Tranexamic acid to prevent worsening chronic brain bleed
Treatments studied
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This Phase 3 study tests whether tranexamic acid (a medicine that helps blood clot) can stop a chronic subdural hematoma from getting worse. It’s for people diagnosed by CT who are being treated without surgery at first.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a chronic subdural hematoma confirmed on a CT scan
- Your first treatment plan is non-surgical (conservative care) based on symptoms
- You have a Glasgow Coma Scale score of 14 or higher
- Your mNIHSS score is 4 or lower, with no worsening symptoms between doctor visits
- You have no planned primary surgery due to severe headache, major midline shift, or very short life expectancy
- You can safely take medicine by mouth and consent can be obtained
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial is testing whether giving a medicine called tranexamic acid (TXA) during surgery helps prevent rebleeding after draining a chronic subdural hematoma. TXA helps stop bleeding, and the goal is to reduce the chance the hematoma comes back.
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