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NCT04532346Possibly a fitRecruiting

Hydroxychloroquine for genetic lung disease in children

Interstitial Lung DiseaseSurfactant Dysfunction

Treatments studied

Part of Lungs & breathing clinical trials.

This early-phase trial studies whether hydroxychloroquine can help children with certain genetic causes of interstitial lung disease (lung scarring/inflammation). It is designed for kids who are currently stable and have not recently taken hydroxychloroquine.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
60 people
Ages
1 month to 18 years
Study type
Interventional

Who can take part

  • Your child is under 18 years old and has a diagnosis of childhood interstitial lung disease (lung scarring/inflammation).
  • The lung disease is confirmed to be from a genetic cause, such as genes like SFTPC, SFTPB, ABCA3, NKX2-1, or others listed in the study.
  • Your child’s condition is clinically stable, with no major changes to lung or other medicines in the past 4 weeks.
  • Your child has not taken hydroxychloroquine (HCQ) in the past 12 weeks.
  • No severe current infection flare-ups, and no known allergy to hydroxychloroquine or the tablet ingredients.
  • Your child’s kidney function is not too low for the study (based on a GFR test), and they are not in another clinical trial.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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