Clinical trials
Ulcerative Colitis clinical trials
Below are recruiting ulcerative colitis clinical trials, each written for real people, not researchers. We’re tracking 280 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07470879RecruitingPhase 2
Etrasimod for Children with Ulcerative Colitis
This trial tests if the medicine etrasimod can help children with moderate to severe ulcerative colitis. You may still be able to join even if you are already taking other treatments for your condition.
New York, New YorkAges 2–11 - NCT07463183RecruitingPhase 2
Study of MK-8690 for moderate to severe ulcerative colitis
This trial tests an investigational drug called MK-8690 for people with moderate to severe ulcerative colitis (UC) who haven't responded well to other treatments or can't tolerate them. The study aims to see if the drug can help control UC symptoms safely.
Anaheim, CaliforniaAges 18–75 - NCT07442045Recruiting
Comparing combined vs single drug for ulcerative colitis
Researchers want to see if taking two medications together (upadacitinib and vedolizumab) works better than taking just upadacitinib alone for people with moderate to severe ulcerative colitis. This is a real-world study, meaning it looks at patients being treated in normal medical practice.
Foshan, GuangdongAges 18 years+ - NCT07415044RecruitingPhase 2
Study of LY4268989 for moderate to severe ulcerative colitis
This study tests an investigational medication called LY4268989 for adults with moderate to severe ulcerative colitis (UC). It's for people who have tried other treatments without success. The goal is to see if the drug can reduce inflammation and improve symptoms.
Phoenix, ArizonaAges 18–80 - NCT07389824Recruiting
Acupuncture plus mesalazine for ulcerative colitis
This study tests whether adding acupuncture (using small intradermal needles) to the standard medication mesalazine improves outcomes for people with mild-to-moderate ulcerative colitis. Participants receive 12 acupuncture sessions and undergo two colonoscopies to assess the treatment's effect.
Wuhan, HubeiAges 18–75 - NCT07374471RecruitingPhase 1/Phase 2
Testing MB-001 for moderate to severe ulcerative colitis
This study tests an investigational drug called MB-001 for people with moderate to severe ulcerative colitis who have already tried standard treatments without success. It aims to see if the drug is safe and helps control inflammation.
ChisinauAges 18–75 - NCT07347834Recruiting
Should you continue meds or have colitis surgery?
This trial studies whether continuing advanced medical treatments or having surgery (colectomy) is better for people with ulcerative colitis whose disease is active and hasn't improved after trying two or more advanced therapies.
Solna, Stockholm CountyAges 18 years+ - NCT07347158Enrolling by invitation
Health education for ostomy patients
This study teaches people with an ostomy (a surgical opening for waste) about their health to improve their quality of life and reduce anxiety or depression. If you are an adult with a permanent or long-term ostomy and live in the Santiago or Barbanza area, you may be able to join.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06213857RecruitingPhase 2
Silymarin for ulcerative colitis
This study tests whether silymarin (an extract from milk thistle) can help treat ulcerative colitis when added to your usual treatment. It may reduce inflammation and oxidative stress in the colon.
AsyutAges 18–65 - NCT07335055RecruitingPhase 2
Testing HSK47388 for moderate to severe ulcerative colitis
This study tests an experimental drug called HSK47388 for people with moderate to severe ulcerative colitis who have not had good results from other treatments. The goal is to see if it can reduce inflammation and improve symptoms.
HangzhouAges 18–75 - NCT07333716RecruitingPhase 2
Desloratadine for mild to moderate UC
This trial tests whether desloratadine, an allergy medicine (antihistamine), can help reduce inflammation in people with mild to moderate ulcerative colitis. All participants must already be taking mesalamine and cannot be on other stronger UC treatments.
Shibīn al Kawm, MenofiaAges 18–65 - NCT06595719Recruiting
Probiotics plus standard care for mild to moderate UC
This trial tests whether adding a multi-strain probiotic supplement to your usual care can help manage mild to moderate ulcerative colitis (UC). It lasts 12 weeks and requires you to stay on your current medications without changes.
