Treatment
Low Dose clinical trials
We’re tracking 459 recruiting studies that include Low Dose, each written for real people, not researchers, below.
Recruiting studies
- NCT06724640RecruitingPhase 1
Safety study of an experimental HIV prevention drug in healthy adults
This study tests a new injectable drug (VH4011499) for safety and how the body processes it. It's for healthy adults without HIV, and participants will get either the study drug or a placebo (an inactive shot).
Las Vegas, NevadaAges 18–55 - NCT06782529RecruitingPhase 4
Knee injection study for patients with obesity and arthritis
This study tests if steroid injections for knee arthritis work in people with obesity. It may help you manage pain and avoid surgery.
Jacksonville, FloridaAges 55–85 - NCT07171359Recruiting
TMS therapy for opioid and alcohol use recovery
This trial tests whether TMS (a non-invasive brain stimulation) can improve recovery for people with both opioid and alcohol use disorders. You must be in a specific outpatient program in Portland, Oregon.
Portland, OregonAges 18 years+ - NCT07176091Enrolling by invitation
Magnetic brain stimulation for Parkinson's disease pain
This trial tests a special type of magnetic brain stimulation (called TMS) to see if it can help with Parkinson's disease and the pain that often comes with it. You must have had Parkinson's for at least 3 years, have frequent pain, and be on stable medications.
Suzhou, JiangsuAges 40–80 - NCT07191483RecruitingPhase 2
Study of KYN-5356 for cognitive problems in schizophrenia
This trial tests an investigational drug, KYN-5356, to see if it can improve thinking and memory problems in adults with schizophrenia. You may join if your schizophrenia is stable and you take only one antipsychotic medication.
Little Rock, ArkansasAges 18–55 - NCT07400965RecruitingPhase 2
Testing a new eye drop for eyelid inflammation caused by tiny mites
This trial tests an investigational eye drop (GLK-321) to see if it safely and effectively treats Demodex blepharitis, an eyelid inflammation caused by tiny mites. It may help people who have signs of this condition and good enough vision.
Newport Beach, CaliforniaAges 18 years+ - NCT06963125Recruiting
Prune juice for constipation in older adults
This study tests whether drinking prune juice can improve bowel movements, reduce constipation symptoms, and enhance quality of life in older adults who have trouble going to the bathroom regularly.
Chiayi City, Chiayi CountyAges 65–100 - NCT07193901RecruitingPhase 2
Nasal spray for depression with suicidal thoughts
This trial tests an experimental nasal spray for people with major depression who are currently having suicidal thoughts. It aims to see if the spray can quickly reduce depression and suicidal feelings.
BeijingAges 18–64 - NCT07240896RecruitingEarly Phase 1
Testing a new mRNA therapy for Wilson disease
This trial tests an experimental mRNA treatment (DSL101) for adults with Wilson disease. It's for people whose condition is stable on current therapy and who have certain genetic markers. The goal is to see if the new treatment can help the body process copper better and reduce the need for standard medicines.
Hefei, AnhuiAges 18 years+ - NCT07643844RecruitingPhase 1
Gene therapy for propionic acidemia in infants
This trial tests a new gene therapy treatment designed to help the body process certain amino acids better in infants with propionic acidemia. The therapy uses a modified virus to deliver a working copy of a faulty gene, potentially reducing dangerous acid buildups and hospital visits.
Rochester, MinnesotaAges 6 months–2 years - NCT06275620Enrolling by invitationPhase 2
Testing a gene therapy for X-linked retinitis pigmentosa in males
This trial tests two doses of a gene therapy (AGTC-501) in males who already had one eye treated with a similar gene therapy for X-linked retinitis pigmentosa caused by RPGR mutations. The goal is to see if the treatment is safe and can help preserve or improve vision.
Jacksonville, FloridaAges 12 years+ - NCT07469072RecruitingPhase 2
Nafamostat doses for dialysis blood thinning in ICU
This trial is testing different doses of a blood thinner called nafamostat in patients who are in the ICU and need continuous kidney dialysis (CRRT). The goal is to find which dose works best to prevent clots in the dialysis machine without causing bleeding problems.
