Clin2
NCT06655519Possibly a fitNot yet recruiting

RD140 injection for relapsed or refractory multiple myeloma

Relapsed/Refractory Multiple MyelomaPlasma Cell Leukemia

Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.

This trial tests an experimental injection called RD140 for people with multiple myeloma or plasma cell leukemia that has come back or not responded to previous treatments. The goal is to see if it can help control the disease.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
12 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have multiple myeloma or primary plasma cell leukemia.
  • You have tried at least 3 prior treatments, including a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 antibody.
  • Your disease has progressed despite treatment or within 12 months after your last treatment.
  • You have measurable signs of the disease, such as a certain level of M protein in blood or urine, or a high percentage of plasma cells in your bone marrow.
  • You are generally in good health (ECOG score 0 or 1) and your organs are functioning well enough.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06718270Recruiting· Early Phase 1
Study of CT0596 for Relapsed or Refractory Myeloma

This trial tests a new CAR-T cell therapy called CT0596 for people with multiple myeloma or plasma cell leukemia that has come back or stopped responding to treatment. The goal is to see if this therapy can help control the cancer.

Shanghai, Shanghai Municipality
NCT05219721Recruiting· Phase 1
CAR T-cell study for relapsed multiple myeloma with GPRC5D

This Phase 1 trial tests a CAR T-cell treatment made to target a protein called GPRC5D on myeloma cells. It may help patients whose multiple myeloma or plasma cell leukemia has come back or stopped responding to prior treatments.

Wuhan, Hubei
NCT06515262Recruiting
Testing anti-BCMA-GPRC5D CAR-T cells for relapsed multiple myeloma

This trial tests a new type of cell therapy (CAR-T cells) that targets two proteins, BCMA and GPRC5D, on myeloma cells. It aims to see if it is safe and effective for people whose multiple myeloma has come back or stopped responding to at least three previous treatments.

Kunming, Kunming, Yunnan
NCT05759793Recruiting· Phase 1
CAR T trial for relapsed myeloma targeting GPRC5D

This Phase 1 trial tests a CAR T-cell treatment made to find a specific marker called GPRC5D on myeloma (or plasma cell leukemia) cells. It may help people whose disease has returned or hasn’t responded to several prior treatments.

Shanghai
NCT06472479Not yet recruiting
Car-t cell therapy for relapsed or refractory multiple myeloma

This trial tests a new treatment using your own immune cells (called CAR-T cells) to fight multiple myeloma that has returned or not responded to earlier treatments. The treatment is designed to target and kill myeloma cells more effectively.

Hefei, Anhui
NCT06333509Not yet recruiting· Phase 1/Phase 2
CAR-T cell therapy for relapsed or refractory multiple myeloma or plasma cell leukemia

This trial tests a new treatment called CAR-T cell therapy that uses your own immune cells to fight cancer. It is for people with multiple myeloma or plasma cell leukemia that has come back or not responded to other treatments.

Hear when a new Relapsed/Refractory Multiple Myeloma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.