 - NCT05588492RecruitingPhase 4
Rifamycin treatment to prevent TB after kidney transplant
This study looks at whether a rifamycin-containing medicine plan is safe and effective at preventing latent (hidden) TB after a kidney transplant. If your TB test shows you likely have hidden TB, you would be offered treatment to reduce the chance it becomes active TB.
TaipeiAges 20 years+ - NCT05590455RecruitingPhase 2
Testing a TNF-blocking drug to reduce death in HIV and TB meningitis
This Phase 2 trial studies whether a TNF-blocking medicine can lower the risk of death in people with HIV who also have TB meningitis. You would receive standard TB meningitis treatment plus the study drug, if you meet the criteria.
Rio de JaneiroAges 18 years+ - NCT05633056Recruiting
Testing TB medicines for people with drug-resistant TB and HIV
This trial studies a treatment plan for people who have both drug-resistant tuberculosis (TB) and HIV. It focuses on starting a specific TB medication (bedaquiline) and, if needed, HIV treatment soon after enrollment to see what approach works best.
Durban, KwaZulu-NatalAges 18 years+ - NCT05671718Recruiting
Nurse vs doctor treatment for drug-resistant tuberculosis
This trial compares a nurse-led plan versus a physician-led plan for treating new drug-resistant TB patients using an outpatient clinic approach. It may help by showing which care style works best and is safest for patients starting treatment close to home.
Pietermaritzburg, KwaZulu-NatalAges 18 years+ - NCT05842161Recruiting
Help quitting smoking for people with HIV and TB care
This study supports quitting smoking while you are receiving HIV and/or TB care. It aims to improve engagement in care and smoking cessation for people who smoke daily.
RondeboschAges 18 years+ - NCT05916638Recruiting
Testing a breathing pattern in people with sarcoidosis and TB
This trial looks at a specific “MoMa signature” related to breathing or lung signals in adults who have been diagnosed with both sarcoidosis and tuberculosis. It may help researchers understand how these conditions affect the body and improve how patients are monitored.
ParisAges 18 years+ - NCT05917210Recruiting
Peer support for TB and HIV treatment in Uganda
This trial tests a peer-led education and counseling program to help people with TB and HIV stick with their treatment. It may help improve understanding, motivation, and day-to-day adherence to medications.
KampalaAges 18 years+ - NCT05947890RecruitingPhase 2
Testing an immune-boosting TB vaccine in people with or without HIV
This Phase 2 study tests MTBVAC, a TB vaccine candidate, to see if it is safe and whether it helps the immune system. It may be a fit if you’re eligible for TB and HIV-related vaccine safety testing and can follow study visits and testing.
Johannesburg, GautengAges 12–55 - NCT05989802Recruiting
Testing new TB tests for children
This study is testing new ways to quickly diagnose TB in children under 15. It aims to find better tests that can be used at clinics, especially for kids who may not have obvious symptoms.
MaputoAges Up to 65 years - NCT06017843Recruiting
Using AI to find TB cases in community camps
This trial tests whether an AI tool can help find undiagnosed tuberculosis (TB) faster in community camps. If you are over 15 and visiting a camp site, you may be able to join and help improve TB detection.
IslamabadAges 15 years+ - NCT06057519RecruitingPhase 3
Optimized rifampicin dosing for TB
This trial tests whether higher or standard doses of the antibiotic rifampicin work better for treating pulmonary tuberculosis (a lung infection). You may benefit if you are starting TB treatment and have not had a bad reaction to rifampicin before.
TurinAges 18 years+ - NCT06114628RecruitingPhase 2
Finding the best treatment for lung TB (PARADIGM4TB)
This study tests different ways to treat active lung TB that is not resistant to rifampicin. It aims to find the best treatment duration and combination to cure TB and prevent it from coming back.
ChisinauAges 18 years+ - NCT06153069RecruitingPhase 4
Shorter tuberculosis treatment for people without symptoms
This trial tests a shorter treatment regimen for people with tuberculosis (TB) who don't have symptoms. If you have TB bacteria in your lungs but no cough, fever, night sweats, or weight loss, this study may offer a more convenient treatment option.
Beijing, Beijing MunicipalityAges 14–80 - NCT06272812RecruitingPhase 2
TB vaccine study for teens and adults
This trial tests whether a new vaccine called MTBVAC can prevent tuberculosis (TB) in people living in areas where TB is common. If you are between 14 and 45 years old and in good health, you may be able to join.
KisumuAges 14–45 - NCT06281834RecruitingPhase 1
Dolutegravir levels with TB prevention in children
This study tests how dolutegravir (an HIV medicine) works in children when taken with weekly rifapentine and isoniazid (medicines to prevent tuberculosis). It may help find the right dose for kids who have HIV and are at risk for TB.
Ibadan, Oyo StateAges 4 weeks–11 years - NCT06318416RecruitingPhase 1
Precision Rifampin Dosing for TB
This study tests whether giving a personalized dose of rifampin (a key TB medicine) can improve treatment. It is for people with active TB that is sensitive to rifampin, and it involves frequent blood and urine tests to measure drug levels.
HaydomAges 3 years+ - NCT06338215Recruiting
Moderate drinking vs. abstention advice for adults
This study compares two approaches for adults who drink regularly: advice on drinking in moderation vs. advice to stop drinking entirely. The goal is to see which approach better prevents major diseases and early death over time.
Pamplona, NavarreAges 50–75 - NCT06347939Recruiting
Lung lymph node biopsy study
This study tests a new way to take tissue samples from swollen lymph nodes in the chest using a thin tube passed through the mouth. It aims to see if this method is safe and effective.
LundAges 18 years+ - NCT06484530RecruitingPhase 4
Gene-guided NAC to prevent TB drug liver injury
This trial tests whether a medicine called N-acetylcysteine (NAC) can help prevent liver damage caused by standard TB drugs. If you have a higher risk of liver injury based on your genes, you may be given NAC along with your TB treatment.
Bangkok Noi, BangkokAges 18–80
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Common questions
- Are there clinical trials for tuberculosis?
- Yes. Clin2 currently lists 150 recruiting tuberculosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tuberculosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tuberculosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.