Guangzhou, GuangdongAges 18–80 - NCT06686030RecruitingPhase 2
AK112 with chemo or olaparib for platinum-sensitive ovarian cancer
This trial tests a new drug called AK112 combined with chemotherapy or another drug (olaparib) for people with ovarian cancer that came back more than 6 months after platinum treatment. The goal is to see if these combinations work better than current options.
WuhanAges 18 years+ - NCT05420779RecruitingPhase 2
TSL-1502 for breast cancer with BRCA gene mutations
This Phase 2 trial tests TSL-1502 capsules, a targeted medicine for breast cancer, in people whose blood test shows a harmful BRCA gene mutation. It aims to see whether it can control the cancer and how safe it is after prior treatment.
BeijingAges 18–75 - NCT07039578RecruitingPhase 2
Study of CM336 for light-chain amyloidosis
This trial tests a new injection called CM336 for people with light-chain amyloidosis that has come back or not responded to other treatments. It aims to see if the drug is safe and effective.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07127042RecruitingPhase 2
Testing a drug to reduce bleeding during knee replacement
This trial tests an experimental drug called BT-114143 to see if it reduces bleeding during and after total knee replacement surgery. It may be a good option for people with osteoarthritis who are having their first knee replacement.
Chengdu, Si'ChuanAges 18–70 - NCT07710248RecruitingPhase 2
Safety of SG301-SC in adults with ITP
This study tests a new injection called SG301-SC for people with primary immune thrombocytopenia (ITP) whose platelet counts stay low even after standard treatments. The goal is to see if it is safe and helps raise platelets, reducing bleeding risk.
Fuzhou, FujianAges 18–75 - NCT03383081RecruitingPhase 2
Stem cell injection for moderate knee osteoarthritis pain
This Phase 2 study tests whether injected umbilical-cord stem cells can improve safety and reduce symptoms in people with moderate knee osteoarthritis. It focuses on people with significant knee pain who have not gotten enough relief from standard, non-procedure treatments.
Changsha, HunanAges Up to 70 years - NCT04933266Recruiting
Nerve block plan for breast surgery
This trial studies a type of pain-control injection (a nerve block) to help with anesthesia during breast cancer surgery. It may help improve comfort and reduce pain around the operation.
Sheung Shui, New TerritoriesAges 18–80 - NCT06513065RecruitingPhase 3
Lower dose vs standard dose HIPEC for pseudomyxoma peritonei
This trial compares a lower dose of heated chemotherapy (HIPEC) given during surgery to a standard dose for patients with pseudomyxoma peritonei (a condition where jelly-like mucus builds up in the abdomen). The goal is to see if the lower dose works just as well with fewer side effects.
Basingstoke, HampshireAges 16 years+ - NCT07400003RecruitingPhase 1/Phase 2
Shingles mRNA vaccine safety and immune response study
This trial tests a new mRNA vaccine to prevent shingles (herpes zoster). It checks if the vaccine is safe and helps your body build immunity. It's for adults aged 40 or older (phase 1) or 50+ (phase 2).
XinjiangAges 40 years+ - NCT07514741Enrolling by invitation
Testing a Prebiotic Blend in Healthy Adults
This study tests whether a prebiotic blend (a type of fiber supplement that feeds beneficial gut bacteria) is safe and works well in healthy people. You'll take the supplement daily for a set period while wearing a fitness tracker to see if it affects your health and activity.
West Hollywood, CaliforniaAges 18–60 - NCT07125573Enrolling by invitation
Esketamine and dexmedetomidine for recovery after lung surgery
This trial tests if adding two medicines (esketamine and dexmedetomidine) during your thoracoscopic (keyhole) lung surgery helps you recover better and feel less discomfort afterward.
Kunming, YunnanAges 18–65 - NCT07087327RecruitingPhase 3
Long-term study of EB-1020 for children with ADHD
This trial tests a new medication, EB-1020, over a longer period in children with ADHD. It aims to see if the drug continues to be safe and effective beyond the initial 6-week treatment. Some participants may have already been in a previous EB-1020 study, while others are new.
SapporoAges 6–17
Common questions
- Are there clinical trials studying Low Dose?
- Yes. Clin2 currently lists 459 recruiting studies that include Low Dose, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Low Dose trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Low Dose an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Low Dose or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.