Treatment
Nicotinamide clinical trials
We’re tracking 51 recruiting studies that include Nicotinamide, each written for real people, not researchers, below.
Recruiting studies
- NCT04844528RecruitingPhase 2
Nicotinamide for CLL patients with recent skin cancer history
This Phase 2 trial tests whether nicotinamide (a form of vitamin B3) can help people with chronic lymphocytic leukemia (CLL) who have had non-melanoma skin cancers in the past 5 years. The study looks at how well new skin cancers can be prevented or reduced.
Salt Lake City, UtahAges 18 years+ - NCT05702398RecruitingEarly Phase 1
Vitamin A and niacinamide for high-risk skin cancer
This early trial tests whether adding vitamin A and niacinamide (a form of vitamin B3) can help people with a history of certain skin cancers reduce new disease. It is designed for adults with specific prior skin cancer or skin lesion treatment patterns.
Providence, Rhode IslandAges 18 years+ - NCT05500170Recruiting
Study of nicotinamide riboside for sleep and thinking
This trial tests whether nicotinamide riboside can improve sleep quality and help with thinking and memory. You may be invited if your sleep is poor and you do not show signs of dementia on a brief mental test.
Buffalo, New YorkAges 65–85 - NCT04614714RecruitingPhase 2/Phase 3
Nicotinamide riboside to boost breast milk for very premature infants
This study tests whether an oral supplement called nicotinamide riboside can increase milk output in mothers of extremely premature babies. If it works, it may help you provide enough breast milk for your baby’s early NICU needs.
Sacramento, CaliforniaAges 18 years+ - NCT04332341RecruitingEarly Phase 1
Nicotinamide riboside during bone marrow transplant
This trial studies whether a supplement called nicotinamide riboside (a vitamin-like product) can be given safely during allogeneic bone marrow transplant. It may help researchers understand how well it works and how it affects recovery for people getting a donor transplant.
Cleveland, OhioAges 18 years+ - NCT04055818RecruitingPhase 1
Testing three medicines for high-risk sickle cell disease
This Phase 1 study tests whether nicotinamide, oral tetrahydrouridine, and decitabine can help people with high-risk sickle cell disease. It is mainly a safety-and-dosing study, but it also looks for signs the medicines may improve disease-related problems.
Chicago, IllinoisAges 18 years+ - NCT05405868RecruitingPhase 3
Nicotinamide for early to moderate open-angle glaucoma
This trial tests whether nicotinamide (a form of vitamin B3) can slow vision changes from open-angle glaucoma. It compares nicotinamide versus a placebo (inactive pill) in adults with early to moderate disease.
Belfast, Northern IrelandAges 18 years+ - NCT07703137Enrolling by invitation
NAD Supplement for Parkinson's Disease Study
This study tests whether a supplement called NAD (a natural substance that helps cells produce energy) can improve symptoms in people with Parkinson's disease. You would take the supplement daily for several weeks, and researchers will check your movement, thinking, and overall well-being.
Oklahoma City, OklahomaAges 55–85 - NCT07649161Recruiting
Nicotinamide Riboside and Brain Energy in Healthy Adults
This study tests whether a vitamin B3-like supplement called nicotinamide riboside can improve how your brain uses energy. Researchers will use brain imaging and blood tests to see if it helps brain function in healthy adults.
Boston, MassachusettsAges 18–65 - NCT07585006RecruitingPhase 1
How nicotine affects the body: comparing e-cigarette liquids
This study compares different nicotine products to understand how they affect your body. Researchers will measure your heart rate, breathing, and blood samples during three short lab visits. The results may help scientists better understand nicotine's effects.
Columbus, OhioAges 21 years+ - NCT07572825RecruitingPhase 1
Safety study of NMN supplement for DHDDS-CDG
This trial tests whether a supplement called NMN is safe and well-tolerated in children and adults with a rare genetic condition called DHDDS-CDG. NMN may help support cellular energy and protein production, which are affected by this condition.
