Clinical trials
Urinary Bladder Cancer clinical trials
Below are recruiting urinary bladder cancer clinical trials, each written for real people, not researchers. We’re tracking 163 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07061964RecruitingPhase 2
Immunotherapy and radiation to save the bladder
This trial tests whether combining immunotherapy and low-dose radiation after chemotherapy can help you avoid bladder removal. It's for people whose muscle-invasive bladder cancer has shrunk significantly after initial treatment.
Birmingham, AlabamaAges 18 years+ - NCT07784387Recruiting
Bladder cancer study in Portugal
This study looks at the characteristics and outcomes of people with high-risk non-muscle-invasive bladder cancer in Portugal. It aims to understand the disease better and could help improve future treatments.
LisbonAges 18 years+ - NCT07222488RecruitingPhase 1/Phase 2
Study of MK-3120 for bladder cancer
This trial tests a new drug, MK-3120, for people with a specific type of bladder cancer that hasn't spread into the muscle. It is for patients who either haven't had BCG treatment before or have had BCG treatment and their cancer came back more than 12 months but within 2 years after the last dose.
Bakersfield, CaliforniaAges 18 years+ - NCT07187635Recruiting
Urine DNA test before a second bladder tumor surgery
This trial studies if a urine test for tumor DNA can help decide when a second surgery is needed for early stage bladder cancer. It may reduce unnecessary procedures for some patients.
Nanchang, AnhuiAges 18 years+ - NCT04752722RecruitingPhase 1/Phase 2
Gene therapy for bladder cancer that came back after BCG
This study tests a new gene therapy (EG-70) given directly into the bladder for people with a high-risk bladder cancer called NMIBC. It may be an option if BCG treatment stopped working, or if you cannot have or choose not to have bladder removal surgery.
Birmingham, AlabamaAges 18 years+ - NCT07566156RecruitingPhase 3
New drug combination vs. radiation for bladder cancer preservation
This trial tests whether two drugs (enfortumab vedotin and pembrolizumab) work better than radiation with chemotherapy for muscle-invasive bladder cancer. The goal is to treat your cancer while keeping your bladder instead of removing it.
Santa Barbara, CaliforniaAges 18 years+ - NCT06289270Recruiting
Bladder cancer and urine bacteria study
This study looks at bacteria in urine and the bladder to understand if they play a role in causing bladder cancer. Researchers will compare samples from men with bladder cancer and healthy controls.
Cairo, Giza GovernorateAges 18 years+ - NCT05792033Recruiting
Registry for early T1 bladder cancer after repeat bladder surgery
This study follows people with newly diagnosed early bladder cancer (T1) to better understand outcomes and guide follow-up care. You may be able to join if your cancer is confirmed after a second look bladder procedure and scans show no spread.
ViennaAges 18–90 - NCT07747740RecruitingPhase 2
Bladder cancer treatment after BCG therapy fails
This trial compares two combinations of chemotherapy drugs given directly into the bladder to see which works better for patients whose bladder cancer has not responded to BCG therapy.
Moscow, MoscowAges 18 years+ - NCT06465069RecruitingPhase 1
Study of a new drug for advanced bladder and other solid tumors
This study tests a new drug (LY4052031) for people with several types of advanced solid tumors, especially bladder cancer. It aims to see if the drug is safe and effective when given alone or after other treatments have stopped working.
Duarte, CaliforniaAges 18 years+ - NCT05796375RecruitingPhase 2
Urine testing instead of repeat bladder scope checks
This Phase 2 study tests whether urine tests can help monitor “non-muscle-invasive” bladder cancer without doing as many invasive bladder scopes (cystoscopies). If you qualify, you may be able to replace some scope visits with urine sample testing while still keeping close watch for cancer coming back.
West Haven, ConnecticutAges 18 years+ - NCT07721935Recruiting
AI tool for urological disease diagnosis and treatment
This trial is testing an artificial intelligence (AI) system that helps doctors diagnose and treat urological conditions like urinary stones, prostate cancer, or bladder cancer. It looks at your medical records, scans, and surgical videos to improve care.
Guangzhou, GuangdongAges Any age - NCT03193541Recruiting
Testing a urine blood test to check for bladder cancer risk
This trial checks whether a new lab test on urine can help sort out which people with small amounts of blood in the urine (microscopic hematuria) might have bladder cancer. It may help doctors evaluate symptoms more accurately and decide who needs further testing.
