Preventing early lung infections after severe brain injury
Treatments studied
Part of Brain & nervous system, Injuries & trauma, Lungs & breathing, Mental health clinical trials.
This study tests whether giving an antibiotic (ceftriaxone) early after a severe brain injury can prevent lung infections caused by the breathing machine (ventilator). It is for adults in the ICU who recently started on a ventilator due to a brain emergency.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are on a breathing machine (ventilator) because of a sudden brain injury, such as a stroke, bleeding in the brain, or a head injury.
- You are in or expected to be in an intensive care unit (ICU).
- You have had the breathing tube for less than 12 hours.
- You did not take antibiotics in the week before coming to the hospital and are not taking them now (except routine surgery antibiotics).
- You have no known allergy to the antibiotic ceftriaxone, are not pregnant, and are expected to survive beyond 90 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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