New York, New YorkAges 4 years+ - NCT06162013RecruitingPhase 2
NAD supplement trial for atypical parkinsonism
This trial tests whether a supplement called nicotinamide riboside (NR) can help people with rare forms of parkinsonism (PSP, MSA, or CBS). It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real supplement or a placebo.
Oslo, OsloAges 30–85 - NCT07451496Recruiting
Personalized aging study with lifestyle and supplements
This study tests whether personalized lifestyle advice, supplements, and exercise can help slow aging and improve health. If you are a generally healthy adult aged 50–80 who is not currently exercising, you may be a good fit.
Singapore, SingaporeAges 50–80 - NCT07344636Recruiting
NR supplements and zone 2 training for metabolism
This trial tests whether taking nicotinamide riboside (a vitamin-like supplement) helps your body burn fuel better during moderate exercise, known as zone 2 training. It may benefit healthy adults who want to improve their workout efficiency.
Hong Kong, Please SelectAges 18–80 - NCT07073352Recruiting
Childhood stress and blood vessel aging in young adults
This study looks at how childhood stress might affect blood vessels and aging in young adults. It tests if a certain protein (SIRT1) is linked to early blood vessel aging.
Iowa City, IowaAges 18–30 - NCT07013591RecruitingPhase 2
Nicotinamide mononucleotide for heart surgery recovery
This study tests whether taking nicotinamide mononucleotide (a dietary supplement) before and after heart surgery can help reduce complications and improve recovery. It is for people having heart bypass or valve surgery who are at higher risk of problems after surgery.
Boston, MassachusettsAges 18 years+ - NCT06907329Recruiting
NMN supplement trial for middle-aged adults with metabolic issues
This trial tests whether a sustained-release nicotinamide mononucleotide (NMN) supplement can improve immune aging and metabolism in people aged 50-70 who are overweight or have fatty liver, pre-diabetes, or mild type 2 diabetes.
ShanghaiAges 50–70 - NCT06776510RecruitingPhase 1/Phase 2
NAD for immune thrombocytopenia study
This trial tests if a substance called NAD can help adults with immune thrombocytopenia (ITP) whose platelet levels stay low even after standard treatments. ITP is a condition where the immune system attacks platelets, causing easy bruising and bleeding. The study aims to see if NAD can safely raise platelet counts.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT06627868Recruiting
NAD+ metabolism in human brown fat
This study explores how the body's natural substance NAD+ works in brown fat, a type of fat that burns calories. It may help researchers understand metabolism and find new ways to treat obesity.
TurkuAges 30–65 - NCT06592859Recruiting
NMN supplement study for healthy middle-aged and older adults
This study tests if nicotinamide mononucleotide (NMN), a natural supplement, can help middle-aged and older adults stay healthy. It aims to see if NMN can slow aging-related changes in healthy people between 40-70 years old.
Quzhou, ZhejiangAges 39–70 - NCT06488625RecruitingPhase 2/Phase 3
Nicotinamide for mild to moderate ulcerative colitis
This trial tests whether a special oral form of nicotinamide (a type of vitamin B3) can help control mild to moderate ulcerative colitis. The pill is designed to release the medication in the lower part of your gut, where UC often affects. Participation involves taking the study drug and having regular checkups to see how your symptoms and inflammation respond.
Kiel, Schleswig-HolsteinAges 18–80 - NCT06345443Enrolling by invitation
Nicotinamide riboside for blood vessel health
This trial tests a nutritional supplement (nicotinamide riboside) to see how it affects blood flow in healthy adults. It may help understand how to support vascular health as we age.
Rochester, MinnesotaAges 35–70 - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT05194397RecruitingPhase 2
Exercise plus NR supplement to boost fitness after stem-cell transplant
This trial tests whether a supervised exercise program, plus an NR supplement, can improve fitness in young people who have had an allogeneic (donor) stem-cell transplant for certain blood cancers or bone marrow conditions. It’s meant to help with energy and physical ability while monitoring safety.
Duarte, CaliforniaAges 10–30
Common questions
- Are there clinical trials studying Nicotinamide?
- Yes. Clin2 currently lists 51 recruiting studies that include Nicotinamide, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Nicotinamide trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Nicotinamide an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Nicotinamide or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.