UCAR T-cell therapy for autoimmune diseases
Part of Blood & lymphatic, Bones, joints & muscles, Brain & nervous system, Cancer, Heart & circulation, Immune system & allergy, Skin clinical trials.
This trial tests a new treatment using UCAR T-cells that target CD19 and BCMA proteins, for people with autoimmune diseases like lupus or arthritis that have come back or not responded to other treatments. It aims to see if this therapy can help control the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have an autoimmune disease that has relapsed or is resistant to treatment, such as lupus or rheumatoid arthritis.
- Your blood tests must show certain levels of white blood cells, red blood cells, and platelets.
- Your liver and kidney function must be within acceptable limits.
- You must be willing to use birth control if needed, and not be pregnant or breastfeeding.
- You cannot have serious infections, heart problems, or certain cancers in the past 5 years.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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