Test of sildenafil after diaphragm hernia surgery in newborns
Treatments studied
Part of Genetic & congenital, Heart & circulation, Lungs & breathing clinical trials.
This trial studies whether sildenafil (a medicine that helps relax blood vessels) can improve outcomes in babies born with a congenital diaphragmatic hernia (CDH) after they’ve had surgery. Babies are selected based on an ultrasound/echo of heart function after repair.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby is in the Primary Children’s Hospital (PCH) NICU
- Your baby has congenital diaphragmatic hernia (CDH) and already had surgical repair
- Your baby had an echocardiogram 48–72 hours after surgery
- That echocardiogram shows left heart measurements with LVEI ≥ 1.4
- A parent/guardian can give consent within 24 hours after the echocardiogram
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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