Clinical trials
Vagus Nerve Stimulation clinical trials
Below are recruiting vagus nerve stimulation clinical trials, each written for real people, not researchers. We’re tracking 158 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07218133Recruiting
Ear Stimulation to Reduce Pain After Spine Surgery
This trial tests whether a gentle electrical stimulation delivered through the ear can reduce inflammation and pain after major spinal fusion surgery. If you are having a long spinal fusion, you might be able to join.
St Louis, MissouriAges 18 years+ - NCT07600424Recruiting
Ear Stimulation Device for Moderate to Severe Facial Redness
This trial tests a small device worn on your ear that sends gentle electrical signals to a nerve, aiming to reduce facial redness and flushing from rosacea. The device may help calm the inflammation that causes rosacea symptoms.
Boston, MassachusettsAges 18 years+ - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT07761507Recruiting
Ear stimulation to help wake up after brain bleed surgery
This trial tests a gentle ear stimulation device that may help people regain consciousness after surgery for a brain bleed. It is done while the person is in the hospital and may improve recovery.
BeijingAges 18–75 - NCT05725239Recruiting
Testing vibration or magnetic stimulation for depression
This study tests whether taVNS, TMS, or both can improve depression symptoms. It may help people whose depression has not improved enough with usual treatments like antidepressant pills or talking therapy.
Charleston, South CarolinaAges 18–75 - NCT07636304Enrolling by invitationEarly Phase 1
Brain stimulation for inflammatory bowel disease remission
This study tests whether a non-invasive device that stimulates the vagus nerve (a major nerve in your neck) can affect brain function in people whose IBD is in remission. Researchers want to understand if this stimulation might help reduce inflammation or improve symptoms in the future.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT06759818Enrolling by invitation
Vagus nerve stimulation for heart protection after lung surgery in older adults
This trial tests if a gentle ear stimulation device can protect the heart after lung surgery in patients aged 60 and older. It is for those having a planned lung procedure (lobectomy, segmentectomy, or wedge resection) through small chest incisions.
Jiaxing, ZhejiangAges 60 years+ - NCT05090267Recruiting
Gut-brain treatments for alcohol use and memory changes
This study tests whether gut-brain–targeted treatments (including probiotics and stimulation of a nerve) can improve thinking and inflammation-related health in people who use alcohol. You may be able to join if you have memory/thinking problems and meet specific medical limits, including HIV immune system levels.
Coral Gables, FloridaAges 35–70 - NCT06742788Recruiting
Vagus nerve stimulation for IVF patients with anxiety or depression
This trial tests whether a gentle form of nerve stimulation (taVNS) can improve pregnancy rates in women undergoing IVF who also have mild-to-moderate anxiety or depression. It aims to see if this treatment is both helpful and practical for this group.
Xi'an, ShaanxiAges 20–40 - NCT07000175Recruiting
Heart rate measurement on arm vs. chest during nerve stimulation
This study compares two ways of measuring heart rate variability (a sign of how well your nervous system is working) during a gentle nerve stimulation therapy. It looks for healthy volunteers to see if a simple arm measurement works as well as a chest measurement.
Trabzon, OrtahisarAges 18–45 - NCT06421051Recruiting
Ear nerve stimulation for better sleep after surgery in older adults
This study tests whether gentle electrical stimulation of a nerve in the ear can help older adults sleep better after surgery. It's for people 65 and older having planned surgeries that don't involve the brain.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06287970Recruiting
Testing a nerve stimulation device for chronic pelvic pain
This trial tests if a non-invasive nerve stimulation device (TaVNS) can reduce pain, urinary symptoms, and mood issues in men with moderate to severe chronic pelvic pain syndrome (CP/CPPS). It may offer a new drug-free option for symptom relief.
Beijing, Beijing MunicipalityAges 18–50 - NCT07529392Recruiting
Ear nerve stimulation plus rehabilitation for chronic back pain
This trial tests a non-surgical treatment that stimulates a nerve in your ear while you do rehabilitation exercises to reduce chronic back pain. It may help if you've had pain for more than 6 months and pain medications aren't working well enough.
