Cell therapy for leg ulcers in critical limb ischemia
Part of Heart & circulation, Skin clinical trials.
This trial tests a cell-based treatment for leg ulcers that haven't healed with standard care in people with severe peripheral artery disease. The goal is to see if this therapy can help wounds heal and improve blood flow.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a leg or foot ulcer that is at least 1 cm² and no more than 3 ulcers totaling up to 20 cm².
- Your ulcer has not improved after at least 3 weeks of standard wound care.
- You have peripheral artery disease with poor blood flow in the leg, as shown by tests like an ankle-brachial index (ABI) below 0.9 or above 1.3 in certain arteries.
- You have not had successful revascularization (a procedure to restore blood flow) or the procedure did not fully restore blood flow to the foot.
- You are able to attend follow-up visits and continue your current medications for PAD and other conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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