Treatment
Nicotine Oral Pouch clinical trials
We’re tracking 13 recruiting studies that include Nicotine Oral Pouch, each written for real people, not researchers, below.
Recruiting studies
- NCT07503925RecruitingPhase 4
THRIVE Study: Oral nicotine pouches and health
This study looks at how oral nicotine pouches (a type of smokeless tobacco product) affect health. If you use these pouches daily and meet a few other conditions, you may help researchers understand their public health impact.
Columbus, OhioAges 21 years+ - NCT06072547Recruiting
Can flavored nicotine pouches help you smoke less?
This study tests if flavored nicotine pouches can help adults who smoke at least 5 cigarettes a day switch away from smoking. You'll use the pouches instead of cigarettes, and researchers will track your smoking habits.
Raleigh, North CarolinaAges 22–65 - NCT06315881RecruitingPhase 2
Study of Nicotine Pouches for Cigarette or Snuff Users
This trial tests nicotine pouches (like small pouches you put in your mouth) as a way to help people who smoke cigarettes or use moist snuff. It studies how your body reacts to these pouches under controlled conditions and during daily life.
Columbus, OhioAges 21 years+ - NCT06763536Recruiting
Comparing nicotine pouches vs. nicotine patches or gum to help smokers in rural Appalachia quit
This study tests if oral nicotine pouches work better than nicotine patches or gum to help you smoke less. You’ll use one of these products for a while and check in with the study team. This is for adults who live in rural Appalachian counties and smoke at least 5 cigarettes a day.
Columbus, OhioAges 21 years+ - NCT07625956Enrolling by invitationPhase 4
Nicotine Pouches as a Smoking Substitute Study
This study tests whether nicotine pouches (small pouches you place in your mouth) can help smokers quit or reduce combustible cigarettes. You'll use the pouches as a substitute and attend visits in Charleston, SC to see if this approach works better with new support strategies.
Charleston, South CarolinaAges 21 years+ - NCT06529055Enrolling by invitation
Caffeine and nicotine pouch effects on exercise and brain function
This trial tests how caffeine and nicotine pouches affect your body during exercise, including heart function, thinking, and behavior. It looks at short bursts of high-intensity activity in healthy men who already exercise regularly.
Hattiesburg, MississippiAges 21–40 - NCT07698470Recruiting
Brain response to smoking cues after using nicotine pouches
This study looks at how your brain reacts to smoking cues after using an oral nicotine pouch. You would need to try the pouch and avoid nicotine for 12 hours before each session.
Los Angeles, CaliforniaAges 21–55 - NCT06043362Recruiting
Nicotine pouches for daily smokers
This study tests if nicotine pouches can help daily smokers reduce how many cigarettes they smoke. You'll try nicotine pouches, and researchers will track your progress.
Hershey, PennsylvaniaAges 21–70 - NCT07111234Recruiting
Studying flavored nicotine pouches to understand user preferences
This study tests different flavors and cooling agents in oral nicotine pouches to see which ones people prefer. It may help develop safer alternatives for people who currently smoke cigarettes.
Columbus, OhioAges 21 years+ - NCT07128329RecruitingPhase 1
Acute effects of oral nicotine pouches
This study tests how oral nicotine pouches affect the body, including heart rate and blood pressure, in both daily smokers and people who have used very little nicotine. It helps researchers understand the immediate effects of these pouches.
Baltimore, MarylandAges 21 years+ - NCT07095140Recruiting
Nicotine and flavor effects on alcohol use study
This study tests how different nicotine levels and flavors in oral nicotine products affect alcohol drinking in young adults who use nicotine daily. It could help understand how to reduce alcohol-related harm.
Columbus, OhioAges 21–30 - NCT06372899Recruiting
Switching to E-cigarettes or Nicotine Pouches for Smokers
This study tests whether switching to e-cigarettes or nicotine pouches can help smokers who have tried many times to quit. If you are a heavy smoker (at least 5 cigarettes a day) and have failed to quit before, this trial may offer a new way to reduce harm from smoking.
Philadelphia, PennsylvaniaAges 21 years+ - NCT07346092Recruiting
Health beliefs and social behaviors about nicotine pouches
This study looks at how graduate students at Ohio State University perceive and use oral nicotine pouches. The goal is to create better ways to communicate the addictive risks of these products.
Columbus, OhioAges 21 years+
What Nicotine Oral Pouch is being studied for
Conditions with recruiting Nicotine Oral Pouch studies.
Common questions
- Are there clinical trials studying Nicotine Oral Pouch?
- Yes. Clin2 currently lists 13 recruiting studies that include Nicotine Oral Pouch, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Nicotine Oral Pouch trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Nicotine Oral Pouch an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Nicotine Oral Pouch or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.