Treatment
Nicotine clinical trials
We’re tracking 139 recruiting studies that include Nicotine, each written for real people, not researchers, below.
Recruiting studies
- NCT06654414Recruiting
Smoking cessation support for transgender and gender-diverse adults
This study tests a skills-based program to help transgender and gender-diverse adults quit smoking or vaping. The program focuses on managing stress related to identity and health, and may be more supportive than standard quit programs.
Boston, MassachusettsAges 18 years+ - NCT07712887Recruiting
Studying how IQOS users puff across device models
This study looks at how people who regularly use IQOS inhale from different versions of the device. It aims to understand how the feeling and pattern of use change between models.
Beirut, BeirutAges 18–65 - NCT07568483Recruiting
Web-based smoking cessation support program
This study tests TUBSIS 2.0, a digital program designed to help you quit or cut back on smoking. You'll use it on your computer, tablet, or phone, and researchers will track how it affects your smoking habits over time.
ZurichAges 18 years+ - NCT05660798Recruiting
Switching from cigarettes to heat-not-burn to protect heart arteries
This study looks at whether switching from regular cigarettes to a tobacco heating product slows buildup of plaque in the heart arteries. You’d be guided through smoking change and monitored using heart scans, to see if artery plaque stays the same or improves.
WarsawAges 18–75 - NCT07540780Recruiting
Social media support groups to help teens quit vaping
This study tests whether online support groups on social media can help teenagers stop vaping. You'd join a group with other teens your age working toward the same goal, with support from trained peer mentors.
San Francisco, CaliforniaAges 13 years+ - NCT07491627Enrolling by invitation
Nicotine's effect on gum disease treatment in smokers and non-smokers
This study looks at how smoking and nicotine affect the success of gum disease treatment. It compares results between smokers and non-smokers who have gum disease.
Liège, LiegeAges 18 years+ - NCT05738408Recruiting
Remote smoking help for hospitalized heart patients
This trial tests a phone-based (remote) smoking quit program for people hospitalized for a recent heart-related event. It may help you quit smoking by offering support when you’re in the hospital and afterward.
Burlington, VermontAges 18 years+ - NCT07419425RecruitingPhase 4
Help for Black adults to quit smoking
This study tests a program to help Black adults who smoke quit. It offers support and medication to help you stop smoking.
Phoenix, ArizonaAges 21 years+ - NCT07346092Recruiting
Health beliefs and social behaviors about nicotine pouches
This study looks at how graduate students at Ohio State University perceive and use oral nicotine pouches. The goal is to create better ways to communicate the addictive risks of these products.
Columbus, OhioAges 21 years+ - NCT07298902Recruiting
Non-invasive brain stimulation to help quit smoking
This study tests a new non-invasive brain stimulation technique to help long-term smokers quit. You'll receive a safe magnetic pulse to brain areas linked to cravings, and researchers track your progress.
Houston, TexasAges 20–60 - NCT06106646Recruiting
Vitamin C and smoking in pregnancy: long-term lung health follow-up
This study is checking on the long-term lung health of children whose mothers took vitamin C or a placebo during pregnancy and either smoked or did not smoke. It's a follow-up to see if vitamin C might have lasting benefits for their breathing.
Indianapolis, IndianaAges 6–16 - NCT07292883RecruitingPhase 2
Accelerated TMS for smoking cessation
This trial tests whether a rapid form of brain stimulation (TMS) can help people stop smoking. It is designed for adults who are ready to quit within the next month.
Penetanguishene, OntarioAges 18 years+ - NCT07210268Recruiting
Brain stimulation for nicotine addiction treatment
This trial tests a new method called temporal interference to stimulate the brain and help people who vape nicotine reduce their addiction. It aims to see if this non-invasive approach can make it easier to quit.
Bloomington, IndianaAges 21–50 - NCT06932718Recruiting
Smoking cessation program for Hong Kong workers
This study tests a workplace program to help people in Hong Kong quit smoking. It includes support through instant messaging and check-ins over 12 months.
Hong KongAges 18 years+ - NCT05257629RecruitingPhase 3
Aggressive smoking quit program after heart problems
This trial tests whether a strong quit plan using varenicline (a quit pill) plus nicotine e-cigarettes, along with counseling, helps people stop smoking after a recent heart-related event. It’s aimed at people who want to quit and can safely stay involved for about a year.
New Westminster, British ColumbiaAges 18 years+ - NCT07167225Recruiting
Chemical exposure in young adults who use e-cigarettes and cannabis
This study looks at how young adults who use e-cigarettes, cannabis, or both are exposed to harmful chemicals. It aims to understand the health effects of using these products together.
Buffalo, New YorkAges 18–25 - NCT07148232RecruitingPhase 4
Helping people experiencing homelessness quit smoking
This study tests an extended program to help people who are homeless and smoke at least 5 cigarettes a day quit smoking. It provides nicotine replacement therapy (like patches or gum) and support over time.
San Francisco, CaliforniaAges 18 years+ - NCT07132814Recruiting
Testing abuse potential of five oral nicotine products
This study tests how much people might want to use five different types of modern oral nicotine products (like pouches or lozenges) compared to smoking their usual cigarette. It helps researchers understand if these products could be less addictive than cigarettes.
Overland Park, KansasAges 21–60 - NCT07129265Enrolling by invitation
Understanding vape marketing study for youth
This study looks at how young people understand vape marketing. You might join a working group or a focus group to share your thoughts.
Boston, MassachusettsAges 13 years+ - NCT07089901RecruitingPhase 4
Smartphone app to help you quit smoking
This study uses a smartphone app and a breath carbon monoxide monitor to help people understand their smoking patterns and quit. It tests a digital approach to quitting, and you'll get support with nicotine replacement therapy if eligible.
Durham, North CarolinaAges 21 years+ - NCT07040566RecruitingPhase 2
Varenicline to help stop vaping
This trial tests whether varenicline, a medicine that reduces cravings, can help people quit using e-cigarettes that contain nicotine. You must be a daily nicotine vaper and live in Connecticut or South Carolina.
New Haven, ConnecticutAges 18 years+ - NCT07014124Recruiting
Helping smoking fathers quit for their sick child
This study tests whether helping smoking fathers quit can improve their child's health. You and your child will get support through a messaging app, and the child will provide saliva samples.
Hong Kong, PokfulamAges 18 years+ - NCT06991712RecruitingPhase 2
NAD supplements for nerve health in glaucoma
This trial tests whether NAD precursor supplements can improve nerve health and vision in people with glaucoma. If you have glaucoma with mild to moderate vision loss, this study may help understand if these supplements could protect your optic nerve.
Wong Chuk HangAges 18 years+ - NCT06924697Enrolling by invitation
Testing a diabetes drug to help men quit smoking
This study tests if a medication used for type 2 diabetes (GLP-1 receptor agonists) can also reduce smoking in men with diabetes who smoke. If you qualify, you may receive this drug or a standard diabetes pill to see if it helps you smoke less.
Shanghai, Shanghai MunicipalityAges 18–75
Common questions
- Are there clinical trials studying Nicotine?
- Yes. Clin2 currently lists 139 recruiting studies that include Nicotine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Nicotine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Nicotine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Nicotine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.