Study of adalimumab to delay Parkinson's symptoms in sleep disorder
Treatments studied
Part of Brain & nervous system, Hormones & metabolism, Mental health clinical trials.
This trial tests whether adalimumab, an immune system drug, helps people with REM sleep behavior disorder (a condition that may warn of Parkinson's disease) stay healthy longer. Participants will receive injections of the drug or a placebo to see if it prevents Parkinson's-related brain problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have REM sleep behavior disorder, confirmed by a sleep study.
- You have a reduced sense of smell.
- You do not already have Parkinson's disease or Lewy body dementia.
- You score at least 23 on a cognitive test.
- You have a study partner who can accompany you to visits and support you.
- You are able to inject the study drug yourself or have someone who can help.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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