Clinical trials
Tuberculosis clinical trials
Below are recruiting tuberculosis clinical trials, each written for real people, not researchers. We’re tracking 147 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06905522RecruitingPhase 3
Tuberculosis treatment trial for new patients
This trial tests a combination of drugs for people with active tuberculosis who have not been treated before. It aims to find a better way to treat TB, even if the bacteria are resistant to some drugs.
BeijingAges 18–65 - NCT06811025Enrolling by invitationPhase 1/Phase 2
Contezolid for treating tuberculous meningitis
This trial tests a new antibiotic called contezolid for people with tuberculous meningitis, an infection of the brain lining. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges Any age - NCT06347939Recruiting
Lung lymph node biopsy study
This study tests a new way to take tissue samples from swollen lymph nodes in the chest using a thin tube passed through the mouth. It aims to see if this method is safe and effective.
LundAges 18 years+ - NCT06796647Recruiting
TB skin test for patients with rheumatologic conditions
This trial is testing a new type of skin test (called ESAT6/CFP10) to check for TB infection in people who have a rheumatologic disease and are about to start certain medications (b/tsDMARDs). The goal is to see if this skin test works well for these patients.
Hong Kong, Hong KongAges 18–65 - NCT06744179Enrolling by invitation
Post-TB Sequelae Study: How the body heals after TB
This study looks at how the body recovers from tuberculosis (TB). It compares people who have had TB to those who have not, to understand long-term health effects. Participants will be asked to come for follow-up visits in Dhaka.
Dhaka, Dhaka DivisionAges 6 months+ - NCT06568484RecruitingPhase 2/Phase 3
Preventing TB with bedaquiline in people exposed to TB
This study tests if bedaquiline can prevent tuberculosis (TB) in people who have been in close contact with someone with active TB, including people living with HIV. If you qualify, you would take the study medicine and be monitored to see if it prevents you from developing TB.
UlaanbaatarAges Any age - NCT06497465RecruitingPhase 3
Two-drug HIV treatment for people with TB
This trial tests a two-drug HIV treatment for people who are new to HIV therapy and also have tuberculosis. It compares the two-drug combination to the standard three-drug regimen, with the goal of making treatment simpler while still being effective.
Manaus, AmazonasAges 15–99 - NCT06498414RecruitingPhase 2/Phase 3
Shorter and safer treatment for latent TB
This trial tests a shorter, safer treatment for people with latent TB infection (TB germs in your body but not making you sick). The goal is to prevent you from getting sick with active TB later.
CotonouAges 5 years+ - NCT06318416RecruitingPhase 1
Precision Rifampin Dosing for TB
This study tests whether giving a personalized dose of rifampin (a key TB medicine) can improve treatment. It is for people with active TB that is sensitive to rifampin, and it involves frequent blood and urine tests to measure drug levels.
HaydomAges 3 years+ - NCT06281834RecruitingPhase 1
Dolutegravir levels with TB prevention in children
This study tests how dolutegravir (an HIV medicine) works in children when taken with weekly rifapentine and isoniazid (medicines to prevent tuberculosis). It may help find the right dose for kids who have HIV and are at risk for TB.
Ibadan, Oyo StateAges 4 weeks–11 years - NCT06262282Enrolling by invitation
Phage therapy for stubborn NTM infection in cystic fibrosis
This trial tests whether a special virus therapy (phage) can help clear stubborn NTM lung infections in people with cystic fibrosis who have been on antibiotics for over a year without success. Participants will continue their antibiotics while receiving the phages.
Birmingham, AlabamaAges 6 years+ - NCT06114628RecruitingPhase 2
Finding the best treatment for lung TB (PARADIGM4TB)
This study tests different ways to treat active lung TB that is not resistant to rifampicin. It aims to find the best treatment duration and combination to cure TB and prevent it from coming back.
ChisinauAges 18 years+ - NCT06153069RecruitingPhase 4
Shorter tuberculosis treatment for people without symptoms
This trial tests a shorter treatment regimen for people with tuberculosis (TB) who don't have symptoms. If you have TB bacteria in your lungs but no cough, fever, night sweats, or weight loss, this study may offer a more convenient treatment option.