Baden, Lower AustriaAges 30–65 - NCT07548723Enrolling by invitation
Nerve Stimulation Device Reliability Study
This study tests how reliably a small ear-stimulation device measures heart-rhythm patterns. Researchers want to see if the device gives consistent readings across multiple measurement sessions, which could help doctors monitor heart health in the future.
SinopAges 18–40 - NCT06421077Recruiting
Ear nerve stimulation to prevent confusion after surgery in older adults
This trial tests if a gentle electrical stimulation on the ear can help prevent postoperative delirium (sudden confusion) in older patients after surgery. It focuses on people 65 and older who will have longer operations.
BeijingAges 65 years+ - NCT07574580Enrolling by invitation
Vagus Nerve Stimulation for Acute Burn Injury Recovery
This trial tests a non-invasive device that stimulates the vagus nerve (a major nerve in your body) through your ear to help reduce inflammation and pain after severe burns. The goal is to see if this can speed healing and improve recovery in patients with moderate to severe burn injuries.
Istanbul, KartalAges 18–65 - NCT07486804Recruiting
Brain stimulation to help teens who self-injure
This study tests if a gentle, non-invasive brain stimulation technique (like wearing a special cap) can help teenagers who hurt themselves on purpose. It compares two types of stimulation to see which one reduces the urge to self-injure.
Hefei, AnhuiAges 12–22 - NCT07482930Recruiting
Nerve stimulation and breathing test study in healthy adults
This study tests if a gentle nerve stimulation device placed on the ear can change how you breathe during a lung function test. It is only for healthy volunteers aged 18–40 who have no heart, lung, nerve, or mental health conditions.
SinopAges 18–40 - NCT07420803Recruiting
Nerve stimulation study for chronic dizziness
This study tests if a gentle, non-invasive nerve stimulation in the ear can help reduce chronic dizziness. It is for people with a specific type of dizziness called PPPD that has lasted at least 3 months.
Jacksonville, FloridaAges 18 years+ - NCT06957912Recruiting
Ear nerve stimulation for recovery after major surgery
This trial tests if stimulating a nerve in your ear (vagus nerve) before and after noncardiac surgery can improve your recovery. It's for adults aged 18 to 84 having planned or time-sensitive surgery lasting at least 2 hours.
Beijing, Beijing MunicipalityAges 18–85 - NCT07681336Recruiting
Ear nerve stimulation for chronic low back pain
This trial tests if stimulating the vagus nerve through the ear can reduce chronic low back pain in people who haven't gotten enough relief from painkillers. It aims to see if this non-invasive treatment can help manage pain without medication.
Ghent, Oost-VlaanderenAges 30–60 - NCT06623721Enrolling by invitation
Ear stimulation during movement for stroke and injury recovery
This study tests a gentle ear stimulation device that activates a nerve when you move your arm or leg, to see if it helps your recovery after a stroke or brain/spinal cord injury. If you still have some weakness, this could be a way to boost your rehabilitation.
WeggisAges 18 years+ - NCT07055373Recruiting
Nerve stimulation for chronic whiplash pain
This trial tests if a gentle nerve stimulation device on the ear can reduce neck pain and disability in people with long-term whiplash symptoms. It aims to find a safe, non-drug option for pain relief.
Calgary, AlbertaAges 18–65 - NCT07619989Recruiting
Ear nerve stimulation for weight loss after tirzepatide
This trial tests if a gentle electrical stimulation to the ear can help people who haven't lost much weight with tirzepatide (a diabetes/weight drug). It's for people who are still overweight after 12 weeks of treatment.
Nanjing, JiangsuAges 18–50
Hear when a new Vagus Nerve Stimulation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for vagus nerve stimulation?
- Yes. Clin2 currently lists 158 recruiting vagus nerve stimulation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a vagus nerve stimulation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a vagus nerve stimulation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.