Cell therapy for leg ulcers in critical limb ischemia
Part of Heart & circulation, Skin clinical trials.
This trial tests a cell-based treatment for people with severe leg ulcers caused by blocked arteries. It aims to heal wounds that haven't improved with standard care and where surgery has not worked or is not possible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a foot or leg ulcer that is at least 1 cm square (up to 3 ulcers, total area no bigger than 20 cm square).
- You have tried standard wound care (like special dressings) for at least 3 weeks without improvement.
- You have been diagnosed with peripheral artery disease, and your leg pulses (ankle) are weak or absent.
- You have had a doctor confirm that surgery or angioplasty cannot restore blood flow to your lower leg, or that it has already been tried and failed in the last year.
- You are not pregnant, do not have an active infection in the ulcer, and do not have cancer or certain infectious diseases (like HIV, hepatitis, or HTLV).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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