Beijing, Beijing MunicipalityAges 14–80 - NCT05671718Recruiting
Nurse vs doctor treatment for drug-resistant tuberculosis
This trial compares a nurse-led plan versus a physician-led plan for treating new drug-resistant TB patients using an outpatient clinic approach. It may help by showing which care style works best and is safest for patients starting treatment close to home.
Pietermaritzburg, KwaZulu-NatalAges 18 years+ - NCT06057519RecruitingPhase 3
Optimized rifampicin dosing for TB
This trial tests whether higher or standard doses of the antibiotic rifampicin work better for treating pulmonary tuberculosis (a lung infection). You may benefit if you are starting TB treatment and have not had a bad reaction to rifampicin before.
TurinAges 18 years+ - NCT05947890RecruitingPhase 2
Testing an immune-boosting TB vaccine in people with or without HIV
This Phase 2 study tests MTBVAC, a TB vaccine candidate, to see if it is safe and whether it helps the immune system. It may be a fit if you’re eligible for TB and HIV-related vaccine safety testing and can follow study visits and testing.
Johannesburg, GautengAges 12–55 - NCT05917210Recruiting
Peer support for TB and HIV treatment in Uganda
This trial tests a peer-led education and counseling program to help people with TB and HIV stick with their treatment. It may help improve understanding, motivation, and day-to-day adherence to medications.
KampalaAges 18 years+ - NCT05916638Recruiting
Testing a breathing pattern in people with sarcoidosis and TB
This trial looks at a specific “MoMa signature” related to breathing or lung signals in adults who have been diagnosed with both sarcoidosis and tuberculosis. It may help researchers understand how these conditions affect the body and improve how patients are monitored.
ParisAges 18 years+ - NCT05842161Recruiting
Smoking cessation program for people with HIV and TB in South Africa
This study is testing a program to help people who are living with HIV and TB to stop smoking. It aims to see if quitting smoking improves their engagement with HIV and TB care.
RondeboschAges 18 years+ - NCT05633056Recruiting
Testing TB medicines for people with drug-resistant TB and HIV
This trial studies a treatment plan for people who have both drug-resistant tuberculosis (TB) and HIV. It focuses on starting a specific TB medication (bedaquiline) and, if needed, HIV treatment soon after enrollment to see what approach works best.
Durban, KwaZulu-NatalAges 18 years+ - NCT05590455RecruitingPhase 2
Testing a TNF-blocking drug to reduce death in HIV and TB meningitis
This Phase 2 trial studies whether a TNF-blocking medicine can lower the risk of death in people with HIV who also have TB meningitis. You would receive standard TB meningitis treatment plus the study drug, if you meet the criteria.
Rio de JaneiroAges 18 years+ - NCT05317247Recruiting
Cough sound test to quickly triage possible tuberculosis
This trial checks whether listening to your cough on an audio recording can help triage—meaning sort—people who may have tuberculosis (TB). If you have had a cough for at least two weeks, the study may help doctors decide who needs further TB testing.
Cape Town, Western CapeAges 12 years+ - NCT05069688RecruitingPhase 1
Testing dolutegravir dosing in HIV and TB children
This study looks at the right way to dose dolutegravir (an HIV medicine) in young children who also have active tuberculosis (TB). Doctors will measure how the medicine moves through the body, especially when standard vs higher-dose rifampicin is used.
Ibadan, Oyo StateAges 4 weeks–5 years - NCT05117788Recruiting
Quick test for diagnosing tuberculosis
This study tests a new rapid test for tuberculosis (TB). It aims to see if the test can accurately detect TB in people with symptoms, which may lead to faster diagnosis and treatment.
Nairobi, Nairobi CountyAges 18 years+
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Common questions
- Are there clinical trials for tuberculosis?
- Yes. Clin2 currently lists 147 recruiting tuberculosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a tuberculosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a tuberculosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.