Clin2
NCT06680037Worth exploringRecruiting

Azer-cel therapy for immune-related neurological diseases

B-cell Mediated Autoimmune Disorders

Part of Brain & nervous system, Cancer, Eyes & vision, Immune system & allergy clinical trials.

This trial is testing an experimental cell therapy called azer-cel for people with certain autoimmune diseases that affect the nervous system. The therapy aims to reduce immune attacks on the body by targeting and removing faulty B cells.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
100 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have one of these conditions: MS, NMOSD, myasthenia gravis, or CIDP
  • For MS: you may be eligible if you are 18–60 and have moderate-to-severe disability (EDSS 3–6.5)
  • For MS: you must have had worsening disability in the last year
  • For NMOSD: you must be 18–75 and have the AQP4 antibody-positive type
  • For myasthenia gravis: you must be 18–75, have the AChR or MuSK antibody, and score at least 6 on the MG-ADL daily living scale
  • For CIDP: you must be 18–75 and have a moderate disability score on the INCAT scale

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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