Clinical trials
Type 2 diabetes clinical trials
A condition where the body can’t use insulin properly, raising blood sugar. We’re tracking 1,078 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06078683Recruiting
Ketone drink for exercise and heart health in type 2 diabetes
This study tests whether a special ketone drink can improve exercise ability and heart function in people with type 2 diabetes. Participants will have two treadmill exercise tests and heart MRI scans to see how the drink affects their performance and cardiac efficiency.
Columbus, OhioAges 18–80 - NCT06120881RecruitingEarly Phase 1
Finding the Right Metformin Dose for Teens with Type 2 Diabetes
This study looks at how to give the right dose of metformin to young people with type 2 diabetes. If you join, you will wear a continuous glucose monitor for 6 weeks to help researchers find the best dose for you.
Oakland, CaliforniaAges 10–21 - NCT06143566RecruitingPhase 1/Phase 2
Polypill to prevent heart failure in diabetes and kidney disease
This trial tests a 'polypill' (a combination of several medicines in one pill) to prevent heart failure in people with type 2 diabetes and kidney disease. It may help reduce your risk of developing heart muscle problems.
Dallas, TexasAges 18–100 - NCT06169033Recruiting
Can belly fat scans predict weight-loss surgery success?
This study looks at how fat around your belly and inside your abdomen, seen on a CT scan, can predict how well bariatric (weight-loss) surgery will work for people with type 2 diabetes.
BeijingAges 16–70 - NCT06211556Recruiting
Reducing liver fat in type 2 diabetes
This study tests whether reducing liver fat can improve health in people with type 2 diabetes. It looks at the effects of a specific medication combined with exercise, tailored for those who are not very active.
Copenhagen, Capital RegionAges 30–70 - NCT06236581Recruiting
Blood sugar stability program for type 2 diabetes
This trial tests a program called GEM that helps people with type 2 diabetes keep their blood sugar steady by making changes to what they eat and how active they are. It is designed to reduce health disparities and may be a good fit if you are not on insulin or certain diabetes medications.
Augusta, GeorgiaAges 18 years+ - NCT06251635Recruiting
Antipsychotics and brain insulin in women
This study looks at how a common antipsychotic medication (olanzapine) affects how the brain uses insulin in young women. It aims to understand weight gain and metabolic changes linked to these drugs.
Toronto, OntarioAges 18–35 - NCT06256419Recruiting
Gene testing and exenatide response in Chinese type 2 diabetes patients
This study looks at how certain genes affect the risk of type 2 diabetes and how well the drug exenatide (a GLP-1 receptor agonist) works in Chinese patients. It aims to see if your genetic makeup can predict how you will respond to treatment.
Xuzhou, ChinaAges 25–70 - NCT06277466Recruiting
Gene changes and diabetes risk study
This study looks at how certain gene changes affect blood sugar control in type 2 diabetes and also in people who have had pancreas surgery. It compares these groups with healthy volunteers to see how genes influence the risk of diabetes.
XuzhouAges 25–70 - NCT06278207Recruiting
Finerenone in real-world diabetes and kidney disease
This study looks at how the medication finerenone works in everyday medical practice for people with type 2 diabetes and certain stages of chronic kidney disease. It aims to see how safe and effective the treatment is outside of a clinical trial setting.
Multiple Locations, New JerseyAges 18 years+ - NCT06293417Recruiting
Study of Ezefeno in patients with high cholesterol and type 2 diabetes
This trial tests a medicine called Ezefeno to see if it helps lower cholesterol in people with type 2 diabetes who are already on statins. It may be an option if you have high triglycerides and other heart risk factors.
SeoulAges 19 years+ - NCT06322212RecruitingEarly Phase 1
Type 2 diabetes and brain blood barrier study
This study tests if a treatment can improve the blood-brain barrier in adults with type 2 diabetes. It uses MRI scans to see changes and may help protect brain function.
