Treatment
Biologic Therapy clinical trials
We’re tracking 60 recruiting studies that include Biologic Therapy, each written for real people, not researchers, below.
Recruiting studies
- NCT05169593RecruitingPhase 4
Prevent Crohn’s return after surgery: endoscopy-guided vs standard medicine
This study compares two ways to choose biologic (targeted) medicines after Crohn’s surgery to help stop Crohn’s from coming back in the bowel. It may help you avoid or delay repeat inflammation by adjusting treatment based on endoscopy findings.
Antwerp, AntwerpenAges 18–80 - NCT06669702Recruiting
Exercise therapy for axial spondyloarthritis on biologics
This study tests whether a supervised exercise program can help people with axial spondyloarthritis (a type of inflammatory arthritis affecting the spine) who are already on biologic medications. It aims to see if exercise reduces inflammation and improves symptoms.
Loughborough, LeicestershireAges 18 years+ - NCT06882148Recruiting
How long do eczema patients stay on targeted therapies?
This study looks at how long people with moderate to severe eczema stay on newer targeted medicines (biologics or pills). By reviewing medical records, researchers hope to learn which treatments work best over time and how they are used in real life.
RomeAges 18 years+ - NCT06686082Enrolling by invitation
Biologic therapy for early psoriatic arthritis
This study looks at whether starting biologic treatments early, even before joint pain appears, can help people with psoriasis who have signs of joint inflammation on ultrasound. You may be eligible if you have moderate to severe psoriasis but no joint symptoms yet.
Fuzhou, FujianAges 18 years+ - NCT07475052Enrolling by invitation
Heart rate monitoring to predict biologic therapy response in IBD
This study tests whether a wearable heart rate monitor can help predict how well biologic medications work for people with Crohn's disease or ulcerative colitis. If you are starting infliximab or vedolizumab for the first time, you may be eligible.
Xi'an, ShaanxiAges 18–75 - NCT07212933RecruitingPhase 2
RAK cell therapy for advanced stomach cancer
This trial tests a new type of immune cell therapy called RAK cells for people with late-stage stomach cancer that has spread and stopped responding to standard treatments. The goal is to see if it is safe and helps control the cancer.
Beijing, Beijing MunicipalityAges 18–70 - NCT06314087RecruitingPhase 2
Personalized cancer vaccine with radiation therapy
This trial tests a personalized cancer vaccine combined with a special type of radiation therapy for people with advanced or recurrent cancers that no longer respond to standard treatments. The goal is to help your immune system better recognize and attack your cancer.
Shenzhen, GuangdongAges 18–80 - NCT07187583RecruitingPhase 4
Reducing biologic doses for chronic sinusitis with polyps
This trial tests if patients with chronic sinusitis and nasal polyps can safely reduce how often they take their biologic medication (dupilumab or mepolizumab) after their disease has been partly controlled for at least a year.
AalborgAges 18 years+ - NCT04372108Recruiting
Long-term safety study for ustekinumab vs other biologics
This study follows adults with Crohn’s disease or ulcerative colitis to compare the long-term safety of ustekinumab against other biologic medicines. It may help show how safe these treatments are over time, using medical records.
Portsmouth, VirginiaAges 18 years+ - NCT06927466RecruitingPhase 1
B019 for relapsed or refractory B-cell acute lymphoblastic leukemia
This trial tests a new treatment called B019 for people whose B-cell acute lymphoblastic leukemia has come back or not responded to standard therapy. The treatment targets specific proteins on the cancer cells to help your immune system fight the leukemia.
BeijingAges 3–25 - NCT04115267Recruiting
Registry study tracking side effects from radiation and medicines
This study follows people with cancer to better understand which treatments cause certain side effects when radiation is combined with targeted (molecular) medicines. Your participation may help doctors predict and manage side effects more safely in the future.
Montreal, QuebecAges 18 years+ - NCT07755670Recruiting
Brain scans to understand hidradenitis suppurativa
This study uses MRI brain scans to see if brain activity differs in people with hidradenitis suppurativa (a painful skin condition) compared to healthy volunteers. It also tracks how treatment affects the brain over 3 months.
Changsha, HunanAges 18–45 - NCT07202000RecruitingPhase 2
Exercise and a drug to reduce inflammation for heart failure with preserved ejection fraction
This trial tests whether combining exercise with a medication that blocks a protein called activin can reduce inflammation, improve heart function, and help with thinking in people with heart failure with preserved ejection fraction (HFpEF).
