Early vs. late skull replacement after brain surgery
Part of Brain & nervous system, Heart & circulation, Injuries & trauma clinical trials.
This trial compares putting the skull piece back early (around 8 weeks after the initial surgery) versus later (after 8 weeks) in people who had a hemicraniectomy for high brain pressure. The goal is to see which timing leads to better outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a large brain swelling from a traumatic injury, stroke, or brain bleed that required a special surgery to remove part of your skull (called a decompressive hemicraniectomy).
- At least 4 weeks after that surgery, your surgeon checked the removed skull piece and said it is in good enough shape to be put back (Craniectomy Contour Class A or B).
- Your doctors say you are healthy enough to undergo general anesthesia and another surgery.
- You do not have an active infection (like pneumonia or a bladder infection) in the 6 to 8 weeks before the planned skull replacement.
- You have not had an infection in your brain or at the surgical site since the skull removal.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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