Studying clot-balance markers after total knee replacement
Part of Blood & lymphatic, Bones, joints & muscles clinical trials.
This study looks at blood “clotting-lean vs clot-dissolving” balance measured in tiny blood particles to predict clot problems after knee replacement. It may help doctors better identify who is at higher risk for blood clots after surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 to 85 years old
- You are getting your first total knee replacement for arthritis
- Your anesthesiology risk score (ASA) is less than 4
- You can safely receive standard blood-thinner injections (low-molecular-weight heparin, or LMWH) for prevention
- You are not currently on full-dose blood thinners or strong anti-platelet medicines
- You can sign consent and follow the study visits and procedures
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares a personalized approach to preventing blood clots after hip or knee replacement surgery with the standard one-size-fits-all method. The goal is to see if tailoring prevention to each patient works better and is safer.
This trial tests an experimental drug called BT-114143 to see if it reduces bleeding during and after total knee replacement surgery. It may be a good option for people with osteoarthritis who are having their first knee replacement.
This trial compares a new blood thinner called REGN7508 to two standard blood thinners (apixaban and enoxaparin) to prevent blood clots after total knee replacement surgery. The goal is to see which is safer and more effective.
This study compares a special tensioning tool to the standard method for balancing a new knee joint during total knee replacement. It aims to see which technique provides better outcomes.
This study looks at tissue and blood samples from people having knee replacement surgery to understand how knee arthritis works and how materials used in surgery interact with the body. It may help doctors develop better treatments for knee arthritis.
This study tests a new injection called SRSD107 to see if it prevents blood clots after knee replacement surgery, compared to a standard blood thinner (enoxaparin). It might be an option if you are having a planned knee replacement and are otherwise healthy.
Hear when a new Knee Prosthesis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.