PET study of brain chemical changes in stroke apathy
Part of Brain & nervous system, Heart & circulation clinical trials.
This Phase 3 trial uses special brain scans (PET) to understand what brain chemical systems are involved in apathy after stroke. Your results may help researchers better understand the cause of apathy and guide future treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Aged 18 to under 75 years
- Had a stroke about 3 months ago, and your overall disability score is 2 or less
- You must be in a social security health coverage program
- You can sign consent, and you’re able to return to the hospital for follow-up visits (at least two)
- You cannot take certain medicines that can interfere with the PET scan (especially specific heart/brain/anti-allergy and “brain chemical” medications)
- You must be able to have MRI and PET scan procedures (no MRI/PET allergy or contraindications)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a non-invasive brain stimulation treatment called rTMS to see if it can help reduce apathy (lack of motivation) after a stroke. You would receive either real rTMS or a sham (fake) treatment over several sessions.
This study looks at “apathy,” or reduced motivation/interest, in people with schizophrenia or depression. It may help researchers understand what drives apathy and how to measure it in a clearer, more complete way.
This trial tests a new approach using deep brain stimulation (a treatment that uses tiny electrical pulses in the brain) to help with severe apathy—a common and hard-to-treat symptom of Parkinson's disease where you lose interest and motivation. If you've tried medications without success, this study might offer another option.
This study tests if combining a type of brain stimulation (repetitive TMS) with a medication (methylphenidate, commonly used for ADHD) can improve apathy in people with dementia. If you have Alzheimer's or mixed dementia and struggle with low motivation, this trial may help you.
This study tests a medicine called methylphenidate (often used for ADHD) to see if it helps reduce apathy—feelings of lack of motivation or interest—in people with Parkinson's disease. If it works, it could improve your quality of life and daily functioning.
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help improve apathy, or loss of motivation, in people with Parkinson's disease. You must have had symptoms for at least 4 years and be on stable Parkinson's medications.
Hear when a new Apathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.