Does donor-patient sex matching improve blood transfusion outcomes?
Part of Blood & lymphatic, Heart & circulation clinical trials.
This trial tests whether giving ICU patients blood from a donor of the same sex (male-to-male or female-to-female) leads to better recovery compared to mismatched transfusions. The goal is to see if matching donor and patient sex makes a difference in how well patients do.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You are admitted to an intensive care unit (ICU) in a participating hospital
- You need a red blood cell transfusion
- You are not currently having a massive bleed (needing 4 or more units of blood at once or an emergency hemorrhage protocol)
- You have a valid Ontario Health Insurance Plan (OHIP) card
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether a new set of guidelines can help doctors and nurses give red blood cell transfusions more consistently in pediatric intensive care. It aims to make transfusion decisions safer and more uniform for children in the ICU.
This study looks at whether receiving red blood cell transfusions from O-type donors changes outcomes for people with low-risk myelodysplastic syndrome (MDS). It may help doctors choose which blood types to use to improve how patients feel and function over time.
This study tests whether giving red blood cells matched to your child’s RH (a blood marker) can improve safety and fit for people with sickle cell disease who need regular transfusions. It may help reduce mismatches by using blood units selected to match the child’s blood type more closely.
This trial tests whether giving more or fewer red blood cell transfusions is better for adult patients on ECMO (a machine that helps your heart and lungs work). The goal is to find the best transfusion approach to improve outcomes.
This study tests whether a personalized plan for when to give blood transfusions works better than the usual approach in people having heart surgery with a heart-lung machine. The goal is to find a safer and more effective way to manage transfusions during recovery.
This trial looks at how blood transfusions were used in intensive care units and how that affected illness and survival. It may help improve transfusion decisions for future ICU patients.
Hear when a new Sex Differences trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.