Boston, MassachusettsAges 40 years+ - NCT07721441Enrolling by invitation
Predicting Gut Healing in Ulcerative Colitis with a Stool Test
This study looks at whether a simple stool test can tell if treatment is healing the gut lining in people with moderate to severe ulcerative colitis who are starting their first biologic medicine. If it works, this test might help doctors adjust treatment earlier.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06899204Recruiting
Abrocitinib for atopic dermatitis after biologic therapy
This study looks at how well abrocitinib (a daily pill) works for people with moderate to severe eczema who have already tried biologic medicines and didn't get enough relief. It aims to see if this treatment can help you better manage your eczema.
San Diego, CaliforniaAges 12 years+ - NCT03968913RecruitingEarly Phase 1
Biologic shot to prevent knee arthritis after ACL injury
This early-phase trial tests a biologic medicine (anakinra) given after an ACL injury to try to prevent or reduce later osteoarthritis (wear-and-tear arthritis). It enrolls young adults who recently tore their ACL and are planning a specific type of ACL reconstruction.
Los Angeles, CaliforniaAges 18–35 - NCT04331639Recruiting
High-dose vitamin D for kids with IBD on biologic therapy
This trial studies whether giving a higher dose of vitamin D3 helps children and teens with inflammatory bowel disease (Crohn’s or ulcerative colitis) who have low vitamin D levels. Participants are already on biologic medicines and will be treated while monitoring blood (and safety) related to vitamin D.
Boston, MassachusettsAges 5–25 - NCT06447870Recruiting
Why Some IBD Treatments Don't Work: A Multi-Omics Study
This study looks at why some people with inflammatory bowel disease (Crohn's or ulcerative colitis) do not respond to certain biologic treatments. Researchers will use advanced testing (multi-omics) to better understand treatment response. If you are starting or have just started treatment with infliximab, adalimumab, vedolizumab, or ustekinumab, you may be able to join.
Guangzhou, GuangdongAges 18 years+ - NCT06954311Recruiting
Drug monitoring for children with IBD
This study monitors levels of certain medications (infliximab, adalimumab, vedolizumab, ustekinumab) in children with inflammatory bowel disease to see if adjusting the dose helps them feel better. It aims to improve treatment outcomes.
FeldkirchAges birth–18 years - NCT07678112Recruiting
Trial of a device to keep rheumatoid arthritis in remission
This trial tests a medical device to help people with rheumatoid arthritis stay in remission while on biologic therapy. The goal is to see if the device can prevent flares and maintain disease control.
A Coruña, A CoruñaAges 18 years+ - NCT01965132Recruiting
Biologic and targeted therapy registry for arthritis patients
This registry is collecting information about people with rheumatoid arthritis, ankylosing spondylitis, or psoriatic arthritis who are starting or needing biologic or targeted medicines. It may help researchers better understand how these treatments work in real life.
SeoulAges 18 years+ - NCT06014827RecruitingPhase 2
Targeted radiation and osimertinib for lung cancer with EGFR mutation
This trial tests a new approach for patients with advanced non-small cell lung cancer that has a specific EGFR mutation (Ex19del or L858R) and has started to grow again after at least six months on osimertinib. It combines two types of focused radiation with continued osimertinib to treat only the progressing spots while keeping the rest of the disease under control.
Duarte, CaliforniaAges 18 years+ - NCT07722494RecruitingPhase 3
Investigational drug plus bevacizumab for advanced colorectal cancer
This trial tests a new drug combined with a standard treatment for advanced colorectal cancer that has not responded to earlier therapies. It aims to see if the combination can help slow the cancer's growth.
Wuhan, WuhanAges 18 years+ - NCT06678022Recruiting
Using medical drones to deliver HIV treatment in Kalangala
This study tests whether medical drones can safely deliver HIV medications and lab samples in remote areas. If successful, it could help people living with HIV get their medicine faster and more reliably.
Kalangala, SseseAges 15 years+
What Biologic Therapy is being studied for
Conditions with recruiting Biologic Therapy studies.
Common questions
- Are there clinical trials studying Biologic Therapy?
- Yes. Clin2 currently lists 60 recruiting studies that include Biologic Therapy, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Biologic Therapy trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Biologic Therapy an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Biologic Therapy or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.