Tranexamic acid for symptomatic subdural blood clots
Treatments studied
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This trial studies whether tranexamic acid (a medicine that helps slow blood breakdown) can improve outcomes for people with symptomatic subdural hematoma—blood collecting between the brain and its outer covering. You may be able to join if you’re older, have bleeding seen on CT, symptoms linked to the bleed, and meet several safety and timing rules.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 45 or older
- Body weight between 45 and 150 kg
- CT scan shows a subdural hematoma at least 8 mm thick
- You have symptoms that fit with the subdural hematoma (like headache, confusion, weakness/numbness, speech/vision problems, seizures, or drowsiness)
- You can take the study medicine as planned (or have a caregiver who can administer it)
- You have no key “not eligible” safety issues (such as pregnancy, severe kidney disease, certain clotting/bleeding disorders, or recent major blood clots)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a newer way to treat subdural hematoma—a bleeding problem inside the brain. After surgery to drain the blood, you'll receive an additional minimally invasive procedure (middle meningeal artery embolization) using a new device called NeoCast to help prevent the bleeding from coming back.
This trial tests if a medication called tranexamic acid can help treat chronic subdural hematomas (a type of bleeding on the brain) without surgery. It's for patients who have this condition but don't need immediate surgery.
This Phase 3 study tests whether tranexamic acid (a medicine that helps blood clot) can stop a chronic subdural hematoma from getting worse. It’s for people diagnosed by CT who are being treated without surgery at first.
This trial is testing whether giving a medicine called tranexamic acid (TXA) during surgery helps prevent rebleeding after draining a chronic subdural hematoma. TXA helps stop bleeding, and the goal is to reduce the chance the hematoma comes back.
This trial tests whether giving tranexamic acid (a medicine that helps clots stay stable) along with intensive blood pressure lowering can reduce bleeding in the brain and improve recovery. It is for people who arrive at the hospital very quickly after a hemorrhagic stroke.
This trial studies whether tranexamic acid (a medicine that helps blood clot) can improve outcomes after a spontaneous (not caused by injury) brain bleed. It is designed for adults who arrive soon after stroke symptoms start and meet several safety and timing requirements.
Hear when a new Subdural Hematoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.