Cheras, Kuala LumpurAges 18–90 - NCT07302360Recruiting
Guselkumab for ulcerative colitis in Chinese patients
This study tracks how well guselkumab (Tremfya) works in real-world Chinese patients with moderate to severe ulcerative colitis who haven't tried advanced therapies before. It helps doctors understand how the drug performs outside of controlled trials.
BeijingAges 18 years+ - NCT07296315RecruitingPhase 2
Testing a new treatment for mild-to-moderate ulcerative colitis
This study tests an investigational drug for people with active mild-to-moderate ulcerative colitis. It aims to see if the drug can improve symptoms without needing advanced treatments like biologics.
Miami, FloridaAges 16 years+ - NCT07271069Recruiting
Ozanimod vs azathioprine for steroid-dependent ulcerative colitis
This study tests whether ozanimod works better than azathioprine in people with ulcerative colitis who need high-dose steroids. Both groups also stay on steroids. The goal is to see if either drug helps you reduce or stop steroids while keeping symptoms under control.
Chiba, ChibaAges 18 years+ - NCT07258771RecruitingPhase 4
Upadacitinib plus steroids vs steroids alone for severe ulcerative colitis
This trial tests if adding upadacitinib (a pill) to standard steroid treatment helps people with a severe flare of ulcerative colitis feel better faster. You may qualify if you are having frequent bloody stools and signs of serious inflammation, and you haven't tried upadacitinib before.
Ann Arbor, MichiganAges 18–75 - NCT07243639Recruiting
Etrasimod for elderly patients with ulcerative colitis
This trial tests an oral medication called etrasimod for elderly patients with active ulcerative colitis. It aims to see if the drug is safe and effective in reducing inflammation and symptoms.
Komagane, NaganoAges Any age - NCT07235904RecruitingPhase 4
Mirikizumab vs standard treatment for newly diagnosed ulcerative colitis
This trial tests if starting with the stronger drug mirikizumab (top-down therapy) works better than the usual treatment with azathioprine for people newly diagnosed with moderate-to-severe ulcerative colitis. It aims to see which approach controls inflammation and improves symptoms faster.
KielAges 18–75 - NCT06895252Recruiting
Fecal transplant and diet for new ulcerative colitis
This study tests whether a combination of fecal transplant (transferring healthy stool into your gut) and dietary changes can help control inflammation in people recently diagnosed with active ulcerative colitis. It may offer a new treatment option before starting stronger medications.
Kochi, KeralaAges 18–75 - NCT07196748RecruitingPhase 3
Icotrokinra for adults and teens with moderate to severe ulcerative colitis
This trial tests a new oral medication, icotrokinra, for people with moderately to severely active ulcerative colitis. It may be an option if you have not responded well enough to standard treatments or newer advanced therapies.
Chandler, ArizonaAges 12 years+ - NCT07186101RecruitingPhase 2
Testing a new combo therapy for ulcerative colitis
This study tests two drugs together (LY4268989 and mirikizumab) in people with moderate to severe ulcerative colitis. It's for those whose current treatments didn't work well enough.
Scottsdale, ArizonaAges 18–80 - NCT07184996RecruitingPhase 3
Study of duvakitug for moderate to severe ulcerative colitis
This study tests a new drug called duvakitug for people with moderate to severe ulcerative colitis that hasn't been helped enough by standard treatments. The goal is to see if this medicine can reduce inflammation and improve symptoms.
Peoria, ArizonaAges 16–80 - NCT07154784Enrolling by invitationPhase 2/Phase 3
Fecal transplant for long-term ulcerative colitis treatment
This trial tests whether fecal microbiota transplantation (FMT) can safely and effectively treat mild to moderate ulcerative colitis over the long term. FMT involves transferring stool from a healthy donor to restore a healthy balance of gut bacteria.
Seoul, Dongjak-guAges 10–80 - NCT07136116Recruiting
Study of risankizumab for moderate to severe ulcerative colitis in Japan
This study looks at how well risankizumab (an injected medicine) works for people with moderate to severe ulcerative colitis. It tracks your symptoms using a mobile app to see if the drug helps control the disease.
Nagakute, Aichi-kenAges 15 years+
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Common questions
- Are there clinical trials for ulcerative colitis?
- Yes. Clin2 currently lists 280 recruiting ulcerative colitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a ulcerative colitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a ulcerative colitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.