miRNAs in Critical Limb Ischemia Study
Part of Heart & circulation clinical trials.
This study looks at small molecules called miRNAs in the blood of people with severe leg artery disease (critical limb ischemia) or belly aortic aneurysm. The goal is to find patterns that may help doctors better understand and treat these conditions.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have critical limb ischemia (CLI) and are scheduled for leg bypass surgery or a major amputation, OR you have an abdominal aortic aneurysm (AAA) and are scheduled for a non-surgical repair (EVAR).
- You are not pregnant.
- You do not have a genetic disease or active cancer.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study follows adults with very poor blood flow to the foot or leg (with wounds or severe pain) who are having a revascularization procedure to improve circulation. It may help doctors understand outcomes after treatment and improve care for people with critical limb ischemia.
This trial tests whether injecting stem cells from donated fat tissue can help people with severe blockages in leg arteries who cannot have surgery or angioplasty. The goal is to see if the treatment is safe and if it can improve blood flow and reduce pain or wounds.
This trial tests whether stem cells from umbilical cord arteries can help people with severe leg pain or ulcers due to blocked arteries. It is for those who cannot have surgery or other procedures.
This trial tests an experimental drug for people with critical limb ischemia, a serious condition where not enough blood reaches the legs. It aims to see if the drug can help with pain or healing of leg ulcers without the need for surgery.
This trial uses a Doppler ultrasound to measure blood flow speed in your leg arteries to see if it can better predict a severe form of peripheral artery disease called critical limb ischemia. You may qualify if you have known artery disease in your leg and are already scheduled for a toe blood pressure test.
This study tests a new way to restore blood flow to the leg in people who have wounds or dead tissue on their foot and have run out of other treatment options. It's for those who have already tried angioplasty twice without success or have severely hardened small arteries.
Hear when a new Critical Limb Ischemia trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.