Long Beach, CaliforniaAges 18–90 - NCT03379909RecruitingPhase 2
Metformin taken by mouth for early bladder cancer
This trial studies whether a diabetes medicine called metformin can help prevent or control non-muscle-invasive bladder cancer inside the bladder. You would take it by mouth, and the study checks safety and whether it works.
Nijmegen, GelderlandAges 18 years+ - NCT03844256RecruitingPhase 1/Phase 2
Bladder-sparing chemo-radiation plus immunotherapy for bladder cancer
This study tests whether adding immunotherapy drugs (nivolumab alone or nivolumab plus ipilimumab) to standard chemo-radiation can control muscle-invasive bladder cancer while helping people keep their bladder. It aims to find a safer, effective curative treatment for people who want to avoid bladder removal (cystectomy).
Amsterdam, North HollandAges 18 years+ - NCT03973671Recruiting
Collecting blood and tissue samples during bladder cancer surgery
This study collects clinical and tissue samples from people who are having surgery for bladder cancer and related urinary-tract tumors. It aims to improve understanding of cancer and may help future care by building a large research dataset.
Leuven, Vlaams-BrabantAges 18–90 - NCT06580002RecruitingPhase 2
Can Riluzole Help with Chemo Brain? A Pilot Study
This study tests if a medicine called riluzole (currently used for ALS) can help with 'chemo brain' – memory and thinking problems after cancer treatment. It is for people who feel their mental sharpness has declined after breast cancer therapy, certain chemotherapies, or brain radiation.
Orange, CaliforniaAges 18 years+ - NCT04106115RecruitingPhase 1/Phase 2
Durvalumab vaccine trial for high-risk bladder cancer after BCG
This early-phase trial tests durvalumab given with an experimental bladder cancer vaccine to help stop or slow high-risk bladder cancer that did not respond to or cannot be treated with BCG. It also evaluates safety and how well the treatment works in this setting.
CambridgeAges 18 years+ - NCT04369560RecruitingEarly Phase 1
Virtual MRI to map bladder cancer for staging before surgery
This early-stage study uses special MRI imaging to create a “virtual view” of the bladder wall so doctors can better stage bladder cancer before treatment. If you qualify, you may get MRI imaging using contrast medicines as part of planning your surgery.
Pittsburgh, PennsylvaniaAges 18–90 - NCT04442724Recruiting
MRI and bladder marker planning to guide bladder chemoradiation
This trial uses special MRI scans and tiny markers placed in the bladder to better plan bladder chemoradiation. The goal is to help target treatment more accurately and improve how well it can be delivered.
Los Angeles, CaliforniaAges 18 years+ - NCT04498767Recruiting
Radiation to treat a few metastatic spots in rare cancers
This trial studies whether stereotactic (high-precision) radiation given in a few sessions can control rare cancers that have spread to a small number of sites. It aims to help by treating all known spots while keeping side effects manageable.
AnderlechtAges 18 years+ - NCT04861584RecruitingPhase 2
Immunotherapy plus chemo before bladder surgery for advanced cancer
This trial studies giving toripalimab (an immunotherapy) together with gemcitabine and cisplatin before bladder surgery. It aims to shrink locally advanced bladder cancer and make surgery more effective by using the immune system and chemotherapy together.
Guangzhou, GuangdongAges 18–75 - NCT04947059RecruitingPhase 3
Stop bladder cancer coming back with medicine after bladder surgery
This trial tests whether putting chemotherapy medicine directly into the bladder right after surgery helps prevent bladder cancer from coming back. It compares gemcitabine versus epirubicin given as an immediate bladder “wash-in.”
Larissa, Larissa/ThessalyAges 18–100 - NCT05037279RecruitingPhase 3
Testing BCG treatment for bladder cancer after full tumor removal
This trial studies a BCG-based bladder instillation in people with newly diagnosed, intermediate- or high-risk non-muscle invasive bladder cancer who have had their tumor fully removed. The goal is to see whether this treatment is safer and works better to lower the chance of the cancer coming back.
Vancouver, British ColumbiaAges 18 years+
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Common questions
- Are there clinical trials for urinary bladder cancer?
- Yes. Clin2 currently lists 163 recruiting urinary bladder cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a urinary bladder cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a urinary bladder cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.