Los Angeles, CaliforniaAges 40–65 - NCT06329544Recruiting
Study of a high-fructose diet and gut health
This trial tests how a high-fructose diet affects your gut bacteria and overall metabolic health. It is for people who already know they don't absorb fructose well (fructose malabsorbers) and want to understand how this sugar impacts their body.
New York, New YorkAges 25–45 - NCT06335771Recruiting
Study on fat metabolism in obesity and diabetes
This study looks at how fat is processed in the body for people with different health conditions, including obesity and type 2 diabetes. It aims to find new ways to improve treatment by understanding these differences.
Columbia, MissouriAges 18–70 - NCT06338215Recruiting
Moderate drinking vs. abstention advice for adults
This study compares two approaches for adults who drink regularly: advice on drinking in moderation vs. advice to stop drinking entirely. The goal is to see which approach better prevents major diseases and early death over time.
Pamplona, NavarreAges 50–75 - NCT06399835RecruitingPhase 4
Comparing two diabetes drugs for blood sugar and heart health
This study tests a new diabetes medicine called Enavogliflozin against an older drug, Pioglitazone, to see which works better for lowering blood sugar and improving heart health. If you have type 2 diabetes, take metformin plus another pill, and your A1C is between 7 and 10.5, this study may be an option for you.
Seongnam-si, Gyeonggi-doAges 20–80 - NCT06402747RecruitingPhase 4
Comparing clopidogrel vs cilostazol for diabetes-related artery thickening
This trial compares two blood-thinning drugs (clopidogrel and cilostazol) to see which one better prevents artery problems in people with diabetes and thickened carotid arteries. It may help you if you have diabetes and are already on stable medications.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06412536Recruiting
Heart, weight, and hormone trial screening survey
This trial is a quick survey to find out if you may be eligible for future studies on heart health, weight, or hormone-related conditions. It helps researchers match you with the right treatment options.
Brooklyn, New YorkAges 18 years+ - NCT06424106Recruiting
Glucagon & fasting insulin in people without type 2 diabetes
This study looks at how glucagon affects insulin release and blood sugar in people who do not have type 2 diabetes. It may help us understand normal glucose control better.
Rochester, MinnesotaAges 25–65 - NCT06462170Recruiting
Measuring insulin production in type 2 diabetes
This study tests how well your body makes insulin by having you drink a Boost shake and checking your blood. It's designed for people with type 2 diabetes who are not yet on insulin.
Ottawa, OntarioAges 18 years+ - NCT06482944Recruiting
Whole-food diet program for families to prevent type 2 diabetes
This 12-week program helps parents with prediabetes and their children eat healthier whole foods based on U.S. dietary guidelines. The goal is to see if the program can lower the risk of developing type 2 diabetes in the family.
Nashville, TennesseeAges 6–59 - NCT07693036RecruitingPhase 1/Phase 2
Exosomes from stem cells for type 2 diabetes
This trial tests if a type of stem cell product (exosomes) can safely and effectively help people with type 2 diabetes. Researchers will give infusions to see if it improves blood sugar control and pancreatic function.
BeijingAges 18–65 - NCT06526273Recruiting
PILI 'Āina Household Program
This study is for Native Hawaiian adults living in homestead communities who are overweight or have health conditions like diabetes, high blood pressure, or high cholesterol. It looks at a household-based program to help you and your family make healthier lifestyle changes together.
Honolulu, HawaiiAges 18 years+ - NCT06526650Recruiting
Cooking demos for Native Hawaiian adults with diabetes or heart risks
This trial tests if cooking demonstrations can help Native Hawaiian adults with conditions like type 2 diabetes, pre-diabetes, high blood pressure, or high cholesterol improve their health. You'd learn healthy cooking and be encouraged to do moderate activity like brisk walking.
Honolulu, HawaiiAges 18 years+
Hear when a new Type 2 diabetes trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for type 2 diabetes?
- Yes. Clin2 currently lists 1,078 recruiting type 2 diabetes studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a type 2 diabetes trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a type 2 diabetes trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.