Clinical trials
Tuberculosis clinical trials
Below are recruiting tuberculosis clinical trials, each written for real people, not researchers. We’re tracking 147 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06526221Enrolling by invitation
Urine test to check TB medication use
This study checks a simple urine test to see if people with TB are taking their medication (isoniazid) regularly. It aims to help doctors find out sooner if someone is missing doses, so they can offer extra support.
Chennai, Tamil NaduAges 18 years+ - NCT06437184Recruiting
Finding TB cases with cough, sputum, or weight loss
This study aims to find more cases of tuberculosis (TB) in people with symptoms like cough, phlegm, or weight loss. If you may have TB, this trial will help diagnose and treat you sooner.
GonderAges 15–120 - NCT06352970Recruiting
TB infection and placenta function study
This study looks at how tuberculosis (TB) infection might affect the placenta and its function during pregnancy. If you are pregnant and giving birth soon, researchers want to learn if TB changes how the placenta grows and works.
Addis AbabaAges 18 years+ - NCT06314386Enrolling by invitation
Improving TB prevention in Eastern Cape clinics
This study looks at how to improve TB prevention in rural and semi-urban clinics in South Africa. They will work with clinic staff and district leaders to find better ways to stop TB.
AddoAges birth+ - NCT06221488Recruiting
TB testing for health workers at risk
This study tests health workers for tuberculosis (TB) infection to better understand who is at risk. It may help find ways to protect health workers from TB.
Cape TownAges 18–100 - NCT06192160RecruitingPhase 2
New TB drug combinations for drug-sensitive lung TB
This trial tests new combinations of TB medicines for people with active lung TB that is sensitive to standard drugs. It aims to find safer, shorter treatments that work just as well or better than current options.
GaboroneAges 18 years+ - NCT05807399RecruitingPhase 2
Step2c trial for new, drug-susceptible lung TB
This Phase 2 study tests treatment for people with newly diagnosed, drug-susceptible pulmonary (lung) tuberculosis (TB). It aims to see whether the study treatment works well and is safe for curing TB.
LambarénéAges 18–65 - NCT06113861Recruiting
Better TB testing for kids in Bolivia
This trial tests new ways to diagnose tuberculosis (TB) in children with breathing problems. It aims to make TB detection faster and more accurate for kids who might have the infection.
Santa CruzAges 2 months–14 years - NCT05941052Recruiting
Testing new at-home TB checks in the clinic
This study tests new tools that can check for tuberculosis (TB) more quickly at or near where care happens. It includes people with cough or TB risk factors, and also the health workers who perform TB testing, to see how well the tests work and how easy they are to use.
AbujaAges 12 years+ - NCT05553236Recruiting
Using gene testing to guide treatment for drug-resistant tuberculosis
This study uses next-generation gene testing to help manage active drug-resistant tuberculosis. It may help doctors choose the most appropriate treatment by better identifying the TB’s drug resistance.
Cape TownAges Any age - NCT05571735Recruiting
COVID vaccine immune response study in people with tuberculosis
This study measures how strongly your immune system responds to COVID-19 vaccines. It includes people with newly diagnosed tuberculosis and a healthier comparison group, aiming to understand vaccine immune effects and safety.
Mae Ramat, Changwat TakAges 18 years+ - NCT05473520RecruitingPhase 3
Doxycycline add-on therapy for lung improvement in tuberculosis
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
Kota Kinabalu, SabahAges 21 years+ - NCT05022862Recruiting
Check how incentives and vDOT help latent TB treatment
This trial studies whether reminder-based “vDOT” and small economic incentives can help people complete treatment for latent (sleeping) tuberculosis. If you have latent TB and are starting a standard medicine plan, it may help you stay on track and finish safely.
Baltimore, MarylandAges 18 years+ - NCT04700579Recruiting
Study lung changes before and after treatment for active TB
This study looks at changes in the lungs and immune system before TB treatment and again after treatment. By sampling lung fluid and comparing it over time, researchers hope to learn signatures that reflect how TB responds to care.
Cape Town, Western CapeAges 18–60 - NCT04052022Recruiting
Study of TB flare-ups in people without HIV
This study looks at why some people with tuberculosis (TB) get worse or develop new inflammation after they initially start improving on treatment—called a “paradoxical reaction.” It collects blood and tissue samples to better understand these flare-ups and guide future care.
Bethesda, MarylandAges 18–99 - NCT02527486Recruiting
Airways registry study for people with COPD symptoms
This registry collects information from people with COPD (and sometimes overlapping asthma-COPD features) to better understand breathing problems and airways behavior. It may help researchers learn which patterns match different symptom types, without necessarily using a new drug.
Seongnam-si, Gyeonggi-doAges 20–90 - NCT05426720Recruiting
Looking for TB lung damage risk factors and blood markers
This study looks at what increases the risk of long-term lung damage after active pulmonary tuberculosis (TB). It also tests whether certain blood or other markers can predict who is more likely to have lung problems later.
BeijingAges 25–60 - NCT05588492RecruitingPhase 4
Rifamycin treatment to prevent TB after kidney transplant
This study looks at whether a rifamycin-containing medicine plan is safe and effective at preventing latent (hidden) TB after a kidney transplant. If your TB test shows you likely have hidden TB, you would be offered treatment to reduce the chance it becomes active TB.
TaipeiAges 20 years+ - NCT02454569Recruiting
Study for people living with HIV willing to join
This study follows people who have tested positive for HIV. It aims to better understand HIV over time, but you can only participate if you agree to join the study.
Battalapalli, Andhra PradeshAges Any age - NCT05381194RecruitingPhase 4
Tested medicines for drug-resistant lung tuberculosis
This trial studies a specific drug combination (BPaLM) for adults with drug-resistant pulmonary (lung) tuberculosis. If you qualify, the goal is to see whether this treatment is effective and safe for your type of infection.
Seoul, Songpa-guAges 19 years+ - NCT06522347Recruiting
A lung infection registry study in Austria
This study creates a registry of patients in Austria who have a lung infection caused by tuberculosis or similar bacteria. By joining, you help researchers learn more about these infections and how to better treat them.
ViennaAges 18 years+ - NCT07784894RecruitingPhase 1
Study of an experimental drug with a birth control pill in healthy women
This trial tests how the body handles an experimental drug when taken with a combined birth control pill. It may help future use of the drug in women who are past menopause.
MadridAges 18–64 - NCT07762014RecruitingPhase 2
A new vaccine for respiratory infections in adults 60 and older
This trial tests a new vaccine designed to help protect older adults from infections that can affect breathing. You might be able to join if you're in generally good health and meet the other requirements listed below.
AthensAges 60 years+ - NCT07672405RecruitingPhase 2
Sorfequiline-based treatment for new drug-sensitive TB
This study tests a new medicine called sorfequiline, given in a combination regimen, to treat adults with drug-sensitive TB. It aims to see if sorfequiline can work as well as or better than standard treatment and shorten the time to cure.
Wentworth, DurbanAges 18–65
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Common questions
- Are there clinical trials for tuberculosis?
- Yes. Clin2 currently lists 147 recruiting tuberculosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tuberculosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tuberculosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.