Clinical trials
Vagus Nerve Stimulation clinical trials
Below are recruiting vagus nerve stimulation clinical trials, each written for real people, not researchers. We’re tracking 155 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05588063Recruiting
Device-based nerve stimulation for relapse-preventing kidney disease in kids
This trial tests whether a small non-surgical device can help keep children with steroid-sensitive nephrotic syndrome in remission. If it works, it could lower the chance of relapse (kidney flare-ups) and help maintain kidney health.
New Hyde Park, New YorkAges 3–17 - NCT05554172Recruiting
Non-invasive vagus nerve stimulation during refeeding for low weight
This study tests whether a painless device that stimulates the vagus nerve can help teens who are underweight and working on refeeding (a structured nutrition plan). It aims to see if this treatment improves outcomes while you’re gaining weight.
New York, New YorkAges 14–22 - NCT05583942Recruiting
Nerve stimulation trial for children with steroid-resistant kidney syndrome
This pilot study tests a device that stimulates nerves in the ear to help children with steroid-resistant nephrotic syndrome. It may improve urine protein and kidney-related outcomes for kids whose standard steroid treatment does not work.
New Hyde Park, New YorkAges 3–17 - NCT05103566Recruiting
Noninvasive vagus nerve stimulation for ruptured brain aneurysm bleed
This trial studies whether a noninvasive device that stimulates the vagus nerve can be safely given soon after a ruptured aneurysm bleed to improve outcomes. It may help calm the brain’s stress response after this type of stroke-like emergency.
Boston, MassachusettsAges 18–85 - NCT03992378Recruiting
Nerve stimulation to calm inflammation in sepsis
This trial tests a form of nerve stimulation to help control the body’s overactive inflammation and “autonomic” nervous system imbalance during sepsis. It may help stabilize blood pressure and reduce complications, depending on the cause of your symptoms.
Oklahoma City, OklahomaAges 18 years+ - NCT07857499Recruiting
Nerve stimulation plus exercise for lipedema leg pain
This trial tests whether a gentle nerve stimulation device worn on the ear, combined with exercise, can reduce leg pain and swelling in women with lipedema. It aims to improve how well standard rehabilitation works for this condition.
Istanbul, EyupsultanAges 18–65 - NCT06433583Recruiting
Ear nerve stimulation for teens who self-harm
This study tests whether a tiny device that gently stimulates a nerve in your ear (called the vagus nerve) is acceptable to teens who hurt themselves without meaning to die. The goal is to see if teens find it comfortable and easy to use, which could lead to a new way to help manage urges.
ThionvilleAges 13–18 - NCT06016686RecruitingPhase 1
Recording nerve signals from the vagus nerve in awake humans
This study tests a new way to listen to the vagus nerve in awake people. It may help understand how the nerve controls body functions like heart rate and digestion.
Minneapolis, MinnesotaAges 18–40 - NCT05870527Enrolling by invitation
Pupil changes during vagus nerve stimulation during ear surgery
This study looks at how your pupils (the black center of the eye) respond while a vagus nerve device is turned on during surgery for either a cochlear implant or a vagus nerve stimulator. It aims to better understand the eye/nerve effects of this stimulation, which may improve how such procedures are done safely.
New York, New YorkAges 18 years+ - NCT07831876RecruitingPhase 1
Ear nerve stimulation for eye inflammation
This study tests whether gently stimulating a nerve in the ear can help reduce swelling or irritation in the eyes. It may offer a new drug-free way to treat certain types of eye inflammation.
Basking Ridge, New JerseyAges 18 years+ - NCT05694663Recruiting
Vagus nerve stimulation to aid stroke recovery
This registry looks at people with a prior ischemic stroke to see how a device that stimulates the vagus nerve may support arm recovery. If you are planning to get the implant and can follow the program steps, your information may be followed to track progress and safety.
New York, New YorkAges 18 years+
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Common questions
- Are there clinical trials for vagus nerve stimulation?
- Yes. Clin2 currently lists 155 recruiting vagus nerve stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vagus nerve stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vagus nerve stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.